Atlas of Genetics and Cytogenetics in Oncology and Haematology


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UCK1 (uridine-cytidine kinase 1)

Identity

Alias_symbol (synonym)URK1
FLJ12255
Other alias
HGNC (Hugo) UCK1
LocusID (NCBI) 83549
Atlas_Id 75455
Location 9q34.13  [Link to chromosome band 9q34]
Location_base_pair Starts at 134399183 and ends at 134406662 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BRSK1 (19q13.42) / UCK1 (9q34.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UCK1   14859
Cards
Entrez_Gene (NCBI)UCK1  83549  uridine-cytidine kinase 1
AliasesURK1
GeneCards (Weizmann)UCK1
Ensembl hg19 (Hinxton)ENSG00000130717 [Gene_View]  chr9:134399183-134406662 [Contig_View]  UCK1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000130717 [Gene_View]  chr9:134399183-134406662 [Contig_View]  UCK1 [Vega]
ICGC DataPortalENSG00000130717
TCGA cBioPortalUCK1
AceView (NCBI)UCK1
Genatlas (Paris)UCK1
WikiGenes83549
SOURCE (Princeton)UCK1
Genetics Home Reference (NIH)UCK1
Genomic and cartography
GoldenPath hg19 (UCSC)UCK1  -     chr9:134399183-134406662 -  9q34.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)UCK1  -     9q34.13   [Description]    (hg38-Dec_2013)
EnsemblUCK1 - 9q34.13 [CytoView hg19]  UCK1 - 9q34.13 [CytoView hg38]
Mapping of homologs : NCBIUCK1 [Mapview hg19]  UCK1 [Mapview hg38]
OMIM609328   
Gene and transcription
Genbank (Entrez)AA809511 AF125106 AF237290 AF254133 AK022317
RefSeq transcript (Entrez)NM_001135954 NM_001261450 NM_001261451 NM_031432
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929367
Consensus coding sequences : CCDS (NCBI)UCK1
Cluster EST : UnigeneHs.9597 [ NCBI ]
CGAP (NCI)Hs.9597
Alternative Splicing GalleryENSG00000130717
Gene ExpressionUCK1 [ NCBI-GEO ]   UCK1 [ EBI - ARRAY_EXPRESS ]   UCK1 [ SEEK ]   UCK1 [ MEM ]
Gene Expression Viewer (FireBrowse)UCK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83549
GTEX Portal (Tissue expression)UCK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HA47   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HA47  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HA47
Splice isoforms : SwissVarQ9HA47
Catalytic activity : Enzyme2.7.1.48 [ Enzyme-Expasy ]   2.7.1.482.7.1.48 [ IntEnz-EBI ]   2.7.1.48 [ BRENDA ]   2.7.1.48 [ KEGG ]   
PhosPhoSitePlusQ9HA47
Domains : Interpro (EBI)P-loop_NTPase    PRK/URK    UCK-1    Uridine_kinase_like   
Domain families : Pfam (Sanger)PRK (PF00485)   
Domain families : Pfam (NCBI)pfam00485   
Conserved Domain (NCBI)UCK1
DMDM Disease mutations83549
Blocks (Seattle)UCK1
PDB (SRS)2JEO    2UVQ   
PDB (PDBSum)2JEO    2UVQ   
PDB (IMB)2JEO    2UVQ   
PDB (RSDB)2JEO    2UVQ   
Structural Biology KnowledgeBase2JEO    2UVQ   
SCOP (Structural Classification of Proteins)2JEO    2UVQ   
CATH (Classification of proteins structures)2JEO    2UVQ   
SuperfamilyQ9HA47
Human Protein AtlasENSG00000130717
Peptide AtlasQ9HA47
HPRD18256
IPIIPI00027771   IPI00303595   IPI00983448   IPI00902890   IPI00644228   
Protein Interaction databases
DIP (DOE-UCLA)Q9HA47
IntAct (EBI)Q9HA47
FunCoupENSG00000130717
BioGRIDUCK1
STRING (EMBL)UCK1
ZODIACUCK1
Ontologies - Pathways
QuickGOQ9HA47
Ontology : AmiGOuridine kinase activity  ATP binding  cytosol  pyrimidine nucleobase metabolic process  phosphorylation  nucleoside kinase activity  pyrimidine nucleoside salvage  UMP salvage  CTP salvage  small molecule metabolic process  nucleobase-containing small molecule metabolic process  
Ontology : EGO-EBIuridine kinase activity  ATP binding  cytosol  pyrimidine nucleobase metabolic process  phosphorylation  nucleoside kinase activity  pyrimidine nucleoside salvage  UMP salvage  CTP salvage  small molecule metabolic process  nucleobase-containing small molecule metabolic process  
Pathways : KEGGPyrimidine metabolism    Drug metabolism - other enzymes   
NDEx NetworkUCK1
Atlas of Cancer Signalling NetworkUCK1
Wikipedia pathwaysUCK1
Orthology - Evolution
OrthoDB83549
GeneTree (enSembl)ENSG00000130717
Phylogenetic Trees/Animal Genes : TreeFamUCK1
HOVERGENQ9HA47
HOGENOMQ9HA47
Homologs : HomoloGeneUCK1
Homology/Alignments : Family Browser (UCSC)UCK1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUCK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UCK1
dbVarUCK1
ClinVarUCK1
1000_GenomesUCK1 
Exome Variant ServerUCK1
ExAC (Exome Aggregation Consortium)UCK1 (select the gene name)
Genetic variants : HAPMAP83549
Genomic Variants (DGV)UCK1 [DGVbeta]
DECIPHER (Syndromes)9:134399183-134406662  ENSG00000130717
CONAN: Copy Number AnalysisUCK1 
Mutations
ICGC Data PortalUCK1 
TCGA Data PortalUCK1 
Broad Tumor PortalUCK1
OASIS PortalUCK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUCK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUCK1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UCK1
DgiDB (Drug Gene Interaction Database)UCK1
DoCM (Curated mutations)UCK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UCK1 (select a term)
intoGenUCK1
Cancer3DUCK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609328   
Orphanet
MedgenUCK1
Genetic Testing Registry UCK1
NextProtQ9HA47 [Medical]
TSGene83549
GENETestsUCK1
Huge Navigator UCK1 [HugePedia]
snp3D : Map Gene to Disease83549
BioCentury BCIQUCK1
ClinGenUCK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83549
Chemical/Pharm GKB GenePA134861770
Clinical trialUCK1
Miscellaneous
canSAR (ICR)UCK1 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUCK1
EVEXUCK1
GoPubMedUCK1
iHOPUCK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:50:44 CET 2017

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