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UCKL1 (uridine-cytidine kinase 1 like 1)

Identity

Alias_namesURKL1
uridine kinase-like 1
uridine-cytidine kinase 1-like 1
Alias_symbol (synonym)FLJ20517
Other aliasUCK1L
HGNC (Hugo) UCKL1
LocusID (NCBI) 54963
Atlas_Id 51318
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 63939829 and ends at 63956447 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DLGAP1 (18p11.31) / UCKL1 (20q13.33)UCKL1 (20q13.33) / SAMD10 (20q13.33)UCKL1 20q13.33 / SAMD10 20q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  UCKL1/SAMD10 (20q13)


External links

Nomenclature
HGNC (Hugo)UCKL1   15938
Cards
Entrez_Gene (NCBI)UCKL1  54963  uridine-cytidine kinase 1 like 1
AliasesUCK1L; URKL1
GeneCards (Weizmann)UCKL1
Ensembl hg19 (Hinxton)ENSG00000198276 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198276 [Gene_View]  ENSG00000198276 [Sequence]  chr20:63939829-63956447 [Contig_View]  UCKL1 [Vega]
ICGC DataPortalENSG00000198276
TCGA cBioPortalUCKL1
AceView (NCBI)UCKL1
Genatlas (Paris)UCKL1
WikiGenes54963
SOURCE (Princeton)UCKL1
Genetics Home Reference (NIH)UCKL1
Genomic and cartography
GoldenPath hg38 (UCSC)UCKL1  -     chr20:63939829-63956447 -  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UCKL1  -     20q13.33   [Description]    (hg19-Feb_2009)
EnsemblUCKL1 - 20q13.33 [CytoView hg19]  UCKL1 - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBIUCKL1 [Mapview hg19]  UCKL1 [Mapview hg38]
OMIM610866   
Gene and transcription
Genbank (Entrez)AJ605558 AK000524 AK128082 AK222559 AK223220
RefSeq transcript (Entrez)NM_001193379 NM_001353475 NM_001353476 NM_001353477 NM_001353478 NM_001353479 NM_001353480 NM_001353481 NM_001353482 NM_017859
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UCKL1
Cluster EST : UnigeneHs.695829 [ NCBI ]
CGAP (NCI)Hs.695829
Alternative Splicing GalleryENSG00000198276
Gene ExpressionUCKL1 [ NCBI-GEO ]   UCKL1 [ EBI - ARRAY_EXPRESS ]   UCKL1 [ SEEK ]   UCKL1 [ MEM ]
Gene Expression Viewer (FireBrowse)UCKL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54963
GTEX Portal (Tissue expression)UCKL1
Human Protein AtlasENSG00000198276-UCKL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWZ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWZ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWZ5
Splice isoforms : SwissVarQ9NWZ5
PhosPhoSitePlusQ9NWZ5
Domains : Interpro (EBI)P-loop_NTPase    PRibTrfase_dom    PRK/URK    PRTase-like    UCKL1    Uridine_kinase-like   
Domain families : Pfam (Sanger)PRK (PF00485)   
Domain families : Pfam (NCBI)pfam00485   
Conserved Domain (NCBI)UCKL1
DMDM Disease mutations54963
Blocks (Seattle)UCKL1
SuperfamilyQ9NWZ5
Human Protein Atlas [tissue]ENSG00000198276-UCKL1 [tissue]
Peptide AtlasQ9NWZ5
HPRD15607
IPIIPI00844311   IPI00384294   IPI00847664   IPI00922071   IPI01012723   IPI00645413   IPI00643906   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWZ5
IntAct (EBI)Q9NWZ5
FunCoupENSG00000198276
BioGRIDUCKL1
STRING (EMBL)UCKL1
ZODIACUCKL1
Ontologies - Pathways
QuickGOQ9NWZ5
Ontology : AmiGOuridine kinase activity  uridine kinase activity  protein binding  ATP binding  nucleus  cytosol  viral process  phosphorylation  pyrimidine nucleoside salvage  UMP salvage  CTP salvage  
Ontology : EGO-EBIuridine kinase activity  uridine kinase activity  protein binding  ATP binding  nucleus  cytosol  viral process  phosphorylation  pyrimidine nucleoside salvage  UMP salvage  CTP salvage  
Pathways : KEGGPyrimidine metabolism    Drug metabolism - other enzymes   
NDEx NetworkUCKL1
Atlas of Cancer Signalling NetworkUCKL1
Wikipedia pathwaysUCKL1
Orthology - Evolution
OrthoDB54963
GeneTree (enSembl)ENSG00000198276
Phylogenetic Trees/Animal Genes : TreeFamUCKL1
HOVERGENQ9NWZ5
HOGENOMQ9NWZ5
Homologs : HomoloGeneUCKL1
Homology/Alignments : Family Browser (UCSC)UCKL1
Gene fusions - Rearrangements
Fusion : MitelmanUCKL1/SAMD10 [20q13.33/20q13.33]  
Fusion PortalUCKL1 20q13.33 SAMD10 20q13.33 BRCA
Fusion Cancer (Beijing)DLGAP1 [18p11.31]  -  UCKL1 [20q13.33]  [FUSC002369]
Fusion : QuiverUCKL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUCKL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UCKL1
dbVarUCKL1
ClinVarUCKL1
1000_GenomesUCKL1 
Exome Variant ServerUCKL1
ExAC (Exome Aggregation Consortium)ENSG00000198276
GNOMAD BrowserENSG00000198276
Varsome BrowserUCKL1
Genetic variants : HAPMAP54963
Genomic Variants (DGV)UCKL1 [DGVbeta]
DECIPHERUCKL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUCKL1 
Mutations
ICGC Data PortalUCKL1 
TCGA Data PortalUCKL1 
Broad Tumor PortalUCKL1
OASIS PortalUCKL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUCKL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUCKL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UCKL1
DgiDB (Drug Gene Interaction Database)UCKL1
DoCM (Curated mutations)UCKL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UCKL1 (select a term)
intoGenUCKL1
Cancer3DUCKL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610866   
Orphanet
DisGeNETUCKL1
MedgenUCKL1
Genetic Testing Registry UCKL1
NextProtQ9NWZ5 [Medical]
TSGene54963
GENETestsUCKL1
Target ValidationUCKL1
Huge Navigator UCKL1 [HugePedia]
snp3D : Map Gene to Disease54963
BioCentury BCIQUCKL1
ClinGenUCKL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54963
Chemical/Pharm GKB GenePA38058
Clinical trialUCKL1
Miscellaneous
canSAR (ICR)UCKL1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUCKL1
EVEXUCKL1
GoPubMedUCKL1
iHOPUCKL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:48:23 CET 2018

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