Atlas of Genetics and Cytogenetics in Oncology and Haematology


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UCN2 (urocortin 2)

Identity

Alias_symbol (synonym)UCNI
SRP
URP
UCN-II
Other aliasUR
HGNC (Hugo) UCN2
LocusID (NCBI) 90226
Atlas_Id 55968
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 48561718 and ends at 48563768 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COL7A1 (3p21.31) / UCN2 (3p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UCN2   18414
Cards
Entrez_Gene (NCBI)UCN2  90226  urocortin 2
AliasesSRP; UCN-II; UCNI; UR; 
URP
GeneCards (Weizmann)UCN2
Ensembl hg19 (Hinxton)ENSG00000145040 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145040 [Gene_View]  chr3:48561718-48563768 [Contig_View]  UCN2 [Vega]
ICGC DataPortalENSG00000145040
TCGA cBioPortalUCN2
AceView (NCBI)UCN2
Genatlas (Paris)UCN2
WikiGenes90226
SOURCE (Princeton)UCN2
Genetics Home Reference (NIH)UCN2
Genomic and cartography
GoldenPath hg38 (UCSC)UCN2  -     chr3:48561718-48563768 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UCN2  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblUCN2 - 3p21.31 [CytoView hg19]  UCN2 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBIUCN2 [Mapview hg19]  UCN2 [Mapview hg38]
OMIM605902   
Gene and transcription
Genbank (Entrez)AF320560 BC002647 BC022096 DQ891090 DQ894272
RefSeq transcript (Entrez)NM_033199
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UCN2
Cluster EST : UnigeneHs.631914 [ NCBI ]
CGAP (NCI)Hs.631914
Alternative Splicing GalleryENSG00000145040
Gene ExpressionUCN2 [ NCBI-GEO ]   UCN2 [ EBI - ARRAY_EXPRESS ]   UCN2 [ SEEK ]   UCN2 [ MEM ]
Gene Expression Viewer (FireBrowse)UCN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90226
GTEX Portal (Tissue expression)UCN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96RP3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96RP3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96RP3
Splice isoforms : SwissVarQ96RP3
PhosPhoSitePlusQ96RP3
Domains : Interpro (EBI)CRF    Urocortin_II    Urocortin_II/III   
Domain families : Pfam (Sanger)CRF (PF00473)   
Domain families : Pfam (NCBI)pfam00473   
Domain structure : Prodom (Prabi Lyon)PD455741 (PD455741)   
Conserved Domain (NCBI)UCN2
DMDM Disease mutations90226
Blocks (Seattle)UCN2
PDB (SRS)2RMG    3N95   
PDB (PDBSum)2RMG    3N95   
PDB (IMB)2RMG    3N95   
PDB (RSDB)2RMG    3N95   
Structural Biology KnowledgeBase2RMG    3N95   
SCOP (Structural Classification of Proteins)2RMG    3N95   
CATH (Classification of proteins structures)2RMG    3N95   
SuperfamilyQ96RP3
Human Protein AtlasENSG00000145040
Peptide AtlasQ96RP3
HPRD16171
IPIIPI00030945   
Protein Interaction databases
DIP (DOE-UCLA)Q96RP3
IntAct (EBI)Q96RP3
FunCoupENSG00000145040
BioGRIDUCN2
STRING (EMBL)UCN2
ZODIACUCN2
Ontologies - Pathways
QuickGOQ96RP3
Ontology : AmiGOG-protein coupled receptor binding  receptor binding  hormone activity  extracellular region  extracellular region  extracellular space  cAMP biosynthetic process  response to stress  adenylate cyclase-activating G-protein coupled receptor signaling pathway  digestion  cellular response to nutrient levels  hormone binding  corticotropin-releasing hormone receptor 2 binding  
Ontology : EGO-EBIG-protein coupled receptor binding  receptor binding  hormone activity  extracellular region  extracellular region  extracellular space  cAMP biosynthetic process  response to stress  adenylate cyclase-activating G-protein coupled receptor signaling pathway  digestion  cellular response to nutrient levels  hormone binding  corticotropin-releasing hormone receptor 2 binding  
NDEx NetworkUCN2
Atlas of Cancer Signalling NetworkUCN2
Wikipedia pathwaysUCN2
Orthology - Evolution
OrthoDB90226
GeneTree (enSembl)ENSG00000145040
Phylogenetic Trees/Animal Genes : TreeFamUCN2
HOVERGENQ96RP3
HOGENOMQ96RP3
Homologs : HomoloGeneUCN2
Homology/Alignments : Family Browser (UCSC)UCN2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUCN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UCN2
dbVarUCN2
ClinVarUCN2
1000_GenomesUCN2 
Exome Variant ServerUCN2
ExAC (Exome Aggregation Consortium)UCN2 (select the gene name)
Genetic variants : HAPMAP90226
Genomic Variants (DGV)UCN2 [DGVbeta]
DECIPHERUCN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUCN2 
Mutations
ICGC Data PortalUCN2 
TCGA Data PortalUCN2 
Broad Tumor PortalUCN2
OASIS PortalUCN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUCN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUCN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UCN2
DgiDB (Drug Gene Interaction Database)UCN2
DoCM (Curated mutations)UCN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UCN2 (select a term)
intoGenUCN2
Cancer3DUCN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605902   
Orphanet
MedgenUCN2
Genetic Testing Registry UCN2
NextProtQ96RP3 [Medical]
TSGene90226
GENETestsUCN2
Target ValidationUCN2
Huge Navigator UCN2 [HugePedia]
snp3D : Map Gene to Disease90226
BioCentury BCIQUCN2
ClinGenUCN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90226
Chemical/Pharm GKB GenePA133787055
Clinical trialUCN2
Miscellaneous
canSAR (ICR)UCN2 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUCN2
EVEXUCN2
GoPubMedUCN2
iHOPUCN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:18:17 CEST 2017

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