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UCN3 (urocortin 3)

Identity

Alias (NCBI)SCP
SPC
UCNIII
HGNC (Hugo) UCN3
HGNC Alias symbUCNIII
SPC
HGNC Alias namestresscopin
 prepro-urocortin 3
LocusID (NCBI) 114131
Atlas_Id 50793
Location 10p15.1  [Link to chromosome band 10p15]
Location_base_pair Starts at 5364966 and ends at 5374692 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)UCN3   17781
Cards
Entrez_Gene (NCBI)UCN3    urocortin 3
AliasesSCP; SPC; UCNIII
GeneCards (Weizmann)UCN3
Ensembl hg19 (Hinxton)ENSG00000178473 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178473 [Gene_View]  ENSG00000178473 [Sequence]  chr10:5364966-5374692 [Contig_View]  UCN3 [Vega]
ICGC DataPortalENSG00000178473
TCGA cBioPortalUCN3
AceView (NCBI)UCN3
Genatlas (Paris)UCN3
SOURCE (Princeton)UCN3
Genetics Home Reference (NIH)UCN3
Genomic and cartography
GoldenPath hg38 (UCSC)UCN3  -     chr10:5364966-5374692 +  10p15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UCN3  -     10p15.1   [Description]    (hg19-Feb_2009)
GoldenPathUCN3 - 10p15.1 [CytoView hg19]  UCN3 - 10p15.1 [CytoView hg38]
ImmunoBaseENSG00000178473
Genome Data Viewer NCBIUCN3 [Mapview hg19]  
OMIM605901   
Gene and transcription
Genbank (Entrez)AY026949 BC069530 BC100867 BC100868 BC100869
RefSeq transcript (Entrez)NM_053049
Consensus coding sequences : CCDS (NCBI)UCN3
Gene ExpressionUCN3 [ NCBI-GEO ]   UCN3 [ EBI - ARRAY_EXPRESS ]   UCN3 [ SEEK ]   UCN3 [ MEM ]
Gene Expression Viewer (FireBrowse)UCN3 [ Firebrowse - Broad ]
GenevisibleExpression of UCN3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114131
GTEX Portal (Tissue expression)UCN3
Human Protein AtlasENSG00000178473-UCN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969E3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969E3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969E3
PhosPhoSitePlusQ969E3
Domains : Interpro (EBI)CRF    Urocortin_II/III   
Domain families : Pfam (Sanger)CRF (PF00473)   
Domain families : Pfam (NCBI)pfam00473   
Conserved Domain (NCBI)UCN3
PDB (RSDB)2RMH    3N93   
PDB Europe2RMH    3N93   
PDB (PDBSum)2RMH    3N93   
PDB (IMB)2RMH    3N93   
Structural Biology KnowledgeBase2RMH    3N93   
SCOP (Structural Classification of Proteins)2RMH    3N93   
CATH (Classification of proteins structures)2RMH    3N93   
SuperfamilyQ969E3
AlphaFold pdb e-kbQ969E3   
Human Protein Atlas [tissue]ENSG00000178473-UCN3 [tissue]
HPRD12066
Protein Interaction databases
DIP (DOE-UCLA)Q969E3
IntAct (EBI)Q969E3
BioGRIDUCN3
STRING (EMBL)UCN3
ZODIACUCN3
Ontologies - Pathways
QuickGOQ969E3
Ontology : AmiGOhormone activity  protein binding  extracellular region  extracellular space  adenylate cyclase-activating G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  digestion  response to glucose  hormone-mediated signaling pathway  hormone-mediated signaling pathway  cellular response to nutrient levels  positive regulation of insulin secretion  response to immobilization stress  response to starvation  varicosity  axon terminus  positive regulation of membrane potential  response to corticosterone  corticotropin-releasing hormone receptor binding  corticotropin-releasing hormone receptor binding  corticotropin-releasing hormone receptor 2 binding  cellular response to hypoxia  
Ontology : EGO-EBIhormone activity  protein binding  extracellular region  extracellular space  adenylate cyclase-activating G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  digestion  response to glucose  hormone-mediated signaling pathway  hormone-mediated signaling pathway  cellular response to nutrient levels  positive regulation of insulin secretion  response to immobilization stress  response to starvation  varicosity  axon terminus  positive regulation of membrane potential  response to corticosterone  corticotropin-releasing hormone receptor binding  corticotropin-releasing hormone receptor binding  corticotropin-releasing hormone receptor 2 binding  cellular response to hypoxia  
NDEx NetworkUCN3
Atlas of Cancer Signalling NetworkUCN3
Wikipedia pathwaysUCN3
Orthology - Evolution
OrthoDB114131
GeneTree (enSembl)ENSG00000178473
Phylogenetic Trees/Animal Genes : TreeFamUCN3
Homologs : HomoloGeneUCN3
Homology/Alignments : Family Browser (UCSC)UCN3
Gene fusions - Rearrangements
Fusion : QuiverUCN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUCN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UCN3
dbVarUCN3
ClinVarUCN3
MonarchUCN3
1000_GenomesUCN3 
Exome Variant ServerUCN3
GNOMAD BrowserENSG00000178473
Varsome BrowserUCN3
ACMGUCN3 variants
VarityQ969E3
Genomic Variants (DGV)UCN3 [DGVbeta]
DECIPHERUCN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUCN3 
Mutations
ICGC Data PortalUCN3 
TCGA Data PortalUCN3 
Broad Tumor PortalUCN3
OASIS PortalUCN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUCN3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUCN3
Mutations and Diseases : HGMDUCN3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaUCN3
DgiDB (Drug Gene Interaction Database)UCN3
DoCM (Curated mutations)UCN3
CIViC (Clinical Interpretations of Variants in Cancer)UCN3
Cancer3DUCN3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605901   
Orphanet
DisGeNETUCN3
MedgenUCN3
Genetic Testing Registry UCN3
NextProtQ969E3 [Medical]
GENETestsUCN3
Target ValidationUCN3
Huge Navigator UCN3 [HugePedia]
ClinGenUCN3
Clinical trials, drugs, therapy
MyCancerGenomeUCN3
Protein Interactions : CTDUCN3
Pharm GKB GenePA130413153
Pharm GKB PathwaysPA2026   
PharosQ969E3
Clinical trialUCN3
Miscellaneous
canSAR (ICR)UCN3
HarmonizomeUCN3
DataMed IndexUCN3
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXUCN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:37:18 CEST 2021

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