Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

UCP1 (uncoupling protein 1 (mitochondrial, proton carrier))

Identity

Alias_namesUCP
uncoupling protein 1 (mitochondrial, proton carrier)
Alias_symbol (synonym)SLC25A7
Other alias
HGNC (Hugo) UCP1
LocusID (NCBI) 7350
Atlas_Id 75459
Location 4q31.1  [Link to chromosome band 4q31]
Location_base_pair Starts at 141481050 and ends at 141489959 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UCP1   12517
Cards
Entrez_Gene (NCBI)UCP1  7350  uncoupling protein 1 (mitochondrial, proton carrier)
AliasesSLC25A7; UCP
GeneCards (Weizmann)UCP1
Ensembl hg19 (Hinxton)ENSG00000109424 [Gene_View]  chr4:141481050-141489959 [Contig_View]  UCP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000109424 [Gene_View]  chr4:141481050-141489959 [Contig_View]  UCP1 [Vega]
ICGC DataPortalENSG00000109424
TCGA cBioPortalUCP1
AceView (NCBI)UCP1
Genatlas (Paris)UCP1
WikiGenes7350
SOURCE (Princeton)UCP1
Genetics Home Reference (NIH)UCP1
Genomic and cartography
GoldenPath hg19 (UCSC)UCP1  -     chr4:141481050-141489959 -  4q31.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)UCP1  -     4q31.1   [Description]    (hg38-Dec_2013)
EnsemblUCP1 - 4q31.1 [CytoView hg19]  UCP1 - 4q31.1 [CytoView hg38]
Mapping of homologs : NCBIUCP1 [Mapview hg19]  UCP1 [Mapview hg38]
OMIM113730   601665   
Gene and transcription
Genbank (Entrez)BC069556 BC096736 BC098168 BC098258 BC098352
RefSeq transcript (Entrez)NM_021833
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_012139 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)UCP1
Cluster EST : UnigeneHs.249211 [ NCBI ]
CGAP (NCI)Hs.249211
Alternative Splicing GalleryENSG00000109424
Gene ExpressionUCP1 [ NCBI-GEO ]   UCP1 [ EBI - ARRAY_EXPRESS ]   UCP1 [ SEEK ]   UCP1 [ MEM ]
Gene Expression Viewer (FireBrowse)UCP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7350
GTEX Portal (Tissue expression)UCP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25874   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25874  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25874
Splice isoforms : SwissVarP25874
PhosPhoSitePlusP25874
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mit_uncoupling    Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)UCP1
DMDM Disease mutations7350
Blocks (Seattle)UCP1
SuperfamilyP25874
Human Protein AtlasENSG00000109424
Peptide AtlasP25874
HPRD00221
IPIIPI00299306   
Protein Interaction databases
DIP (DOE-UCLA)P25874
IntAct (EBI)P25874
FunCoupENSG00000109424
BioGRIDUCP1
STRING (EMBL)UCP1
ZODIACUCP1
Ontologies - Pathways
QuickGOP25874
Ontology : AmiGOmitochondrion  mitochondrial inner membrane  regulation of transcription from RNA polymerase II promoter  mitochondrial transport  proton transport  integral component of membrane  oxidative phosphorylation uncoupler activity  respiratory electron transport chain  cellular metabolic process  small molecule metabolic process  brown fat cell differentiation  
Ontology : EGO-EBImitochondrion  mitochondrial inner membrane  regulation of transcription from RNA polymerase II promoter  mitochondrial transport  proton transport  integral component of membrane  oxidative phosphorylation uncoupler activity  respiratory electron transport chain  cellular metabolic process  small molecule metabolic process  brown fat cell differentiation  
Pathways : KEGGPPAR signaling pathway    Huntington's disease   
NDEx NetworkUCP1
Atlas of Cancer Signalling NetworkUCP1
Wikipedia pathwaysUCP1
Orthology - Evolution
OrthoDB7350
GeneTree (enSembl)ENSG00000109424
Phylogenetic Trees/Animal Genes : TreeFamUCP1
HOVERGENP25874
HOGENOMP25874
Homologs : HomoloGeneUCP1
Homology/Alignments : Family Browser (UCSC)UCP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUCP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UCP1
dbVarUCP1
ClinVarUCP1
1000_GenomesUCP1 
Exome Variant ServerUCP1
ExAC (Exome Aggregation Consortium)UCP1 (select the gene name)
Genetic variants : HAPMAP7350
Genomic Variants (DGV)UCP1 [DGVbeta]
DECIPHER (Syndromes)4:141481050-141489959  ENSG00000109424
CONAN: Copy Number AnalysisUCP1 
Mutations
ICGC Data PortalUCP1 
TCGA Data PortalUCP1 
Broad Tumor PortalUCP1
OASIS PortalUCP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUCP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUCP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch UCP1
DgiDB (Drug Gene Interaction Database)UCP1
DoCM (Curated mutations)UCP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UCP1 (select a term)
intoGenUCP1
Cancer3DUCP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM113730    601665   
Orphanet
MedgenUCP1
Genetic Testing Registry UCP1
NextProtP25874 [Medical]
TSGene7350
GENETestsUCP1
Huge Navigator UCP1 [HugePedia]
snp3D : Map Gene to Disease7350
BioCentury BCIQUCP1
ClinGenUCP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7350
Chemical/Pharm GKB GenePA37164
Clinical trialUCP1
Miscellaneous
canSAR (ICR)UCP1 (select the gene name)
Probes
Litterature
PubMed111 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUCP1
EVEXUCP1
GoPubMedUCP1
iHOPUCP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:50:44 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.