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UGCG (UDP-glucose ceramide glucosyltransferase)

Identity

Alias_symbol (synonym)GCS
Other aliasGLCT1
HGNC (Hugo) UGCG
LocusID (NCBI) 7357
Atlas_Id 42763
Location 9q31.3  [Link to chromosome band 9q31]
Location_base_pair Starts at 111896766 and ends at 111935374 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GNG10 (9q31.3) / UGCG (9q31.3)SUSD1 (9q31.3) / UGCG (9q31.3)UGCG (9q31.3) / PVT1 (8q24.21)
UGCG (9q31.3) / UBXN11 (1p36.11)UGCG (9q31.3) / UGCG (9q31.3)SUSD1 9q31.3 / UGCG 9q31.3
UGCG 9q31.3 / UBXN11 1p36.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UGCG   12524
Capds
Entrez_Gene (NCBI)UGCG  7357  UDP-glucose ceramide glucosyltransferase
AliasesGCS; GLCT1
GeneCards (Weizmann)UGCG
Ensembl hg19 (Hinxton)ENSG00000148154 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148154 [Gene_View]  chr9:111896766-111935374 [Contig_View]  UGCG [Vega]
ICGC DataPortalENSG00000148154
TCGA cBioPortalUGCG
AceView (NCBI)UGCG
Genatlas (Paris)UGCG
WikiGenes7357
SOURCE (Princeton)UGCG
Genetics Home Reference (NIH)UGCG
Genomic and cartography
GoldenPath hg38 (UCSC)UGCG  -     chr9:111896766-111935374 +  9q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UGCG  -     9q31.3   [Description]    (hg19-Feb_2009)
EnsemblUGCG - 9q31.3 [CytoView hg19]  UGCG - 9q31.3 [CytoView hg38]
Mapping of homologs : NCBIUGCG [Mapview hg19]  UGCG [Mapview hg38]
OMIM602874   
Gene and transcription
Genbank (Entrez)AJ420423 AK314847 BC038711 BM052821 D50840
RefSeq transcript (Entrez)NM_003358
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UGCG
Cluster EST : UnigeneHs.593014 [ NCBI ]
CGAP (NCI)Hs.593014
Alternative Splicing GalleryENSG00000148154
Gene ExpressionUGCG [ NCBI-GEO ]   UGCG [ EBI - ARRAY_EXPRESS ]   UGCG [ SEEK ]   UGCG [ MEM ]
Gene Expression Viewer (FireBrowse)UGCG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7357
GTEX Portal (Tissue expression)UGCG
Human Protein AtlasENSG00000148154-UGCG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16739   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16739  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16739
Splice isoforms : SwissVarQ16739
Catalytic activity : Enzyme2.4.1.80 [ Enzyme-Expasy ]   2.4.1.802.4.1.80 [ IntEnz-EBI ]   2.4.1.80 [ BRENDA ]   2.4.1.80 [ KEGG ]   
PhosPhoSitePlusQ16739
Domains : Interpro (EBI)Ceramide_glucosylTrfase    Nucleotide-diphossugar_trans   
Domain families : Pfam (Sanger)Glyco_transf_21 (PF13506)   
Domain families : Pfam (NCBI)pfam13506   
Conserved Domain (NCBI)UGCG
DMDM Disease mutations7357
Blocks (Seattle)UGCG
SuperfamilyQ16739
Human Protein Atlas [tissue]ENSG00000148154-UGCG [tissue]
Peptide AtlasQ16739
HPRD04190
IPIIPI00003861   
Protein Interaction databases
DIP (DOE-UCLA)Q16739
IntAct (EBI)Q16739
FunCoupENSG00000148154
BioGRIDUGCG
STRING (EMBL)UGCG
ZODIACUGCG
Ontologies - Pathways
QuickGOQ16739
Ontology : AmiGOGolgi membrane  glucosylceramide biosynthetic process  glycosphingolipid metabolic process  glycosphingolipid biosynthetic process  ceramide glucosyltransferase activity  ceramide glucosyltransferase activity  epidermis development  membrane  integral component of membrane  positive regulation of protein targeting to mitochondrion  
Ontology : EGO-EBIGolgi membrane  glucosylceramide biosynthetic process  glycosphingolipid metabolic process  glycosphingolipid biosynthetic process  ceramide glucosyltransferase activity  ceramide glucosyltransferase activity  epidermis development  membrane  integral component of membrane  positive regulation of protein targeting to mitochondrion  
Pathways : KEGGSphingolipid metabolism   
NDEx NetworkUGCG
Atlas of Cancer Signalling NetworkUGCG
Wikipedia pathwaysUGCG
Orthology - Evolution
OrthoDB7357
GeneTree (enSembl)ENSG00000148154
Phylogenetic Trees/Animal Genes : TreeFamUGCG
HOVERGENQ16739
HOGENOMQ16739
Homologs : HomoloGeneUGCG
Homology/Alignments : Family Browser (UCSC)UGCG
Gene fusions - Rearrangements
Fusion : MitelmanGNG10/UGCG [9q31.3/9q31.3]  [t(9;9)(q31;q31)]  
Fusion : MitelmanSUSD1/UGCG [9q31.3/9q31.3]  [t(9;9)(q31;q32)]  
Fusion : MitelmanUGCG/PVT1 [9q31.3/8q24.21]  [t(8;9)(q24;q31)]  
Fusion : MitelmanUGCG/UBXN11 [9q31.3/1p36.11]  [t(1;9)(p36;q31)]  
Fusion: TCGA_MDACCSUSD1 9q31.3 UGCG 9q31.3 BRCA
Fusion: TCGA_MDACCUGCG 9q31.3 UBXN11 1p36.11 BRCA
Tumor Fusion PortalUGCG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUGCG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UGCG
dbVarUGCG
ClinVarUGCG
1000_GenomesUGCG 
Exome Variant ServerUGCG
ExAC (Exome Aggregation Consortium)ENSG00000148154
GNOMAD BrowserENSG00000148154
Genetic variants : HAPMAP7357
Genomic Variants (DGV)UGCG [DGVbeta]
DECIPHERUGCG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUGCG 
Mutations
ICGC Data PortalUGCG 
TCGA Data PortalUGCG 
Broad Tumor PortalUGCG
OASIS PortalUGCG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUGCG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUGCG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UGCG
DgiDB (Drug Gene Interaction Database)UGCG
DoCM (Curated mutations)UGCG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UGCG (select a term)
intoGenUGCG
Cancer3DUGCG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602874   
Orphanet
DisGeNETUGCG
MedgenUGCG
Genetic Testing Registry UGCG
NextProtQ16739 [Medical]
TSGene7357
GENETestsUGCG
Target ValidationUGCG
Huge Navigator UGCG [HugePedia]
snp3D : Map Gene to Disease7357
BioCentury BCIQUGCG
ClinGenUGCG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7357
Chemical/Pharm GKB GenePA37169
Clinical trialUGCG
Miscellaneous
canSAR (ICR)UGCG (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUGCG
EVEXUGCG
GoPubMedUGCG
iHOPUGCG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:40:43 CET 2017

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