Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

UGT1A5 (UDP glucuronosyltransferase family 1 member A5)

Identity

Alias_namesUDP glycosyltransferase 1 family, polypeptide A5
Alias_symbol (synonym)UGT1E
Other aliasUDPGT
UDPGT 1-5
HGNC (Hugo) UGT1A5
LocusID (NCBI) 54579
Atlas_Id 75469
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 233712992 and ends at 233773299 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UGT1A5   12537
Cards
Entrez_Gene (NCBI)UGT1A5  54579  UDP glucuronosyltransferase family 1 member A5
AliasesUDPGT; UDPGT; UGT1E
GeneCards (Weizmann)UGT1A5
Ensembl hg19 (Hinxton)ENSG00000240224 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000240224 [Gene_View]  chr2:233712992-233773299 [Contig_View]  UGT1A5 [Vega]
ICGC DataPortalENSG00000240224
TCGA cBioPortalUGT1A5
AceView (NCBI)UGT1A5
Genatlas (Paris)UGT1A5
WikiGenes54579
SOURCE (Princeton)UGT1A5
Genetics Home Reference (NIH)UGT1A5
Genomic and cartography
GoldenPath hg38 (UCSC)UGT1A5  -     chr2:233712992-233773299 +  2q37.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UGT1A5  -     2q37.1   [Description]    (hg19-Feb_2009)
EnsemblUGT1A5 - 2q37.1 [CytoView hg19]  UGT1A5 - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBIUGT1A5 [Mapview hg19]  UGT1A5 [Mapview hg38]
OMIM606430   
Gene and transcription
Genbank (Entrez)AY435140 BC141470 DQ383514
RefSeq transcript (Entrez)NM_019078
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UGT1A5
Cluster EST : UnigeneHs.554822 [ NCBI ]
CGAP (NCI)Hs.554822
Alternative Splicing GalleryENSG00000240224
Gene ExpressionUGT1A5 [ NCBI-GEO ]   UGT1A5 [ EBI - ARRAY_EXPRESS ]   UGT1A5 [ SEEK ]   UGT1A5 [ MEM ]
Gene Expression Viewer (FireBrowse)UGT1A5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54579
GTEX Portal (Tissue expression)UGT1A5
Human Protein AtlasENSG00000240224-UGT1A5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35504   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP35504  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP35504
Splice isoforms : SwissVarP35504
Catalytic activity : Enzyme2.4.1.17 [ Enzyme-Expasy ]   2.4.1.172.4.1.17 [ IntEnz-EBI ]   2.4.1.17 [ BRENDA ]   2.4.1.17 [ KEGG ]   
PhosPhoSitePlusP35504
Domaine pattern : Prosite (Expaxy)UDPGT (PS00375)   
Domains : Interpro (EBI)UDP_glucos_trans   
Domain families : Pfam (Sanger)UDPGT (PF00201)   
Domain families : Pfam (NCBI)pfam00201   
Conserved Domain (NCBI)UGT1A5
DMDM Disease mutations54579
Blocks (Seattle)UGT1A5
SuperfamilyP35504
Human Protein Atlas [tissue]ENSG00000240224-UGT1A5 [tissue]
Peptide AtlasP35504
HPRD07335
IPIIPI00472824   IPI00956634   
Protein Interaction databases
DIP (DOE-UCLA)P35504
IntAct (EBI)P35504
FunCoupENSG00000240224
BioGRIDUGT1A5
STRING (EMBL)UGT1A5
ZODIACUGT1A5
Ontologies - Pathways
QuickGOP35504
Ontology : AmiGOglucuronosyltransferase activity  integral component of membrane  intracellular membrane-bounded organelle  xenobiotic glucuronidation  
Ontology : EGO-EBIglucuronosyltransferase activity  integral component of membrane  intracellular membrane-bounded organelle  xenobiotic glucuronidation  
Pathways : KEGGPentose and glucuronate interconversions    Ascorbate and aldarate metabolism    Steroid hormone biosynthesis    Starch and sucrose metabolism    Retinol metabolism    Porphyrin and chlorophyll metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Drug metabolism - other enzymes    Chemical carcinogenesis   
NDEx NetworkUGT1A5
Atlas of Cancer Signalling NetworkUGT1A5
Wikipedia pathwaysUGT1A5
Orthology - Evolution
OrthoDB54579
GeneTree (enSembl)ENSG00000240224
Phylogenetic Trees/Animal Genes : TreeFamUGT1A5
HOVERGENP35504
HOGENOMP35504
Homologs : HomoloGeneUGT1A5
Homology/Alignments : Family Browser (UCSC)UGT1A5
Gene fusions - Rearrangements
Fusion: Tumor Portal UGT1A5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUGT1A5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UGT1A5
dbVarUGT1A5
ClinVarUGT1A5
1000_GenomesUGT1A5 
Exome Variant ServerUGT1A5
ExAC (Exome Aggregation Consortium)ENSG00000240224
GNOMAD BrowserENSG00000240224
Genetic variants : HAPMAP54579
Genomic Variants (DGV)UGT1A5 [DGVbeta]
DECIPHERUGT1A5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUGT1A5 
Mutations
ICGC Data PortalUGT1A5 
TCGA Data PortalUGT1A5 
Broad Tumor PortalUGT1A5
OASIS PortalUGT1A5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUGT1A5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUGT1A5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UGT1A5
DgiDB (Drug Gene Interaction Database)UGT1A5
DoCM (Curated mutations)UGT1A5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UGT1A5 (select a term)
intoGenUGT1A5
Cancer3DUGT1A5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606430   
Orphanet
MedgenUGT1A5
Genetic Testing Registry UGT1A5
NextProtP35504 [Medical]
TSGene54579
GENETestsUGT1A5
Target ValidationUGT1A5
Huge Navigator UGT1A5 [HugePedia]
snp3D : Map Gene to Disease54579
BioCentury BCIQUGT1A5
ClinGenUGT1A5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54579
Chemical/Pharm GKB GenePA37180
Clinical trialUGT1A5
Miscellaneous
canSAR (ICR)UGT1A5 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUGT1A5
EVEXUGT1A5
GoPubMedUGT1A5
iHOPUGT1A5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:34:58 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.