Atlas of Genetics and Cytogenetics in Oncology and Haematology


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UGT2A3 (UDP glucuronosyltransferase family 2 member A3)

Identity

Alias_namesUDP glucuronosyltransferase 2 family, polypeptide A3
Alias_symbol (synonym)FLJ21934
Other alias-
HGNC (Hugo) UGT2A3
LocusID (NCBI) 79799
Atlas_Id 75471
Location 4q13.2  [Link to chromosome band 4q13]
Location_base_pair Starts at 68928459 and ends at 68951791 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLOCK (4q12) / UGT2A3 (4q13.2)PTK2 (8q24.3) / UGT2A3 (4q13.2)PTK2 UGT2A3
CLOCK UGT2A3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UGT2A3   28528
Cards
Entrez_Gene (NCBI)UGT2A3  79799  UDP glucuronosyltransferase family 2 member A3
Aliases
GeneCards (Weizmann)QGT2A1
Ensembl hg19 (Hinxton)ENSG00000135220 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135220 [Gene_View]  chr4:68928459-68951791 [Contig_View]  UGT2A3 [Vega]
ICGC DataPortalENSG00000135220
TCGA cBioPortalUGT2A3
AceView (NCBI)UGT2A3
Genatlas (Paris)UGT2A3
WikiGenes79799
SOURCE (Princeton)UGT2A3
Genetics Home Reference (NIH)UGT2A3
Genomic and cartography
GoldenPath hg38 (UCSC)UGT2A3  -     chr4:68928459-68951791 -  4q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UGT2A3  -     4q13.2   [Description]    (hg19-Feb_2009)
EnsemblUGT2A3 - 4q13.2 [CytoView hg19]  UGT2A3 - 4q13.2 [CytoView hg38]
Mapping of homologs : NCBIUGT2A3 [Mapview hg19]  UGT2A3 [Mapview hg38]
OMIM616382   
Gene and transcription
Genbank (Entrez)AK025587 AK225308 AK293381 AW194955 AY358727
RefSeq transcript (Entrez)NM_024743
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_167250
Consensus coding sequences : CCDS (NCBI)UGT2A3
Cluster EST : UnigeneHs.122583 [ NCBI ]
CGAP (NCI)Hs.122583
Alternative Splicing GalleryENSG00000135220
Gene ExpressionUGT2A3 [ NCBI-GEO ]   UGT2A3 [ EBI - ARRAY_EXPRESS ]   UGT2A3 [ SEEK ]   UGT2A3 [ MEM ]
Gene Expression Viewer (FireBrowse)UGT2A3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79799
GTEX Portal (Tissue expression)UGT2A3
Human Protein AtlasENSG00000135220-UGT2A3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UWM9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UWM9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UWM9
Splice isoforms : SwissVarQ6UWM9
Catalytic activity : Enzyme2.4.1.17 [ Enzyme-Expasy ]   2.4.1.172.4.1.17 [ IntEnz-EBI ]   2.4.1.17 [ BRENDA ]   2.4.1.17 [ KEGG ]   
PhosPhoSitePlusQ6UWM9
Domaine pattern : Prosite (Expaxy)UDPGT (PS00375)   
Domains : Interpro (EBI)UDP_glucos_trans   
Domain families : Pfam (Sanger)UDPGT (PF00201)   
Domain families : Pfam (NCBI)pfam00201   
Conserved Domain (NCBI)UGT2A3
DMDM Disease mutations79799
Blocks (Seattle)UGT2A3
SuperfamilyQ6UWM9
Human Protein Atlas [tissue]ENSG00000135220-UGT2A3 [tissue]
Peptide AtlasQ6UWM9
HPRD08646
IPIIPI00028229   IPI01013536   IPI00967635   
Protein Interaction databases
DIP (DOE-UCLA)Q6UWM9
IntAct (EBI)Q6UWM9
FunCoupENSG00000135220
BioGRIDUGT2A3
STRING (EMBL)UGT2A3
ZODIACUGT2A3
Ontologies - Pathways
QuickGOQ6UWM9
Ontology : AmiGOglucuronosyltransferase activity  integral component of membrane  intracellular membrane-bounded organelle  cellular glucuronidation  
Ontology : EGO-EBIglucuronosyltransferase activity  integral component of membrane  intracellular membrane-bounded organelle  cellular glucuronidation  
Pathways : KEGGPentose and glucuronate interconversions    Ascorbate and aldarate metabolism    Steroid hormone biosynthesis    Starch and sucrose metabolism    Retinol metabolism    Porphyrin and chlorophyll metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Drug metabolism - other enzymes    Chemical carcinogenesis   
NDEx NetworkUGT2A3
Atlas of Cancer Signalling NetworkUGT2A3
Wikipedia pathwaysUGT2A3
Orthology - Evolution
OrthoDB79799
GeneTree (enSembl)ENSG00000135220
Phylogenetic Trees/Animal Genes : TreeFamUGT2A3
HOVERGENQ6UWM9
HOGENOMQ6UWM9
Homologs : HomoloGeneUGT2A3
Homology/Alignments : Family Browser (UCSC)UGT2A3
Gene fusions - Rearrangements
Fusion: TCGAPTK2 UGT2A3
Fusion: TCGACLOCK UGT2A3
Fusion: Tumor Portal UGT2A3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUGT2A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UGT2A3
dbVarUGT2A3
ClinVarUGT2A3
1000_GenomesUGT2A3 
Exome Variant ServerUGT2A3
ExAC (Exome Aggregation Consortium)ENSG00000135220
GNOMAD BrowserENSG00000135220
Genetic variants : HAPMAP79799
Genomic Variants (DGV)UGT2A3 [DGVbeta]
DECIPHERUGT2A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUGT2A3 
Mutations
ICGC Data PortalUGT2A3 
TCGA Data PortalUGT2A3 
Broad Tumor PortalUGT2A3
OASIS PortalUGT2A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUGT2A3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUGT2A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UGT2A3
DgiDB (Drug Gene Interaction Database)UGT2A3
DoCM (Curated mutations)UGT2A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UGT2A3 (select a term)
intoGenUGT2A3
Cancer3DUGT2A3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616382   
Orphanet
MedgenUGT2A3
Genetic Testing Registry UGT2A3
NextProtQ6UWM9 [Medical]
TSGene79799
GENETestsUGT2A3
Target ValidationUGT2A3
Huge Navigator UGT2A3 [HugePedia]
snp3D : Map Gene to Disease79799
BioCentury BCIQUGT2A3
ClinGenUGT2A3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79799
Chemical/Pharm GKB GenePA142670641
Clinical trialUGT2A3
Miscellaneous
canSAR (ICR)UGT2A3 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUGT2A3
EVEXUGT2A3
GoPubMedUGT2A3
iHOPUGT2A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:34:59 CET 2017

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