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UGT2B15 (UDP glucuronosyltransferase family 2 member B15)

Identity

Alias (NCBI)HLUG4
UDPGT 2B8
UDPGT2B15
UDPGTH3
UGT2B8
HGNC (Hugo) UGT2B15
HGNC Alias symbUGT2B8
HGNC Previous nameUDP glycosyltransferase 2 family, polypeptide B15
LocusID (NCBI) 7366
Atlas_Id 46029
Location 4q13.2  [Link to chromosome band 4q13]
Location_base_pair Starts at 68646597 and ends at 68670652 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)UGT2B15   12546
Cards
Entrez_Gene (NCBI)UGT2B15  7366  UDP glucuronosyltransferase family 2 member B15
AliasesHLUG4; UDPGT; UDPGT2B15; UDPGTH3; 
UGT2B8
GeneCards (Weizmann)UGT2B15
Ensembl hg19 (Hinxton)ENSG00000196620 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196620 [Gene_View]  ENSG00000196620 [Sequence]  chr4:68646597-68670652 [Contig_View]  UGT2B15 [Vega]
ICGC DataPortalENSG00000196620
TCGA cBioPortalUGT2B15
AceView (NCBI)UGT2B15
Genatlas (Paris)UGT2B15
WikiGenes7366
SOURCE (Princeton)UGT2B15
Genetics Home Reference (NIH)UGT2B15
Genomic and cartography
GoldenPath hg38 (UCSC)UGT2B15  -     chr4:68646597-68670652 -  4q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UGT2B15  -     4q13.2   [Description]    (hg19-Feb_2009)
GoldenPathUGT2B15 - 4q13.2 [CytoView hg19]  UGT2B15 - 4q13.2 [CytoView hg38]
ImmunoBaseENSG00000196620
genome Data Viewer NCBIUGT2B15 [Mapview hg19]  
OMIM600069   
Gene and transcription
Genbank (Entrez)AF180322 AF548389 AK289419 DA044256 U06641
RefSeq transcript (Entrez)NM_001076
RefSeq genomic (Entrez)NC_000004 NG_052676 NT_167250
Consensus coding sequences : CCDS (NCBI)UGT2B15
Alternative Splicing GalleryENSG00000196620
Gene ExpressionUGT2B15 [ NCBI-GEO ]   UGT2B15 [ EBI - ARRAY_EXPRESS ]   UGT2B15 [ SEEK ]   UGT2B15 [ MEM ]
Gene Expression Viewer (FireBrowse)UGT2B15 [ Firebrowse - Broad ]
GenevisibleExpression of UGT2B15 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7366
GTEX Portal (Tissue expression)UGT2B15
Human Protein AtlasENSG00000196620-UGT2B15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54855   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54855  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54855
Splice isoforms : SwissVarP54855
Catalytic activity : Enzyme2.4.1.17 [ Enzyme-Expasy ]   2.4.1.172.4.1.17 [ IntEnz-EBI ]   2.4.1.17 [ BRENDA ]   2.4.1.17 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP54855
Domaine pattern : Prosite (Expaxy)UDPGT (PS00375)   
Domains : Interpro (EBI)UDP_glucos_trans    UDP_glycos_trans_CS   
Domain families : Pfam (Sanger)UDPGT (PF00201)   
Domain families : Pfam (NCBI)pfam00201   
Conserved Domain (NCBI)UGT2B15
DMDM Disease mutations7366
Blocks (Seattle)UGT2B15
PDB (RSDB)6IPB   
PDB Europe6IPB   
PDB (PDBSum)6IPB   
PDB (IMB)6IPB   
Structural Biology KnowledgeBase6IPB   
SCOP (Structural Classification of Proteins)6IPB   
CATH (Classification of proteins structures)6IPB   
SuperfamilyP54855
Human Protein Atlas [tissue]ENSG00000196620-UGT2B15 [tissue]
Peptide AtlasP54855
HPRD07192
IPIIPI00008905   
Protein Interaction databases
DIP (DOE-UCLA)P54855
IntAct (EBI)P54855
FunCoupENSG00000196620
BioGRIDUGT2B15
STRING (EMBL)UGT2B15
ZODIACUGT2B15
Ontologies - Pathways
QuickGOP54855
Ontology : AmiGOretinoic acid binding  endoplasmic reticulum membrane  xenobiotic metabolic process  UDP-glycosyltransferase activity  steroid metabolic process  glucuronosyltransferase activity  integral component of membrane  intracellular membrane-bounded organelle  cellular glucuronidation  
Ontology : EGO-EBIretinoic acid binding  endoplasmic reticulum membrane  xenobiotic metabolic process  UDP-glycosyltransferase activity  steroid metabolic process  glucuronosyltransferase activity  integral component of membrane  intracellular membrane-bounded organelle  cellular glucuronidation  
Pathways : KEGGPentose and glucuronate interconversions    Ascorbate and aldarate metabolism    Steroid hormone biosynthesis    Starch and sucrose metabolism    Retinol metabolism    Porphyrin and chlorophyll metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Drug metabolism - other enzymes    Chemical carcinogenesis   
NDEx NetworkUGT2B15
Atlas of Cancer Signalling NetworkUGT2B15
Wikipedia pathwaysUGT2B15
Orthology - Evolution
OrthoDB7366
GeneTree (enSembl)ENSG00000196620
Phylogenetic Trees/Animal Genes : TreeFamUGT2B15
HOGENOMP54855
Homologs : HomoloGeneUGT2B15
Homology/Alignments : Family Browser (UCSC)UGT2B15
Gene fusions - Rearrangements
Fusion : QuiverUGT2B15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUGT2B15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UGT2B15
dbVarUGT2B15
ClinVarUGT2B15
MonarchUGT2B15
1000_GenomesUGT2B15 
Exome Variant ServerUGT2B15
GNOMAD BrowserENSG00000196620
Varsome BrowserUGT2B15
Genetic variants : HAPMAP7366
Genomic Variants (DGV)UGT2B15 [DGVbeta]
DECIPHERUGT2B15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUGT2B15 
Mutations
ICGC Data PortalUGT2B15 
TCGA Data PortalUGT2B15 
Broad Tumor PortalUGT2B15
OASIS PortalUGT2B15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUGT2B15  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUGT2B15
Mutations and Diseases : HGMDUGT2B15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UGT2B15
DgiDB (Drug Gene Interaction Database)UGT2B15
DoCM (Curated mutations)UGT2B15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UGT2B15 (select a term)
intoGenUGT2B15
Cancer3DUGT2B15(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600069   
Orphanet
DisGeNETUGT2B15
MedgenUGT2B15
Genetic Testing Registry UGT2B15
NextProtP54855 [Medical]
TSGene7366
GENETestsUGT2B15
Target ValidationUGT2B15
Huge Navigator UGT2B15 [HugePedia]
snp3D : Map Gene to Disease7366
BioCentury BCIQUGT2B15
ClinGenUGT2B15
Clinical trials, drugs, therapy
Protein Interactions : CTD7366
Pharm GKB GenePA37188
Pharm GKB PathwaysPA145011119   PA165111375   PA165964265   PA165986279   PA166117881   PA166123135   
Clinical trialUGT2B15
Miscellaneous
canSAR (ICR)UGT2B15 (select the gene name)
HarmonizomeUGT2B15
DataMed IndexUGT2B15
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUGT2B15
EVEXUGT2B15
GoPubMedUGT2B15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:38:10 CEST 2020

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