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UGT2B4 (UDP glucuronosyltransferase family 2 member B4)

Identity

Alias_namesUDP glycosyltransferase 2 family
Alias_symbol (synonym)UGT2B11
Other aliasHLUG25
UDPGT2B4
UDPGTH1
UDPGTh-1
HGNC (Hugo) UGT2B4
LocusID (NCBI) 7363
Atlas_Id 52838
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 69480165 and ends at 69495908 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF2AK3 (2p11.2) / UGT2B4 (4q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UGT2B4   12553
Cards
Entrez_Gene (NCBI)UGT2B4  7363  UDP glucuronosyltransferase family 2 member B4
AliasesHLUG25; UDPGT2B4; UDPGTH1; UDPGTh-1; 
UGT2B11
GeneCards (Weizmann)UGT2B4
Ensembl hg19 (Hinxton)ENSG00000156096 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156096 [Gene_View]  chr4:69480165-69495908 [Contig_View]  UGT2B4 [Vega]
ICGC DataPortalENSG00000156096
TCGA cBioPortalUGT2B4
AceView (NCBI)UGT2B4
Genatlas (Paris)UGT2B4
WikiGenes7363
SOURCE (Princeton)UGT2B4
Genetics Home Reference (NIH)UGT2B4
Genomic and cartography
GoldenPath hg38 (UCSC)UGT2B4  -     chr4:69480165-69495908 -  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UGT2B4  -     4q13.3   [Description]    (hg19-Feb_2009)
EnsemblUGT2B4 - 4q13.3 [CytoView hg19]  UGT2B4 - 4q13.3 [CytoView hg38]
Mapping of homologs : NCBIUGT2B4 [Mapview hg19]  UGT2B4 [Mapview hg38]
OMIM600067   
Gene and transcription
Genbank (Entrez)AF064200 AF081793 AJ005162 AK292748 AK300084
RefSeq transcript (Entrez)NM_001297615 NM_001297616 NM_021139
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UGT2B4
Cluster EST : UnigeneHs.285887 [ NCBI ]
CGAP (NCI)Hs.285887
Alternative Splicing GalleryENSG00000156096
Gene ExpressionUGT2B4 [ NCBI-GEO ]   UGT2B4 [ EBI - ARRAY_EXPRESS ]   UGT2B4 [ SEEK ]   UGT2B4 [ MEM ]
Gene Expression Viewer (FireBrowse)UGT2B4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7363
GTEX Portal (Tissue expression)UGT2B4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP06133   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP06133  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP06133
Splice isoforms : SwissVarP06133
Catalytic activity : Enzyme2.4.1.17 [ Enzyme-Expasy ]   2.4.1.172.4.1.17 [ IntEnz-EBI ]   2.4.1.17 [ BRENDA ]   2.4.1.17 [ KEGG ]   
PhosPhoSitePlusP06133
Domaine pattern : Prosite (Expaxy)UDPGT (PS00375)   
Domains : Interpro (EBI)UDP_glucos_trans   
Domain families : Pfam (Sanger)UDPGT (PF00201)   
Domain families : Pfam (NCBI)pfam00201   
Conserved Domain (NCBI)UGT2B4
DMDM Disease mutations7363
Blocks (Seattle)UGT2B4
SuperfamilyP06133
Human Protein AtlasENSG00000156096
Peptide AtlasP06133
HPRD02507
IPIIPI00301491   IPI00747579   IPI00963911   IPI00965820   
Protein Interaction databases
DIP (DOE-UCLA)P06133
IntAct (EBI)P06133
FunCoupENSG00000156096
BioGRIDUGT2B4
STRING (EMBL)UGT2B4
ZODIACUGT2B4
Ontologies - Pathways
QuickGOP06133
Ontology : AmiGOretinoic acid binding  endoplasmic reticulum membrane  estrogen catabolic process  xenobiotic metabolic process  metabolic process  glucuronosyltransferase activity  integral component of membrane  organelle membrane  intracellular membrane-bounded organelle  cellular glucuronidation  
Ontology : EGO-EBIretinoic acid binding  endoplasmic reticulum membrane  estrogen catabolic process  xenobiotic metabolic process  metabolic process  glucuronosyltransferase activity  integral component of membrane  organelle membrane  intracellular membrane-bounded organelle  cellular glucuronidation  
Pathways : KEGG   
NDEx NetworkUGT2B4
Atlas of Cancer Signalling NetworkUGT2B4
Wikipedia pathwaysUGT2B4
Orthology - Evolution
OrthoDB7363
GeneTree (enSembl)ENSG00000156096
Phylogenetic Trees/Animal Genes : TreeFamUGT2B4
HOVERGENP06133
HOGENOMP06133
Homologs : HomoloGeneUGT2B4
Homology/Alignments : Family Browser (UCSC)UGT2B4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUGT2B4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UGT2B4
dbVarUGT2B4
ClinVarUGT2B4
1000_GenomesUGT2B4 
Exome Variant ServerUGT2B4
ExAC (Exome Aggregation Consortium)UGT2B4 (select the gene name)
Genetic variants : HAPMAP7363
Genomic Variants (DGV)UGT2B4 [DGVbeta]
DECIPHERUGT2B4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUGT2B4 
Mutations
ICGC Data PortalUGT2B4 
TCGA Data PortalUGT2B4 
Broad Tumor PortalUGT2B4
OASIS PortalUGT2B4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUGT2B4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUGT2B4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UGT2B4
DgiDB (Drug Gene Interaction Database)UGT2B4
DoCM (Curated mutations)UGT2B4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UGT2B4 (select a term)
intoGenUGT2B4
Cancer3DUGT2B4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600067   
Orphanet
MedgenUGT2B4
Genetic Testing Registry UGT2B4
NextProtP06133 [Medical]
TSGene7363
GENETestsUGT2B4
Target ValidationUGT2B4
Huge Navigator UGT2B4 [HugePedia]
snp3D : Map Gene to Disease7363
BioCentury BCIQUGT2B4
ClinGenUGT2B4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7363
Chemical/Pharm GKB GenePA360
Clinical trialUGT2B4
Miscellaneous
canSAR (ICR)UGT2B4 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUGT2B4
EVEXUGT2B4
GoPubMedUGT2B4
iHOPUGT2B4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:01:54 CEST 2017

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