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UGT2B7 (UDP glucuronosyltransferase family 2 member B7)

Identity

Alias_namesUDP glycosyltransferase 2 family
Alias_symbol (synonym)UGT2B9
Other aliasUDPGT 2B7
UDPGT 2B9
UDPGT2B7
UDPGTH2
UDPGTh-2
HGNC (Hugo) UGT2B7
LocusID (NCBI) 7364
Atlas_Id 50279
Location 4q13.2  [Link to chromosome band 4q13]
Location_base_pair Starts at 69096474 and ends at 69112987 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KIT (4q12) / UGT2B7 (4q13.2)UGT2B7 (4q13.2) / FTO (16q12.2)KIT 4q12 / UGT2B7 4q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UGT2B7   12554
Cards
Entrez_Gene (NCBI)UGT2B7  7364  UDP glucuronosyltransferase family 2 member B7
AliasesUDPGT; UDPGT; UDPGT2B7; UDPGTH2; 
UDPGTh-2; UGT2B9
GeneCards (Weizmann)UGT2B7
Ensembl hg19 (Hinxton)ENSG00000171234 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171234 [Gene_View]  chr4:69096474-69112987 [Contig_View]  UGT2B7 [Vega]
ICGC DataPortalENSG00000171234
TCGA cBioPortalUGT2B7
AceView (NCBI)UGT2B7
Genatlas (Paris)UGT2B7
WikiGenes7364
SOURCE (Princeton)UGT2B7
Genetics Home Reference (NIH)UGT2B7
Genomic and cartography
GoldenPath hg38 (UCSC)UGT2B7  -     chr4:69096474-69112987 +  4q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UGT2B7  -     4q13.2   [Description]    (hg19-Feb_2009)
EnsemblUGT2B7 - 4q13.2 [CytoView hg19]  UGT2B7 - 4q13.2 [CytoView hg38]
Mapping of homologs : NCBIUGT2B7 [Mapview hg19]  UGT2B7 [Mapview hg38]
OMIM600068   
Gene and transcription
Genbank (Entrez)AK223142 AK313190 AW614236 BC030974 DQ893657
RefSeq transcript (Entrez)NM_001074 NM_001330719 NM_001349568
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UGT2B7
Cluster EST : UnigeneHs.654424 [ NCBI ]
CGAP (NCI)Hs.654424
Alternative Splicing GalleryENSG00000171234
Gene ExpressionUGT2B7 [ NCBI-GEO ]   UGT2B7 [ EBI - ARRAY_EXPRESS ]   UGT2B7 [ SEEK ]   UGT2B7 [ MEM ]
Gene Expression Viewer (FireBrowse)UGT2B7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7364
GTEX Portal (Tissue expression)UGT2B7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16662   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16662  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16662
Splice isoforms : SwissVarP16662
Catalytic activity : Enzyme2.4.1.17 [ Enzyme-Expasy ]   2.4.1.172.4.1.17 [ IntEnz-EBI ]   2.4.1.17 [ BRENDA ]   2.4.1.17 [ KEGG ]   
PhosPhoSitePlusP16662
Domaine pattern : Prosite (Expaxy)UDPGT (PS00375)   
Domains : Interpro (EBI)UDP_glucos_trans   
Domain families : Pfam (Sanger)UDPGT (PF00201)   
Domain families : Pfam (NCBI)pfam00201   
Conserved Domain (NCBI)UGT2B7
DMDM Disease mutations7364
Blocks (Seattle)UGT2B7
PDB (SRS)2O6L   
PDB (PDBSum)2O6L   
PDB (IMB)2O6L   
PDB (RSDB)2O6L   
Structural Biology KnowledgeBase2O6L   
SCOP (Structural Classification of Proteins)2O6L   
CATH (Classification of proteins structures)2O6L   
SuperfamilyP16662
Human Protein AtlasENSG00000171234
Peptide AtlasP16662
HPRD02508
IPIIPI00029784   IPI00967700   IPI00966879   
Protein Interaction databases
DIP (DOE-UCLA)P16662
IntAct (EBI)P16662
FunCoupENSG00000171234
BioGRIDUGT2B7
STRING (EMBL)UGT2B7
ZODIACUGT2B7
Ontologies - Pathways
QuickGOP16662
Ontology : AmiGOretinoic acid binding  endoplasmic reticulum membrane  lipid metabolic process  androgen metabolic process  glucuronosyltransferase activity  membrane  integral component of membrane  organelle membrane  intracellular membrane-bounded organelle  cellular glucuronidation  extracellular exosome  
Ontology : EGO-EBIretinoic acid binding  endoplasmic reticulum membrane  lipid metabolic process  androgen metabolic process  glucuronosyltransferase activity  membrane  integral component of membrane  organelle membrane  intracellular membrane-bounded organelle  cellular glucuronidation  extracellular exosome  
Pathways : KEGG   
NDEx NetworkUGT2B7
Atlas of Cancer Signalling NetworkUGT2B7
Wikipedia pathwaysUGT2B7
Orthology - Evolution
OrthoDB7364
GeneTree (enSembl)ENSG00000171234
Phylogenetic Trees/Animal Genes : TreeFamUGT2B7
HOVERGENP16662
HOGENOMP16662
Homologs : HomoloGeneUGT2B7
Homology/Alignments : Family Browser (UCSC)UGT2B7
Gene fusions - Rearrangements
Fusion : MitelmanKIT/UGT2B7 [4q12/4q13.2]  [t(4;4)(q12;q13)]  
Fusion: TCGAKIT 4q12 UGT2B7 4q13.2 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUGT2B7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UGT2B7
dbVarUGT2B7
ClinVarUGT2B7
1000_GenomesUGT2B7 
Exome Variant ServerUGT2B7
ExAC (Exome Aggregation Consortium)UGT2B7 (select the gene name)
Genetic variants : HAPMAP7364
Genomic Variants (DGV)UGT2B7 [DGVbeta]
DECIPHERUGT2B7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUGT2B7 
Mutations
ICGC Data PortalUGT2B7 
TCGA Data PortalUGT2B7 
Broad Tumor PortalUGT2B7
OASIS PortalUGT2B7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUGT2B7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUGT2B7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UGT2B7
DgiDB (Drug Gene Interaction Database)UGT2B7
DoCM (Curated mutations)UGT2B7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UGT2B7 (select a term)
intoGenUGT2B7
Cancer3DUGT2B7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600068   
Orphanet
MedgenUGT2B7
Genetic Testing Registry UGT2B7
NextProtP16662 [Medical]
TSGene7364
GENETestsUGT2B7
Huge Navigator UGT2B7 [HugePedia]
snp3D : Map Gene to Disease7364
BioCentury BCIQUGT2B7
ClinGenUGT2B7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7364
Chemical/Pharm GKB GenePA361
Clinical trialUGT2B7
Miscellaneous
canSAR (ICR)UGT2B7 (select the gene name)
Probes
Litterature
PubMed148 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUGT2B7
EVEXUGT2B7
GoPubMedUGT2B7
iHOPUGT2B7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:43:19 CEST 2017

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