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UGT8 (UDP glycosyltransferase 8)

Identity

Alias_namesCGT
UDP-galactose ceramide galactosyltransferase
Other aliasUGT4
HGNC (Hugo) UGT8
LocusID (NCBI) 7368
Atlas_Id 51263
Location 4q26  [Link to chromosome band 4q26]
Location_base_pair Starts at 114598402 and ends at 114678225 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MAPK10 (4q21.3) / UGT8 (4q26)MAPK10 4q21.3 / UGT8 4q26

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UGT8   12555
Cards
Entrez_Gene (NCBI)UGT8  7368  UDP glycosyltransferase 8
AliasesCGT; UGT4
GeneCards (Weizmann)UGT8
Ensembl hg19 (Hinxton)ENSG00000174607 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174607 [Gene_View]  chr4:114598402-114678225 [Contig_View]  UGT8 [Vega]
ICGC DataPortalENSG00000174607
TCGA cBioPortalUGT8
AceView (NCBI)UGT8
Genatlas (Paris)UGT8
WikiGenes7368
SOURCE (Princeton)UGT8
Genetics Home Reference (NIH)UGT8
Genomic and cartography
GoldenPath hg38 (UCSC)UGT8  -     chr4:114598402-114678225 +  4q26   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UGT8  -     4q26   [Description]    (hg19-Feb_2009)
EnsemblUGT8 - 4q26 [CytoView hg19]  UGT8 - 4q26 [CytoView hg38]
Mapping of homologs : NCBIUGT8 [Mapview hg19]  UGT8 [Mapview hg38]
OMIM601291   
Gene and transcription
Genbank (Entrez)AK127970 AK225763 AK294438 AL137342 BC075069
RefSeq transcript (Entrez)NM_001128174 NM_001322112 NM_001322113 NM_001322114 NM_003360
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UGT8
Cluster EST : UnigeneHs.144197 [ NCBI ]
CGAP (NCI)Hs.144197
Alternative Splicing GalleryENSG00000174607
Gene ExpressionUGT8 [ NCBI-GEO ]   UGT8 [ EBI - ARRAY_EXPRESS ]   UGT8 [ SEEK ]   UGT8 [ MEM ]
Gene Expression Viewer (FireBrowse)UGT8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7368
GTEX Portal (Tissue expression)UGT8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16880   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16880  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16880
Splice isoforms : SwissVarQ16880
PhosPhoSitePlusQ16880
Domaine pattern : Prosite (Expaxy)UDPGT (PS00375)   
Domains : Interpro (EBI)UDP_glucos_trans   
Domain families : Pfam (Sanger)UDPGT (PF00201)   
Domain families : Pfam (NCBI)pfam00201   
Conserved Domain (NCBI)UGT8
DMDM Disease mutations7368
Blocks (Seattle)UGT8
SuperfamilyQ16880
Human Protein AtlasENSG00000174607
Peptide AtlasQ16880
HPRD03186
IPIIPI00294455   IPI00965043   
Protein Interaction databases
DIP (DOE-UCLA)Q16880
IntAct (EBI)Q16880
FunCoupENSG00000174607
BioGRIDUGT8
STRING (EMBL)UGT8
ZODIACUGT8
Ontologies - Pathways
QuickGOQ16880
Ontology : AmiGOprotein localization to paranode region of axon  plasma membrane  galactosylceramide biosynthetic process  glycosphingolipid metabolic process  cytoskeleton organization  central nervous system development  peripheral nervous system development  UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity  glucuronosyltransferase activity  integral component of membrane  paranodal junction assembly  intracellular membrane-bounded organelle  N-acylsphingosine galactosyltransferase activity  neuron projection morphogenesis  
Ontology : EGO-EBIprotein localization to paranode region of axon  plasma membrane  galactosylceramide biosynthetic process  glycosphingolipid metabolic process  cytoskeleton organization  central nervous system development  peripheral nervous system development  UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity  glucuronosyltransferase activity  integral component of membrane  paranodal junction assembly  intracellular membrane-bounded organelle  N-acylsphingosine galactosyltransferase activity  neuron projection morphogenesis  
Pathways : KEGGSphingolipid metabolism   
NDEx NetworkUGT8
Atlas of Cancer Signalling NetworkUGT8
Wikipedia pathwaysUGT8
Orthology - Evolution
OrthoDB7368
GeneTree (enSembl)ENSG00000174607
Phylogenetic Trees/Animal Genes : TreeFamUGT8
HOVERGENQ16880
HOGENOMQ16880
Homologs : HomoloGeneUGT8
Homology/Alignments : Family Browser (UCSC)UGT8
Gene fusions - Rearrangements
Fusion : MitelmanMAPK10/UGT8 [4q21.3/4q26]  [t(4;4)(q21;q26)]  
Fusion: TCGAMAPK10 4q21.3 UGT8 4q26 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUGT8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UGT8
dbVarUGT8
ClinVarUGT8
1000_GenomesUGT8 
Exome Variant ServerUGT8
ExAC (Exome Aggregation Consortium)UGT8 (select the gene name)
Genetic variants : HAPMAP7368
Genomic Variants (DGV)UGT8 [DGVbeta]
DECIPHERUGT8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUGT8 
Mutations
ICGC Data PortalUGT8 
TCGA Data PortalUGT8 
Broad Tumor PortalUGT8
OASIS PortalUGT8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUGT8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUGT8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UGT8
DgiDB (Drug Gene Interaction Database)UGT8
DoCM (Curated mutations)UGT8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UGT8 (select a term)
intoGenUGT8
Cancer3DUGT8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601291   
Orphanet
MedgenUGT8
Genetic Testing Registry UGT8
NextProtQ16880 [Medical]
TSGene7368
GENETestsUGT8
Target ValidationUGT8
Huge Navigator UGT8 [HugePedia]
snp3D : Map Gene to Disease7368
BioCentury BCIQUGT8
ClinGenUGT8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7368
Chemical/Pharm GKB GenePA37195
Clinical trialUGT8
Miscellaneous
canSAR (ICR)UGT8 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUGT8
EVEXUGT8
GoPubMedUGT8
iHOPUGT8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:23 CEST 2017

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