UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1)

Identity

Other names	FLJ21925
	ICBP90
	MGC138707
	Np95
	RNF106
	hNP95
HGNC	UHRF1
Location	19p13.3
Location_base_pair	Starts at 4860510 and ends at 4913165 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	UHRF1   12556
Entrez_Gene	UHRF1  29128  ubiquitin-like, containing PHD and RING finger domains, 1
	Cards
GeneCards	UHRF1
Ensembl	ENSG00000034063 [Gene_View]  UHRF1 [Vega]
Genatlas	UHRF1
	Genomic and cartography
GoldenPath	UHRF1  -  19p13.3   chr19:4860510-4913165 +  19p13.3   [Description]    (hg18-March_2006)
Ensembl	UHRF1 - 19p13.3 [CytoView]
NCBI	Mapview
OMIM	607990 Disease map [OMIM]
HomoloGene	UHRF1
	Gene and transcription
Genbank	AA026356 [ ENTREZ ]
Genbank	AB177623 [ ENTREZ ]
Genbank	AB177624 [ ENTREZ ]
Genbank	AF129507 [ ENTREZ ]
Genbank	AF274048 [ ENTREZ ]
RefSeq	NM_001048201 [ SRS ]    NM_001048201 [ ENTREZ ]
RefSeq	NM_013282 [ SRS ]    NM_013282 [ ENTREZ ]
RefSeq	AC_000062 [ SRS ]    AC_000062 [ ENTREZ ]
RefSeq	AC_000151 [ SRS ]    AC_000151 [ ENTREZ ]
RefSeq	NC_000019 [ SRS ]    NC_000019 [ ENTREZ ]
RefSeq	NT_011255 [ SRS ]    NT_011255 [ ENTREZ ]
RefSeq	NW_001838477 [ SRS ]    NW_001838477 [ ENTREZ ]
RefSeq	NW_927173 [ SRS ]    NW_927173 [ ENTREZ ]
CCDS	UHRF1 CCDS - NCBI
AceView	UHRF1 AceView - NCBI
Unigene	Hs.108106 [ SRS ]    Hs.108106 [ NCBI ]
Fast-db	2894 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q2HIX7 [ SRS]    Q2HIX7 [ EXPASY ]     Q2HIX7 [ INTERPRO ]     Q2HIX7 [ UNIPROT ] Q2HIX7 [ VarSplice FASTA ]
Prosite	PS50053 UBIQUITIN_2 [ SRS ]    PS50053 UBIQUITIN_2 [ Expasy ]
Prosite	PS51015 YDG [ SRS ]    PS51015 YDG [ Expasy ]
Prosite	PS01359 ZF_PHD_1 [ SRS ]    PS01359 ZF_PHD_1 [ Expasy ]
Prosite	PS50016 ZF_PHD_2 [ SRS ]    PS50016 ZF_PHD_2 [ Expasy ]
Prosite	PS00518 ZF_RING_1 [ SRS ]    PS00518 ZF_RING_1 [ Expasy ]
Prosite	PS50089 ZF_RING_2 [ SRS ]    PS50089 ZF_RING_2 [ Expasy ]
Interpro	IPR003105 SRA_YDG [ SRS ]    IPR003105 SRA_YDG [ EBI ]
Interpro	IPR000626 Ubiquitin [ SRS ]    IPR000626 Ubiquitin [ EBI ]
Interpro	IPR001965 Znf_PHD [ SRS ]    IPR001965 Znf_PHD [ EBI ]
Interpro	IPR001841 Znf_RING [ SRS ]    IPR001841 Znf_RING [ EBI ]
Interpro	IPR013083 Znf_RING/FYVE/PHD [ SRS ]    IPR013083 Znf_RING/FYVE/PHD [ EBI ]
CluSTr	Q2HIX7
Pfam	PF00628 PHD [ SRS ]    PF00628 PHD [ Sanger ]    pfam00628 [ NCBI-CDD ]
Pfam	PF00240 ubiquitin [ SRS ]    PF00240 ubiquitin [ Sanger ]    pfam00240 [ NCBI-CDD ]
Pfam	PF02182 YDG_SRA [ SRS ]    PF02182 YDG_SRA [ Sanger ]    pfam02182 [ NCBI-CDD ]
Smart	SM00249 PHD [EMBL]
Smart	SM00184 RING [EMBL]
Smart	SM00466 SRA [EMBL]
Smart	SM00213 UBQ [EMBL]
Blocks	Q2HIX7
HPRD	06992
	Protein Interaction databases
DIP	Q2HIX7
IntAct	Q2HIX7
	Polymorphism : SNP, mutations, diseases
OMIM	607990    [ map ]
GENETests	607990
SNP	UHRF1 [dbSNP-NCBI]
SNP	NM_001048201 [SNP-NCI]
SNP	NM_013282 [SNP-NCI]
SNP	UHRF1 [GeneSNPs - Utah]  UHRF1] [HGBASE - SRS]
HAPMAP	UHRF1 [HAPMAP]
HGMD	UHRF1
Genetic Association	UHRF1
CDC HuGE	UHRF1
	General knowledge
Family Browser	UHRF1 [UCSC Family Browser]
SOURCE	NM_001048201
SOURCE	NM_013282
SMD	Hs.108106
SAGE	Hs.108106
GO	transcription factor activity [Amigo]  transcription factor activity
GO	RNA polymerase II transcription factor activity [Amigo]  RNA polymerase II transcription factor activity
GO	protein binding [Amigo]  protein binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	DNA repair [Amigo]  DNA repair
GO	transcription [Amigo]  transcription
GO	regulation of transcription from RNA polymerase II promoter [Amigo]  regulation of transcription from RNA polymerase II promoter
GO	protein modification process [Amigo]  protein modification process
GO	cell cycle [Amigo]  cell cycle
GO	zinc ion binding [Amigo]  zinc ion binding
GO	cell proliferation [Amigo]  cell proliferation
GO	ligase activity [Amigo]  ligase activity
GO	metal ion binding [Amigo]  metal ion binding
KEGG	Tryptophan metabolism
PubGene	UHRF1
TreeFam	UHRF1
CTD	29128 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	UHRF1 Related clones (RZPD - Berlin)
	PubMed
PubMed	24 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:18:27 2008