ULK4 (unc-51 like kinase 4)

2006-10-01  

Identity

HGNC
ULK4
LOCATION
3p22.1
LOCUSID
54986
ALIAS
FAM7C1,REC01035
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54986
MIM: 617010
HGNC: 15784
Ensembl: ENSG00000168038

Variants:

dbSNP: 54986
ClinVar: 54986
TCGA: ENSG00000168038
COSMIC: ULK4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168038ENST00000301831Q96C45
ENSG00000168038ENST00000414606C9JVZ3
ENSG00000168038ENST00000420927A0A0C4DG77
ENSG00000168038ENST00000431379C9JVZ3
ENSG00000168038ENST00000453224C9JVZ3

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
124712432002The protein kinase complement of the human genome.2088
194304792009Genome-wide association study of blood pressure and hypertension.542
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
210457332011Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study.31
204142542010Recapitulation of two genomewide association studies on blood pressure and essential hypertension in the Korean population.29
242840702014Recurrent deletions of ULK4 in schizophrenia: a gene crucial for neuritogenesis and neuronal motility.27
275695462016Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections.14
229457732013Single-nucleotide polymorphism rs1052501 associated with monoclonal gammopathy of undetermined significance and multiple myeloma.6

Citation

Dessen P

ULK4 (unc-51 like kinase 4)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43554/ulk4