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ULK4 (unc-51 like kinase 4)

Identity

Alias_namesunc-51-like kinase 4 (C. elegans)
Alias_symbol (synonym)FLJ20574
REC01035
FAM7C1
Other alias
HGNC (Hugo) ULK4
LocusID (NCBI) 54986
Atlas_Id 43554
Location 3p22.1  [Link to chromosome band 3p22]
Location_base_pair Starts at 41350403 and ends at 41962440 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADAMTS9 (3p14.1) / ULK4 (3p22.1)CCNB1 (5q13.2) / ULK4 (3p22.1)CDKL2 (4q21.1) / ULK4 (3p22.1)
LOC285441 () / ULK4 (3p22.1)RPSA (3p22.1) / ULK4 (3p22.1)SETD2 (3p21.31) / ULK4 (3p22.1)
STX8 (17p13.1) / ULK4 (3p22.1)TRANK1 (3p22.2) / ULK4 (3p22.1)TRIM24 (7q33) / ULK4 (3p22.1)
ULK4 (3p22.1) / ANO10 (3p22.1)ULK4 (3p22.1) / PAQR3 (4q21.21)ADAMTS9 3p14.1 / ULK4 3p22.1
SETD2 3p21.31 / ULK4 3p22.1TRIM24 7q33 / ULK4 3p22.1ULK4 3p22.1 / ANO10 3p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ULK4   15784
Cards
Entrez_Gene (NCBI)ULK4  54986  unc-51 like kinase 4
AliasesFAM7C1; REC01035
GeneCards (Weizmann)ULK4
Ensembl hg19 (Hinxton)ENSG00000168038 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168038 [Gene_View]  chr3:41350403-41962440 [Contig_View]  ULK4 [Vega]
ICGC DataPortalENSG00000168038
TCGA cBioPortalULK4
AceView (NCBI)ULK4
Genatlas (Paris)ULK4
WikiGenes54986
SOURCE (Princeton)ULK4
Genetics Home Reference (NIH)ULK4
Genomic and cartography
GoldenPath hg38 (UCSC)ULK4  -     chr3:41350403-41962440 -  3p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ULK4  -     3p22.1   [Description]    (hg19-Feb_2009)
EnsemblULK4 - 3p22.1 [CytoView hg19]  ULK4 - 3p22.1 [CytoView hg38]
Mapping of homologs : NCBIULK4 [Mapview hg19]  ULK4 [Mapview hg38]
OMIM617010   
Gene and transcription
Genbank (Entrez)AK000581 AK093396 AK304341 AL133104 AW504756
RefSeq transcript (Entrez)NM_001322500 NM_001322501 NM_017886
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ULK4
Cluster EST : UnigeneHs.656192 [ NCBI ]
CGAP (NCI)Hs.656192
Alternative Splicing GalleryENSG00000168038
Gene ExpressionULK4 [ NCBI-GEO ]   ULK4 [ EBI - ARRAY_EXPRESS ]   ULK4 [ SEEK ]   ULK4 [ MEM ]
Gene Expression Viewer (FireBrowse)ULK4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54986
GTEX Portal (Tissue expression)ULK4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96C45   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96C45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96C45
Splice isoforms : SwissVarQ96C45
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ96C45
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Kinase-like_dom    Prot_kinase_dom   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Conserved Domain (NCBI)ULK4
DMDM Disease mutations54986
Blocks (Seattle)ULK4
SuperfamilyQ96C45
Human Protein AtlasENSG00000168038
Peptide AtlasQ96C45
HPRD07928
IPIIPI00807602   IPI00867515   IPI00156532   
Protein Interaction databases
DIP (DOE-UCLA)Q96C45
IntAct (EBI)Q96C45
FunCoupENSG00000168038
BioGRIDULK4
STRING (EMBL)ULK4
ZODIACULK4
Ontologies - Pathways
QuickGOQ96C45
Ontology : AmiGOmicrotubule cytoskeleton organization  protein serine/threonine kinase activity  ATP binding  protein phosphorylation  regulation of neuron projection development  regulation of MAPK cascade  regulation of JNK cascade  regulation of protein kinase C signaling  regulation of p38MAPK cascade  regulation of neuron migration  
Ontology : EGO-EBImicrotubule cytoskeleton organization  protein serine/threonine kinase activity  ATP binding  protein phosphorylation  regulation of neuron projection development  regulation of MAPK cascade  regulation of JNK cascade  regulation of protein kinase C signaling  regulation of p38MAPK cascade  regulation of neuron migration  
NDEx NetworkULK4
Atlas of Cancer Signalling NetworkULK4
Wikipedia pathwaysULK4
Orthology - Evolution
OrthoDB54986
GeneTree (enSembl)ENSG00000168038
Phylogenetic Trees/Animal Genes : TreeFamULK4
HOVERGENQ96C45
HOGENOMQ96C45
Homologs : HomoloGeneULK4
Homology/Alignments : Family Browser (UCSC)ULK4
Gene fusions - Rearrangements
Fusion : MitelmanADAMTS9/ULK4 [3p14.1/3p22.1]  [t(3;3)(p14;p22)]  
Fusion : MitelmanSETD2/ULK4 [3p21.31/3p22.1]  [t(3;3)(p21;p22)]  
Fusion : MitelmanTRIM24/ULK4 [7q33/3p22.1]  [t(3;7)(p22;q34)]  
Fusion : MitelmanULK4/ANO10 [3p22.1/3p22.1]  [t(3;3)(p21;p22)]  
Fusion: TCGAADAMTS9 3p14.1 ULK4 3p22.1 LUAD
Fusion: TCGASETD2 3p21.31 ULK4 3p22.1 BRCA
Fusion: TCGATRIM24 7q33 ULK4 3p22.1 BRCA
Fusion: TCGAULK4 3p22.1 ANO10 3p22.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerULK4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ULK4
dbVarULK4
ClinVarULK4
1000_GenomesULK4 
Exome Variant ServerULK4
ExAC (Exome Aggregation Consortium)ULK4 (select the gene name)
Genetic variants : HAPMAP54986
Genomic Variants (DGV)ULK4 [DGVbeta]
DECIPHERULK4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisULK4 
Mutations
ICGC Data PortalULK4 
TCGA Data PortalULK4 
Broad Tumor PortalULK4
OASIS PortalULK4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDULK4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ULK4
DgiDB (Drug Gene Interaction Database)ULK4
DoCM (Curated mutations)ULK4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ULK4 (select a term)
intoGenULK4
Cancer3DULK4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617010   
Orphanet
MedgenULK4
Genetic Testing Registry ULK4
NextProtQ96C45 [Medical]
TSGene54986
GENETestsULK4
Target ValidationULK4
Huge Navigator ULK4 [HugePedia]
snp3D : Map Gene to Disease54986
BioCentury BCIQULK4
ClinGenULK4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54986
Chemical/Pharm GKB GenePA134978836
Clinical trialULK4
Miscellaneous
canSAR (ICR)ULK4 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineULK4
EVEXULK4
GoPubMedULK4
iHOPULK4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:37:26 CEST 2017

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