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UNC119 (unc-119 lipid binding chaperone)

Identity

Alias_namesunc119 (C.elegans) homolog
unc-119 homolog (C. elegans)
Alias_symbol (synonym)HRG4
POC7
POC7A
Other aliasIMD13
HGNC (Hugo) UNC119
LocusID (NCBI) 9094
Atlas_Id 53291
Location 17q11.2  [Link to chromosome band 17q11]
Location_base_pair Starts at 28546707 and ends at 28552663 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
UNC119 (17q11.2) / PNPLA2 (11p15.5)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UNC119   12565
LRG (Locus Reference Genomic)LRG_341
Cards
Entrez_Gene (NCBI)UNC119  9094  unc-119 lipid binding chaperone
AliasesHRG4; IMD13; POC7; POC7A
GeneCards (Weizmann)UNC119
Ensembl hg19 (Hinxton)ENSG00000109103 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109103 [Gene_View]  chr17:28546707-28552663 [Contig_View]  UNC119 [Vega]
ICGC DataPortalENSG00000109103
TCGA cBioPortalUNC119
AceView (NCBI)UNC119
Genatlas (Paris)UNC119
WikiGenes9094
SOURCE (Princeton)UNC119
Genetics Home Reference (NIH)UNC119
Genomic and cartography
GoldenPath hg38 (UCSC)UNC119  -     chr17:28546707-28552663 -  17q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UNC119  -     17q11.2   [Description]    (hg19-Feb_2009)
EnsemblUNC119 - 17q11.2 [CytoView hg19]  UNC119 - 17q11.2 [CytoView hg38]
Mapping of homologs : NCBIUNC119 [Mapview hg19]  UNC119 [Mapview hg38]
OMIM604011   615518   
Gene and transcription
Genbank (Entrez)AB593014 AF028788 AF028789 AK124531 AK292329
RefSeq transcript (Entrez)NM_001330166 NM_005148 NM_054035
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UNC119
Cluster EST : UnigeneHs.410455 [ NCBI ]
CGAP (NCI)Hs.410455
Alternative Splicing GalleryENSG00000109103
Gene ExpressionUNC119 [ NCBI-GEO ]   UNC119 [ EBI - ARRAY_EXPRESS ]   UNC119 [ SEEK ]   UNC119 [ MEM ]
Gene Expression Viewer (FireBrowse)UNC119 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9094
GTEX Portal (Tissue expression)UNC119
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13432   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13432  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13432
Splice isoforms : SwissVarQ13432
PhosPhoSitePlusQ13432
Domains : Interpro (EBI)Ig_E-set    PDED_dom    UNC119_homologue_A   
Domain families : Pfam (Sanger)GMP_PDE_delta (PF05351)   
Domain families : Pfam (NCBI)pfam05351   
Conserved Domain (NCBI)UNC119
DMDM Disease mutations9094
Blocks (Seattle)UNC119
PDB (SRS)3GQQ    3RBQ    4GOJ    4GOK    5L7K   
PDB (PDBSum)3GQQ    3RBQ    4GOJ    4GOK    5L7K   
PDB (IMB)3GQQ    3RBQ    4GOJ    4GOK    5L7K   
PDB (RSDB)3GQQ    3RBQ    4GOJ    4GOK    5L7K   
Structural Biology KnowledgeBase3GQQ    3RBQ    4GOJ    4GOK    5L7K   
SCOP (Structural Classification of Proteins)3GQQ    3RBQ    4GOJ    4GOK    5L7K   
CATH (Classification of proteins structures)3GQQ    3RBQ    4GOJ    4GOK    5L7K   
SuperfamilyQ13432
Human Protein AtlasENSG00000109103
Peptide AtlasQ13432
HPRD04927
IPIIPI00013262   IPI00220005   IPI00798215   
Protein Interaction databases
DIP (DOE-UCLA)Q13432
IntAct (EBI)Q13432
FunCoupENSG00000109103
BioGRIDUNC119
STRING (EMBL)UNC119
ZODIACUNC119
Ontologies - Pathways
QuickGOQ13432
Ontology : AmiGOspindle pole  protein binding  centrosome  cytosol  endocytosis  chemical synaptic transmission  visual perception  phototransduction  lipid binding  neuron differentiation  lipoprotein transport  intercellular bridge  spindle midzone  positive regulation of protein tyrosine kinase activity  negative regulation of clathrin-dependent endocytosis  negative regulation of caveolin-mediated endocytosis  
Ontology : EGO-EBIspindle pole  protein binding  centrosome  cytosol  endocytosis  chemical synaptic transmission  visual perception  phototransduction  lipid binding  neuron differentiation  lipoprotein transport  intercellular bridge  spindle midzone  positive regulation of protein tyrosine kinase activity  negative regulation of clathrin-dependent endocytosis  negative regulation of caveolin-mediated endocytosis  
NDEx NetworkUNC119
Atlas of Cancer Signalling NetworkUNC119
Wikipedia pathwaysUNC119
Orthology - Evolution
OrthoDB9094
GeneTree (enSembl)ENSG00000109103
Phylogenetic Trees/Animal Genes : TreeFamUNC119
HOVERGENQ13432
HOGENOMQ13432
Homologs : HomoloGeneUNC119
Homology/Alignments : Family Browser (UCSC)UNC119
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUNC119 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UNC119
dbVarUNC119
ClinVarUNC119
1000_GenomesUNC119 
Exome Variant ServerUNC119
ExAC (Exome Aggregation Consortium)UNC119 (select the gene name)
Genetic variants : HAPMAP9094
Genomic Variants (DGV)UNC119 [DGVbeta]
DECIPHERUNC119 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUNC119 
Mutations
ICGC Data PortalUNC119 
TCGA Data PortalUNC119 
Broad Tumor PortalUNC119
OASIS PortalUNC119 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUNC119  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUNC119
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch UNC119
DgiDB (Drug Gene Interaction Database)UNC119
DoCM (Curated mutations)UNC119 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UNC119 (select a term)
intoGenUNC119
Cancer3DUNC119(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604011    615518   
Orphanet1843    19061   
MedgenUNC119
Genetic Testing Registry UNC119
NextProtQ13432 [Medical]
TSGene9094
GENETestsUNC119
Target ValidationUNC119
Huge Navigator UNC119 [HugePedia]
snp3D : Map Gene to Disease9094
BioCentury BCIQUNC119
ClinGenUNC119
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9094
Chemical/Pharm GKB GenePA37202
Clinical trialUNC119
Miscellaneous
canSAR (ICR)UNC119 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUNC119
EVEXUNC119
GoPubMedUNC119
iHOPUNC119
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:27 CEST 2017

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