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UNC13C (unc-13 homolog C)

Identity

Alias_namesunc-13 homolog C (C. elegans)
Alias_symbol (synonym)Munc13-3
DKFZp547H074
Other alias-
HGNC (Hugo) UNC13C
LocusID (NCBI) 440279
Atlas_Id 75483
Location 15q21.3  [Link to chromosome band 15q21]
Location_base_pair Starts at 54012648 and ends at 54628608 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TRIOBP (22q13.1) / UNC13C (15q21.3)UNC13C (15q21.3) / COL1A1 (17q21.33)UNC13C (15q21.3) / NMNAT2 (1q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UNC13C   23149
Cards
Entrez_Gene (NCBI)UNC13C  440279  unc-13 homolog C
Aliases
GeneCards (Weizmann)UNC13C
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr15:54012648-54628608 [Contig_View]  UNC13C [Vega]
TCGA cBioPortalUNC13C
AceView (NCBI)UNC13C
Genatlas (Paris)UNC13C
WikiGenes440279
SOURCE (Princeton)UNC13C
Genetics Home Reference (NIH)UNC13C
Genomic and cartography
GoldenPath hg38 (UCSC)UNC13C  -     chr15:54012648-54628608 +  15q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UNC13C  -     15q21.3   [Description]    (hg19-Feb_2009)
EnsemblUNC13C - 15q21.3 [CytoView hg19]  UNC13C - 15q21.3 [CytoView hg38]
Mapping of homologs : NCBIUNC13C [Mapview hg19]  UNC13C [Mapview hg38]
OMIM614568   
Gene and transcription
Genbank (Entrez)AK054981 AK091491 AK293996 AL834407 BC036420
RefSeq transcript (Entrez)NM_001080534 NM_001329919
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UNC13C
Cluster EST : UnigeneHs.657273 [ NCBI ]
CGAP (NCI)Hs.657273
Gene ExpressionUNC13C [ NCBI-GEO ]   UNC13C [ EBI - ARRAY_EXPRESS ]   UNC13C [ SEEK ]   UNC13C [ MEM ]
Gene Expression Viewer (FireBrowse)UNC13C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)440279
GTEX Portal (Tissue expression)UNC13C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NB66   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NB66  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NB66
Splice isoforms : SwissVarQ8NB66
PhosPhoSitePlusQ8NB66
Domaine pattern : Prosite (Expaxy)C2 (PS50004)    MHD1 (PS51258)    MHD2 (PS51259)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)C2_dom    CAPS_dom    Munc13_1    Munc13_dom-2    Munc13_subgr_dom-2    PE/DAG-bd    Unc-13    Unc13C   
Domain families : Pfam (Sanger)C1_1 (PF00130)    C2 (PF00168)    DUF1041 (PF06292)    Membr_traf_MHD (PF10540)   
Domain families : Pfam (NCBI)pfam00130    pfam00168    pfam06292    pfam10540   
Domain families : Smart (EMBL)C1 (SM00109)  C2 (SM00239)  DUF1041 (SM01145)  
Conserved Domain (NCBI)UNC13C
DMDM Disease mutations440279
Blocks (Seattle)UNC13C
SuperfamilyQ8NB66
Peptide AtlasQ8NB66
IPIIPI00739565   IPI01015127   IPI01013137   IPI00786960   
Protein Interaction databases
DIP (DOE-UCLA)Q8NB66
IntAct (EBI)Q8NB66
BioGRIDUNC13C
STRING (EMBL)UNC13C
ZODIACUNC13C
Ontologies - Pathways
QuickGOQ8NB66
Ontology : AmiGOcytoplasm  plasma membrane  chemical synaptic transmission  synaptic vesicle exocytosis  diacylglycerol binding  cell junction  negative regulation of synaptic plasticity  intracellular signal transduction  presynaptic membrane  terminal bouton  calyx of Held  metal ion binding  presynaptic active zone  
Ontology : EGO-EBIcytoplasm  plasma membrane  chemical synaptic transmission  synaptic vesicle exocytosis  diacylglycerol binding  cell junction  negative regulation of synaptic plasticity  intracellular signal transduction  presynaptic membrane  terminal bouton  calyx of Held  metal ion binding  presynaptic active zone  
Pathways : KEGGSynaptic vesicle cycle   
NDEx NetworkUNC13C
Atlas of Cancer Signalling NetworkUNC13C
Wikipedia pathwaysUNC13C
Orthology - Evolution
OrthoDB440279
Phylogenetic Trees/Animal Genes : TreeFamUNC13C
HOVERGENQ8NB66
HOGENOMQ8NB66
Homologs : HomoloGeneUNC13C
Homology/Alignments : Family Browser (UCSC)UNC13C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUNC13C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UNC13C
dbVarUNC13C
ClinVarUNC13C
1000_GenomesUNC13C 
Exome Variant ServerUNC13C
ExAC (Exome Aggregation Consortium)UNC13C (select the gene name)
Genetic variants : HAPMAP440279
Genomic Variants (DGV)UNC13C [DGVbeta]
DECIPHERUNC13C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUNC13C 
Mutations
ICGC Data PortalUNC13C 
TCGA Data PortalUNC13C 
Broad Tumor PortalUNC13C
OASIS PortalUNC13C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUNC13C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUNC13C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UNC13C
DgiDB (Drug Gene Interaction Database)UNC13C
DoCM (Curated mutations)UNC13C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UNC13C (select a term)
intoGenUNC13C
Cancer3DUNC13C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614568   
Orphanet
MedgenUNC13C
Genetic Testing Registry UNC13C
NextProtQ8NB66 [Medical]
TSGene440279
GENETestsUNC13C
Target ValidationUNC13C
Huge Navigator UNC13C [HugePedia]
snp3D : Map Gene to Disease440279
BioCentury BCIQUNC13C
ClinGenUNC13C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD440279
Chemical/Pharm GKB GenePA134870087
Clinical trialUNC13C
Miscellaneous
canSAR (ICR)UNC13C (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUNC13C
EVEXUNC13C
GoPubMedUNC13C
iHOPUNC13C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:43:16 CEST 2017

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