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UNC45A (unc-45 myosin chaperone A)

Identity

Alias_namesunc-45 homolog A (C. elegans)
Alias_symbol (synonym)SMAP-1
GC-UNC45
Other aliasGCUNC-45
GCUNC45
IRO039700
SMAP1
UNC-45A
HGNC (Hugo) UNC45A
LocusID (NCBI) 55898
Atlas_Id 50036
Location 15q26.1  [Link to chromosome band 15q26]
Location_base_pair Starts at 90930180 and ends at 90954093 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
UNC45A (15q26.1) / IQGAP1 (15q26.1)UNC45A 15q26.1 / IQGAP1 15q26.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UNC45A   30594
Cards
Entrez_Gene (NCBI)UNC45A  55898  unc-45 myosin chaperone A
AliasesGC-UNC45; GCUNC-45; GCUNC45; IRO039700; 
SMAP-1; SMAP1; UNC-45A
GeneCards (Weizmann)UNC45A
Ensembl hg19 (Hinxton)ENSG00000140553 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140553 [Gene_View]  chr15:90930180-90954093 [Contig_View]  UNC45A [Vega]
ICGC DataPortalENSG00000140553
TCGA cBioPortalUNC45A
AceView (NCBI)UNC45A
Genatlas (Paris)UNC45A
WikiGenes55898
SOURCE (Princeton)UNC45A
Genetics Home Reference (NIH)UNC45A
Genomic and cartography
GoldenPath hg38 (UCSC)UNC45A  -     chr15:90930180-90954093 +  15q26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UNC45A  -     15q26.1   [Description]    (hg19-Feb_2009)
EnsemblUNC45A - 15q26.1 [CytoView hg19]  UNC45A - 15q26.1 [CytoView hg38]
Mapping of homologs : NCBIUNC45A [Mapview hg19]  UNC45A [Mapview hg38]
OMIM611219   
Gene and transcription
Genbank (Entrez)AB014729 AB014736 AK000905 AK125523 AK125721
RefSeq transcript (Entrez)NM_001039675 NM_001323619 NM_001323620 NM_001323621 NM_017979 NM_018671
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UNC45A
Cluster EST : UnigeneHs.389461 [ NCBI ]
CGAP (NCI)Hs.389461
Alternative Splicing GalleryENSG00000140553
Gene ExpressionUNC45A [ NCBI-GEO ]   UNC45A [ EBI - ARRAY_EXPRESS ]   UNC45A [ SEEK ]   UNC45A [ MEM ]
Gene Expression Viewer (FireBrowse)UNC45A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55898
GTEX Portal (Tissue expression)UNC45A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3U1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H3U1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H3U1
Splice isoforms : SwissVarQ9H3U1
PhosPhoSitePlusQ9H3U1
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    TPR-contain_dom    TPR-like_helical_dom    TPR_repeat    UCS_central_dom   
Domain families : Pfam (Sanger)TPR_8 (PF13181)    UNC45-central (PF11701)   
Domain families : Pfam (NCBI)pfam13181    pfam11701   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)UNC45A
DMDM Disease mutations55898
Blocks (Seattle)UNC45A
PDB (SRS)2DBA   
PDB (PDBSum)2DBA   
PDB (IMB)2DBA   
PDB (RSDB)2DBA   
Structural Biology KnowledgeBase2DBA   
SCOP (Structural Classification of Proteins)2DBA   
CATH (Classification of proteins structures)2DBA   
SuperfamilyQ9H3U1
Human Protein AtlasENSG00000140553
Peptide AtlasQ9H3U1
HPRD18070
IPIIPI00072534   IPI00735181   IPI00788016   IPI00908569   IPI00909477   IPI00017446   
Protein Interaction databases
DIP (DOE-UCLA)Q9H3U1
IntAct (EBI)Q9H3U1
FunCoupENSG00000140553
BioGRIDUNC45A
STRING (EMBL)UNC45A
ZODIACUNC45A
Ontologies - Pathways
QuickGOQ9H3U1
Ontology : AmiGOprotein binding  Golgi apparatus  cytosol  muscle organ development  nuclear speck  cell differentiation  cadherin binding  perinuclear region of cytoplasm  Hsp90 protein binding  chaperone-mediated protein folding  
Ontology : EGO-EBIprotein binding  Golgi apparatus  cytosol  muscle organ development  nuclear speck  cell differentiation  cadherin binding  perinuclear region of cytoplasm  Hsp90 protein binding  chaperone-mediated protein folding  
NDEx NetworkUNC45A
Atlas of Cancer Signalling NetworkUNC45A
Wikipedia pathwaysUNC45A
Orthology - Evolution
OrthoDB55898
GeneTree (enSembl)ENSG00000140553
Phylogenetic Trees/Animal Genes : TreeFamUNC45A
HOVERGENQ9H3U1
HOGENOMQ9H3U1
Homologs : HomoloGeneUNC45A
Homology/Alignments : Family Browser (UCSC)UNC45A
Gene fusions - Rearrangements
Fusion : MitelmanUNC45A/IQGAP1 [15q26.1/15q26.1]  
Fusion: TCGAUNC45A 15q26.1 IQGAP1 15q26.1 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUNC45A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UNC45A
dbVarUNC45A
ClinVarUNC45A
1000_GenomesUNC45A 
Exome Variant ServerUNC45A
ExAC (Exome Aggregation Consortium)UNC45A (select the gene name)
Genetic variants : HAPMAP55898
Genomic Variants (DGV)UNC45A [DGVbeta]
DECIPHERUNC45A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUNC45A 
Mutations
ICGC Data PortalUNC45A 
TCGA Data PortalUNC45A 
Broad Tumor PortalUNC45A
OASIS PortalUNC45A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUNC45A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUNC45A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UNC45A
DgiDB (Drug Gene Interaction Database)UNC45A
DoCM (Curated mutations)UNC45A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UNC45A (select a term)
intoGenUNC45A
Cancer3DUNC45A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611219   
Orphanet
MedgenUNC45A
Genetic Testing Registry UNC45A
NextProtQ9H3U1 [Medical]
TSGene55898
GENETestsUNC45A
Huge Navigator UNC45A [HugePedia]
snp3D : Map Gene to Disease55898
BioCentury BCIQUNC45A
ClinGenUNC45A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55898
Chemical/Pharm GKB GenePA142670638
Clinical trialUNC45A
Miscellaneous
canSAR (ICR)UNC45A (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUNC45A
EVEXUNC45A
GoPubMedUNC45A
iHOPUNC45A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:43:23 CEST 2017

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