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UNC5CL (unc-5 family C-terminal like)

Identity

Other aliasMUXA
ZUD
HGNC (Hugo) UNC5CL
LocusID (NCBI) 222643
Atlas_Id 56918
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41026901 and ends at 41039199 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CALM1 (14q32.11) / UNC5CL (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UNC5CL   21203
Cards
Entrez_Gene (NCBI)UNC5CL  222643  unc-5 family C-terminal like
AliasesMUXA; ZUD
GeneCards (Weizmann)UNC5CL
Ensembl hg19 (Hinxton)ENSG00000124602 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124602 [Gene_View]  ENSG00000124602 [Sequence]  chr6:41026901-41039199 [Contig_View]  UNC5CL [Vega]
ICGC DataPortalENSG00000124602
TCGA cBioPortalUNC5CL
AceView (NCBI)UNC5CL
Genatlas (Paris)UNC5CL
WikiGenes222643
SOURCE (Princeton)UNC5CL
Genetics Home Reference (NIH)UNC5CL
Genomic and cartography
GoldenPath hg38 (UCSC)UNC5CL  -     chr6:41026901-41039199 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UNC5CL  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblUNC5CL - 6p21.1 [CytoView hg19]  UNC5CL - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIUNC5CL [Mapview hg19]  UNC5CL [Mapview hg38]
OMIM617464   
Gene and transcription
Genbank (Entrez)AI791395 AY510109 BC035284 BM312066 JF681947
RefSeq transcript (Entrez)NM_173561
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UNC5CL
Cluster EST : UnigeneHs.158357 [ NCBI ]
CGAP (NCI)Hs.158357
Alternative Splicing GalleryENSG00000124602
Gene ExpressionUNC5CL [ NCBI-GEO ]   UNC5CL [ EBI - ARRAY_EXPRESS ]   UNC5CL [ SEEK ]   UNC5CL [ MEM ]
Gene Expression Viewer (FireBrowse)UNC5CL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222643
GTEX Portal (Tissue expression)UNC5CL
Human Protein AtlasENSG00000124602-UNC5CL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IV45   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IV45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IV45
Splice isoforms : SwissVarQ8IV45
PhosPhoSitePlusQ8IV45
Domaine pattern : Prosite (Expaxy)DEATH_DOMAIN (PS50017)    ZU5 (PS51145)   
Domains : Interpro (EBI)DEATH-like_dom_sf    Death_domain    UNC5    UPA    ZU5_dom   
Domain families : Pfam (Sanger)Death (PF00531)    UPA (PF17217)    ZU5 (PF00791)   
Domain families : Pfam (NCBI)pfam00531    pfam17217    pfam00791   
Domain families : Smart (EMBL)DEATH (SM00005)  ZU5 (SM00218)  
Conserved Domain (NCBI)UNC5CL
DMDM Disease mutations222643
Blocks (Seattle)UNC5CL
SuperfamilyQ8IV45
Human Protein Atlas [tissue]ENSG00000124602-UNC5CL [tissue]
Peptide AtlasQ8IV45
IPIIPI00216869   
Protein Interaction databases
DIP (DOE-UCLA)Q8IV45
IntAct (EBI)Q8IV45
FunCoupENSG00000124602
BioGRIDUNC5CL
STRING (EMBL)UNC5CL
ZODIACUNC5CL
Ontologies - Pathways
QuickGOQ8IV45
Ontology : AmiGOnetrin receptor activity  cytoplasm  proteolysis  peptidase activity  membrane  integral component of membrane  netrin-activated signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of JNK cascade  
Ontology : EGO-EBInetrin receptor activity  cytoplasm  proteolysis  peptidase activity  membrane  integral component of membrane  netrin-activated signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of JNK cascade  
NDEx NetworkUNC5CL
Atlas of Cancer Signalling NetworkUNC5CL
Wikipedia pathwaysUNC5CL
Orthology - Evolution
OrthoDB222643
GeneTree (enSembl)ENSG00000124602
Phylogenetic Trees/Animal Genes : TreeFamUNC5CL
HOVERGENQ8IV45
HOGENOMQ8IV45
Homologs : HomoloGeneUNC5CL
Homology/Alignments : Family Browser (UCSC)UNC5CL
Gene fusions - Rearrangements
Fusion : QuiverUNC5CL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUNC5CL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UNC5CL
dbVarUNC5CL
ClinVarUNC5CL
1000_GenomesUNC5CL 
Exome Variant ServerUNC5CL
ExAC (Exome Aggregation Consortium)ENSG00000124602
GNOMAD BrowserENSG00000124602
Varsome BrowserUNC5CL
Genetic variants : HAPMAP222643
Genomic Variants (DGV)UNC5CL [DGVbeta]
DECIPHERUNC5CL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUNC5CL 
Mutations
ICGC Data PortalUNC5CL 
TCGA Data PortalUNC5CL 
Broad Tumor PortalUNC5CL
OASIS PortalUNC5CL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUNC5CL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUNC5CL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UNC5CL
DgiDB (Drug Gene Interaction Database)UNC5CL
DoCM (Curated mutations)UNC5CL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UNC5CL (select a term)
intoGenUNC5CL
Cancer3DUNC5CL(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617464   
Orphanet
DisGeNETUNC5CL
MedgenUNC5CL
Genetic Testing Registry UNC5CL
NextProtQ8IV45 [Medical]
TSGene222643
GENETestsUNC5CL
Target ValidationUNC5CL
Huge Navigator UNC5CL [HugePedia]
snp3D : Map Gene to Disease222643
BioCentury BCIQUNC5CL
ClinGenUNC5CL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222643
Chemical/Pharm GKB GenePA134906657
Clinical trialUNC5CL
Miscellaneous
canSAR (ICR)UNC5CL (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUNC5CL
EVEXUNC5CL
GoPubMedUNC5CL
iHOPUNC5CL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:48:42 CET 2018

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