Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

UNG (uracil-DNA glycosylase)

Identity

Other namesDGU
HIGM4
HIGM5
UDG
UNG1
UNG15
UNG2
HGNC (Hugo) UNG
LocusID (NCBI) 7374
Location 12q24.11
Location_base_pair Starts at 109535923 and ends at 109548798 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)UNG   12572
Cards
Entrez_Gene (NCBI)UNG  7374  uracil-DNA glycosylase
GeneCards (Weizmann)UNG
Ensembl (Hinxton)ENSG00000076248 [Gene_View]  chr12:109535923-109548798 [Contig_View]  UNG [Vega]
ICGC DataPortalENSG00000076248
AceView (NCBI)UNG
Genatlas (Paris)UNG
WikiGenes7374
SOURCE (Princeton)NM_003362 NM_080911
Genomic and cartography
GoldenPath (UCSC)UNG  -  12q24.11   chr12:109535923-109548798 +  12q24.11   [Description]    (hg19-Feb_2009)
EnsemblUNG - 12q24.11 [CytoView]
Mapping of homologs : NCBIUNG [Mapview]
OMIM191525   608106   
Gene and transcription
Genbank (Entrez)AK291341 AK299416 AK313552 BC015205 BC050634
RefSeq transcript (Entrez)NM_003362 NM_080911
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_007284 NT_029419 NW_001838062 NW_004929385
Consensus coding sequences : CCDS (NCBI)UNG
Cluster EST : UnigeneHs.191334 [ NCBI ]
CGAP (NCI)Hs.191334
Alternative Splicing : Fast-db (Paris)GSHG0006987
Alternative Splicing GalleryENSG00000076248
Gene ExpressionUNG [ NCBI-GEO ]     UNG [ SEEK ]   UNG [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13051 (Uniprot)
NextProtP13051  [Medical]
With graphics : InterProP13051
Splice isoforms : SwissVarP13051 (Swissvar)
Domaine pattern : Prosite (Expaxy)U_DNA_GLYCOSYLASE (PS00130)   
Domains : Interpro (EBI)Ura-DNA_Glyclase_AS    Ura_DNA_glycsylse    Uracil-DNA_glycosylase-like   
Related proteins : CluSTrP13051
Domain families : Pfam (Sanger)UDG (PF03167)   
Domain families : Pfam (NCBI)pfam03167   
Domain families : Smart (EMBL)UDG (SM00986)  
DMDM Disease mutations7374
Blocks (Seattle)P13051
PDB (SRS)1AKZ    1DPU    1EMH    1EMJ    1Q3F    1SSP    1UGH    1YUO    2HXM    2OXM    2OYT    2SSP    3FCF    3FCI    3FCK    3FCL    3TKB    4SKN   
PDB (PDBSum)1AKZ    1DPU    1EMH    1EMJ    1Q3F    1SSP    1UGH    1YUO    2HXM    2OXM    2OYT    2SSP    3FCF    3FCI    3FCK    3FCL    3TKB    4SKN   
PDB (IMB)1AKZ    1DPU    1EMH    1EMJ    1Q3F    1SSP    1UGH    1YUO    2HXM    2OXM    2OYT    2SSP    3FCF    3FCI    3FCK    3FCL    3TKB    4SKN   
PDB (RSDB)1AKZ    1DPU    1EMH    1EMJ    1Q3F    1SSP    1UGH    1YUO    2HXM    2OXM    2OYT    2SSP    3FCF    3FCI    3FCK    3FCL    3TKB    4SKN   
Human Protein AtlasENSG00000076248
Peptide AtlasP13051
HPRD01881
IPIIPI00011069   IPI00006516   IPI00909037   IPI01012179   IPI01010925   IPI01011729   
Protein Interaction databases
DIP (DOE-UCLA)P13051
IntAct (EBI)P13051
FunCoupENSG00000076248
BioGRIDUNG
InParanoidP13051
Interologous Interaction database P13051
IntegromeDBUNG
STRING (EMBL)UNG
Ontologies - Pathways
Ontology : AmiGOuracil DNA N-glycosylase activity  nucleus  mitochondrion  DNA repair  base-excision repair  viral process  somatic hypermutation of immunoglobulin genes  somatic recombination of immunoglobulin gene segments  negative regulation of apoptotic process  
Ontology : EGO-EBIuracil DNA N-glycosylase activity  nucleus  mitochondrion  DNA repair  base-excision repair  viral process  somatic hypermutation of immunoglobulin genes  somatic recombination of immunoglobulin gene segments  negative regulation of apoptotic process  
Pathways : KEGGBase excision repair    Primary immunodeficiency   
Protein Interaction DatabaseUNG
Wikipedia pathwaysUNG
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)UNG
SNP (GeneSNP Utah)UNG
SNP : HGBaseUNG
Genetic variants : HAPMAPUNG
1000_GenomesUNG 
ICGC programENSG00000076248 
CONAN: Copy Number AnalysisUNG 
Somatic Mutations in Cancer : COSMICUNG 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Mutations and Diseases : HGMDUNG
OMIM191525    608106   
MedgenUNG
GENETestsUNG
Disease Genetic AssociationUNG
Huge Navigator UNG [HugePedia]  UNG [HugeCancerGEM]
Genomic VariantsUNG  UNG [DGVbeta]
Exome VariantUNG
dbVarUNG
ClinVarUNG
snp3D : Map Gene to Disease7374
General knowledge
Homologs : HomoloGeneUNG
Homology/Alignments : Family Browser (UCSC)UNG
Phylogenetic Trees/Animal Genes : TreeFamUNG
Chemical/Protein Interactions : CTD7374
Chemical/Pharm GKB GenePA364
Clinical trialUNG
Cancer Resource (Charite)ENSG00000076248
Other databases
Probes
Litterature
PubMed145 Pubmed reference(s) in Entrez
CoreMineUNG
iHOPUNG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:25:12 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.