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UNKL (unkempt family like zinc finger)

Identity

Alias_namesC16orf28
chromosome 16 open reading frame 28
unkempt homolog (Drosophila)-like
unkempt family zinc finger-like
Alias_symbol (synonym)ZC3HDC5L
ZC3H5L
FLJ23360
Other alias
HGNC (Hugo) UNKL
LocusID (NCBI) 64718
Atlas_Id 75492
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 1398305 and ends at 1414720 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CRYAB (11q23.1) / UNKL (16p13.3)UNKL (16p13.3) / CLCN7 (16p13.3)UNKL (16p13.3) / PANX2 (22q13.33)
UNKL (16p13.3) / TJP1 (15q13.1)UNKL (16p13.3) / UNKL (16p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UNKL   14184
Cards
Entrez_Gene (NCBI)UNKL  64718  unkempt family like zinc finger
AliasesC16orf28; ZC3H5L; ZC3HDC5L
GeneCards (Weizmann)UNKL
Ensembl hg19 (Hinxton)ENSG00000059145 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000059145 [Gene_View]  chr16:1398305-1414720 [Contig_View]  UNKL [Vega]
ICGC DataPortalENSG00000059145
TCGA cBioPortalUNKL
AceView (NCBI)UNKL
Genatlas (Paris)UNKL
WikiGenes64718
SOURCE (Princeton)UNKL
Genetics Home Reference (NIH)UNKL
Genomic and cartography
GoldenPath hg38 (UCSC)UNKL  -     chr16:1398305-1414720 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UNKL  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblUNKL - 16p13.3 [CytoView hg19]  UNKL - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIUNKL [Mapview hg19]  UNKL [Mapview hg38]
OMIM617463   
Gene and transcription
Genbank (Entrez)AK022685 AK024842 AK027013 AK124977 AM944365
RefSeq transcript (Entrez)NM_001037125 NM_001193388 NM_001193389 NM_001276414 NM_023076
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UNKL
Cluster EST : UnigeneHs.745452 [ NCBI ]
CGAP (NCI)Hs.745452
Alternative Splicing GalleryENSG00000059145
Gene ExpressionUNKL [ NCBI-GEO ]   UNKL [ EBI - ARRAY_EXPRESS ]   UNKL [ SEEK ]   UNKL [ MEM ]
Gene Expression Viewer (FireBrowse)UNKL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64718
GTEX Portal (Tissue expression)UNKL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H9P5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H9P5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H9P5
Splice isoforms : SwissVarQ9H9P5
Catalytic activity : Enzyme2.3.2.- [ Enzyme-Expasy ]   2.3.2.-2.3.2.- [ IntEnz-EBI ]   2.3.2.- [ BRENDA ]   2.3.2.- [ KEGG ]   
PhosPhoSitePlusQ9H9P5
Domaine pattern : Prosite (Expaxy)ZF_C3H1 (PS50103)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_CCCH    Znf_RING   
Domain families : Pfam (Sanger)zf-CCCH (PF00642)   
Domain families : Pfam (NCBI)pfam00642   
Domain families : Smart (EMBL)ZnF_C3H1 (SM00356)  
Conserved Domain (NCBI)UNKL
DMDM Disease mutations64718
Blocks (Seattle)UNKL
SuperfamilyQ9H9P5
Human Protein AtlasENSG00000059145
Peptide AtlasQ9H9P5
HPRD15612
IPIIPI00877778   IPI00008401   IPI00074829   IPI00969183   IPI00061757   IPI00045532   IPI01013227   IPI00965104   
Protein Interaction databases
DIP (DOE-UCLA)Q9H9P5
IntAct (EBI)Q9H9P5
FunCoupENSG00000059145
BioGRIDUNKL
STRING (EMBL)UNKL
ZODIACUNKL
Ontologies - Pathways
QuickGOQ9H9P5
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  cytosol  cytosol  zinc ion binding  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  cytosol  cytosol  zinc ion binding  
NDEx NetworkUNKL
Atlas of Cancer Signalling NetworkUNKL
Wikipedia pathwaysUNKL
Orthology - Evolution
OrthoDB64718
GeneTree (enSembl)ENSG00000059145
Phylogenetic Trees/Animal Genes : TreeFamUNKL
HOVERGENQ9H9P5
HOGENOMQ9H9P5
Homologs : HomoloGeneUNKL
Homology/Alignments : Family Browser (UCSC)UNKL
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUNKL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UNKL
dbVarUNKL
ClinVarUNKL
1000_GenomesUNKL 
Exome Variant ServerUNKL
ExAC (Exome Aggregation Consortium)UNKL (select the gene name)
Genetic variants : HAPMAP64718
Genomic Variants (DGV)UNKL [DGVbeta]
DECIPHERUNKL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUNKL 
Mutations
ICGC Data PortalUNKL 
TCGA Data PortalUNKL 
Broad Tumor PortalUNKL
OASIS PortalUNKL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUNKL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUNKL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UNKL
DgiDB (Drug Gene Interaction Database)UNKL
DoCM (Curated mutations)UNKL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UNKL (select a term)
intoGenUNKL
Cancer3DUNKL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617463   
Orphanet
MedgenUNKL
Genetic Testing Registry UNKL
NextProtQ9H9P5 [Medical]
TSGene64718
GENETestsUNKL
Target ValidationUNKL
Huge Navigator UNKL [HugePedia]
snp3D : Map Gene to Disease64718
BioCentury BCIQUNKL
ClinGenUNKL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64718
Chemical/Pharm GKB GenePA37855
Clinical trialUNKL
Miscellaneous
canSAR (ICR)UNKL (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUNKL
EVEXUNKL
GoPubMedUNKL
iHOPUNKL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:48:13 CEST 2017

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