| CLASP1 (2q14.2) / UPF2 (10p14) | ENY2 (8q23.1) / UPF2 (10p14) | MIR100HG (11q24.1) / UPF2 (10p14) |
|
PPP2R5C (14q32.31) / UPF2 (10p14) | UPF2 (10p14) / GLUD1 (10q23.2) | UPF2 (10p14) / LUM (12q21.33) |
|
UPF2 (10p14) / MTAP (9p21.3) | USP32 (17q23.1) / UPF2 (10p14) | USP6NL (10p14) / UPF2 (10p14) |
|
| Nomenclature |
HGNC (Hugo) | UPF2 17854 |
| Cards |
Entrez_Gene (NCBI) | UPF2 UPF2 regulator of nonsense mediated mRNA decay |
Aliases | HUPF2; RENT2; smg-3 |
GeneCards (Weizmann) | UPF2 |
Ensembl hg19 (Hinxton) | ENSG00000151461 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000151461 [Gene_View]  ENSG00000151461 [Sequence] chr10:11920022-12043170 [Contig_View] UPF2 [Vega] |
ICGC DataPortal | ENSG00000151461 |
TCGA cBioPortal | UPF2 |
AceView (NCBI) | UPF2 |
Genatlas (Paris) | UPF2 |
SOURCE (Princeton) | UPF2 |
Genetics Home Reference (NIH) | UPF2 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | UPF2 - chr10:11920022-12043170 - 10p14 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | UPF2 - 10p14 [Description] (hg19-Feb_2009) |
GoldenPath | UPF2 - 10p14 [CytoView hg19] UPF2 - 10p14 [CytoView hg38] |
ImmunoBase | ENSG00000151461 |
genome Data Viewer NCBI | UPF2 [Mapview hg19] |
OMIM | 605529 |
| Gene and transcription |
Genbank (Entrez) | AB037829 AF301013 AF318574 AK000764 AK074375 |
RefSeq transcript (Entrez) | NM_015542 NM_080599 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | UPF2 |
Alternative Splicing Gallery | ENSG00000151461 |
Gene Expression | UPF2 [ NCBI-GEO ] UPF2 [ EBI - ARRAY_EXPRESS ]
UPF2 [ SEEK ] UPF2 [ MEM ] |
Gene Expression Viewer (FireBrowse) | UPF2 [ Firebrowse - Broad ] |
Genevisible | Expression of UPF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 26019 |
GTEX Portal (Tissue expression) | UPF2 |
Human Protein Atlas | ENSG00000151461-UPF2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q9HAU5 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q9HAU5 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q9HAU5 |
Splice isoforms : SwissVar | Q9HAU5 |
PhosPhoSitePlus | Q9HAU5 |
Domains : Interpro (EBI) | ARM-type_fold MIF4-like_sf MIF4G-like_typ-3 Nmd2/UPF2 Upf2/Nmd2_C |
Domain families : Pfam (Sanger) | MIF4G (PF02854) Upf2 (PF04050) |
Domain families : Pfam (NCBI) | pfam02854 pfam04050 |
Domain families : Smart (EMBL) | MIF4G (SM00543) |
Conserved Domain (NCBI) | UPF2 |
Blocks (Seattle) | UPF2 |
PDB (RSDB) | 1UW4 2WJV 4CEK 4CEM |
PDB Europe | 1UW4 2WJV 4CEK 4CEM |
PDB (PDBSum) | 1UW4 2WJV 4CEK 4CEM |
PDB (IMB) | 1UW4 2WJV 4CEK 4CEM |
Structural Biology KnowledgeBase | 1UW4 2WJV 4CEK 4CEM |
SCOP (Structural Classification of Proteins) | 1UW4 2WJV 4CEK 4CEM |
CATH (Classification of proteins structures) | 1UW4 2WJV 4CEK 4CEM |
Superfamily | Q9HAU5 |
Human Protein Atlas [tissue] | ENSG00000151461-UPF2 [tissue] |
Peptide Atlas | Q9HAU5 |
HPRD | 10405 |
IPI | IPI00300504 IPI00472081 IPI00556093 IPI00152670 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q9HAU5 |
IntAct (EBI) | Q9HAU5 |
BioGRID | UPF2 |
STRING (EMBL) | UPF2 |
ZODIAC | UPF2 |
| Ontologies - Pathways |
QuickGO | Q9HAU5 |
Ontology : AmiGO | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay liver development RNA binding protein binding nucleus cytoplasm cytoplasm cytosol cytosol polysome mRNA export from nucleus animal organ regeneration exon-exon junction complex exon-exon junction complex cytoplasmic ribonucleoprotein granule telomeric DNA binding perinuclear region of cytoplasm |
Ontology : EGO-EBI | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay liver development RNA binding protein binding nucleus cytoplasm cytoplasm cytosol cytosol polysome mRNA export from nucleus animal organ regeneration exon-exon junction complex exon-exon junction complex cytoplasmic ribonucleoprotein granule telomeric DNA binding perinuclear region of cytoplasm |
NDEx Network | UPF2 |
Atlas of Cancer Signalling Network | UPF2 |
Wikipedia pathways | UPF2 |
| Orthology - Evolution |
OrthoDB | 26019 |
GeneTree (enSembl) | ENSG00000151461 |
Phylogenetic Trees/Animal Genes : TreeFam | UPF2 |
HOGENOM | Q9HAU5 |
Homologs : HomoloGene | UPF2 |
Homology/Alignments : Family Browser (UCSC) | UPF2 |
| Gene fusions - Rearrangements |
Fusion : Quiver | UPF2 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | UPF2 [hg38] |
dbVar | UPF2 |
ClinVar | UPF2 |
Monarch | UPF2 |
1000_Genomes | UPF2 |
Exome Variant Server | UPF2 |
GNOMAD Browser | ENSG00000151461 |
Varsome Browser | UPF2 |
Genomic Variants (DGV) | UPF2 [DGVbeta] |
DECIPHER | UPF2 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | UPF2 |
| Mutations |
ICGC Data Portal | UPF2 |
TCGA Data Portal | UPF2 |
Broad Tumor Portal | UPF2 |
OASIS Portal | UPF2 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | UPF2 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | UPF2 |
Mutations and Diseases : HGMD | UPF2 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search UPF2 |
DgiDB (Drug Gene Interaction Database) | UPF2 |
DoCM (Curated mutations) | UPF2 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | UPF2 (select a term) |
intoGen | UPF2 |
Cancer3D | UPF2(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 605529 |
Orphanet | |
DisGeNET | UPF2 |
Medgen | UPF2 |
Genetic Testing Registry | UPF2
|
NextProt | Q9HAU5 [Medical] |
GENETests | UPF2 |
Target Validation | UPF2 |
Huge Navigator |
UPF2 [HugePedia] |
ClinGen | UPF2 |
| Clinical trials, drugs, therapy |
---|
MyCancerGenome | UPF2 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA134945630 |
Clinical trial | UPF2 |
| Miscellaneous |
---|
canSAR (ICR) | UPF2 (select the gene name) |
Harmonizome | UPF2 |
DataMed Index | UPF2 |
| Probes |
---|
| Litterature |
---|
PubMed | 75 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | UPF2 |
EVEX | UPF2 |
GoPubMed | UPF2 |