UPK3A (uroplakin 3A)

2007-02-01  

Identity

HGNC
LOCATION
22q13.31
LOCUSID
ALIAS
UP3A,UPIII,UPIIIA,UPK3
FUSION GENES

Other Information

Locus ID:

NCBI: 7380
MIM: 611559
HGNC: 12580
Ensembl: ENSG00000100373

Variants:

dbSNP: 7380
ClinVar: 7380
TCGA: ENSG00000100373
COSMIC: UPK3A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100373ENST00000216211O75631
ENSG00000100373ENST00000396082O75631

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Bladder cancerKEGGko05219
Bladder cancerKEGGhsa05219

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
357740822022High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway.1
357740822022High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway.1
300694822018Uroplakin IIIa Is a Marker in Bladder Cancer but Seems Not to Reflect Chemical Carcinogenesis.3
300694822018Uroplakin IIIa Is a Marker in Bladder Cancer but Seems Not to Reflect Chemical Carcinogenesis.3
257438282015High expression level of preoperative serum Uroplakin III is associated with biologically aggressive bladder cancer.3
257438282015High expression level of preoperative serum Uroplakin III is associated with biologically aggressive bladder cancer.3
245533012014Significance of uroplakin III expression in recurrence of solitary muscle non-invasive bladder cancer.1
253682912014Value of uroplakin III in distinguishing variants of primary bladder urothelial carcinoma from malignancy metastatic to the urinary bladder.1
245533012014Significance of uroplakin III expression in recurrence of solitary muscle non-invasive bladder cancer.1
253682912014Value of uroplakin III in distinguishing variants of primary bladder urothelial carcinoma from malignancy metastatic to the urinary bladder.1
199597182010Whole-genome linkage and association scan in primary, nonsyndromic vesicoureteric reflux.23
199597182010Whole-genome linkage and association scan in primary, nonsyndromic vesicoureteric reflux.23
190079072009Differentiation-induced uroplakin III expression promotes urothelial cell death in response to uropathogenic E. coli.23
194123412009Bacteria-induced uroplakin signaling mediates bladder response to infection.84
190079072009Differentiation-induced uroplakin III expression promotes urothelial cell death in response to uropathogenic E. coli.23

Citation

Dessen P

UPK3A (uroplakin 3A)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46005/upk3a