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UPP2 (uridine phosphorylase 2)

Identity

Alias_symbol (synonym)UPASE2
UP2
UDRPASE2
Other alias
HGNC (Hugo) UPP2
LocusID (NCBI) 151531
Atlas_Id 75500
Location 2q24.1  [Link to chromosome band 2q24]
Location_base_pair Starts at 157995179 and ends at 158136154 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UPP2   23061
Cards
Entrez_Gene (NCBI)UPP2  151531  uridine phosphorylase 2
AliasesUDRPASE2; UP2; UPASE2
GeneCards (Weizmann)UPP2
Ensembl hg19 (Hinxton)ENSG00000007001 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000007001 [Gene_View]  chr2:157995179-158136154 [Contig_View]  UPP2 [Vega]
ICGC DataPortalENSG00000007001
TCGA cBioPortalUPP2
AceView (NCBI)UPP2
Genatlas (Paris)UPP2
WikiGenes151531
SOURCE (Princeton)UPP2
Genetics Home Reference (NIH)UPP2
Genomic and cartography
GoldenPath hg38 (UCSC)UPP2  -     chr2:157995179-158136154 +  2q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UPP2  -     2q24.1   [Description]    (hg19-Feb_2009)
EnsemblUPP2 - 2q24.1 [CytoView hg19]  UPP2 - 2q24.1 [CytoView hg38]
Mapping of homologs : NCBIUPP2 [Mapview hg19]  UPP2 [Mapview hg38]
OMIM617340   
Gene and transcription
Genbank (Entrez)AA995921 AK122743 AW771260 AY225131 BC033529
RefSeq transcript (Entrez)NM_001135098 NM_173355
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UPP2
Cluster EST : UnigeneHs.128427 [ NCBI ]
CGAP (NCI)Hs.128427
Alternative Splicing GalleryENSG00000007001
Gene ExpressionUPP2 [ NCBI-GEO ]   UPP2 [ EBI - ARRAY_EXPRESS ]   UPP2 [ SEEK ]   UPP2 [ MEM ]
Gene Expression Viewer (FireBrowse)UPP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151531
GTEX Portal (Tissue expression)UPP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95045   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95045  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95045
Splice isoforms : SwissVarO95045
PhosPhoSitePlusO95045
Domaine pattern : Prosite (Expaxy)PNP_UDP_1 (PS01232)   
Domains : Interpro (EBI)Nucleoside_phosphorylase_CS    Nucleoside_phosphorylase_d    Uridine_phosphorylase_euk   
Domain families : Pfam (Sanger)PNP_UDP_1 (PF01048)   
Domain families : Pfam (NCBI)pfam01048   
Conserved Domain (NCBI)UPP2
DMDM Disease mutations151531
Blocks (Seattle)UPP2
PDB (SRS)2XRF    3P0E    3P0F   
PDB (PDBSum)2XRF    3P0E    3P0F   
PDB (IMB)2XRF    3P0E    3P0F   
PDB (RSDB)2XRF    3P0E    3P0F   
Structural Biology KnowledgeBase2XRF    3P0E    3P0F   
SCOP (Structural Classification of Proteins)2XRF    3P0E    3P0F   
CATH (Classification of proteins structures)2XRF    3P0E    3P0F   
SuperfamilyO95045
Human Protein AtlasENSG00000007001
Peptide AtlasO95045
HPRD15627
IPIIPI00098522   IPI00913892   
Protein Interaction databases
DIP (DOE-UCLA)O95045
IntAct (EBI)O95045
FunCoupENSG00000007001
BioGRIDUPP2
STRING (EMBL)UPP2
ZODIACUPP2
Ontologies - Pathways
QuickGOO95045
Ontology : AmiGOuridine phosphorylase activity  uridine phosphorylase activity  protein binding  cytosol  cytosol  nucleoside metabolic process  nucleotide catabolic process  pyrimidine nucleoside salvage  UMP salvage  type III intermediate filament  uridine metabolic process  pyrimidine nucleoside catabolic process  
Ontology : EGO-EBIuridine phosphorylase activity  uridine phosphorylase activity  protein binding  cytosol  cytosol  nucleoside metabolic process  nucleotide catabolic process  pyrimidine nucleoside salvage  UMP salvage  type III intermediate filament  uridine metabolic process  pyrimidine nucleoside catabolic process  
Pathways : KEGGPyrimidine metabolism    Drug metabolism - other enzymes   
NDEx NetworkUPP2
Atlas of Cancer Signalling NetworkUPP2
Wikipedia pathwaysUPP2
Orthology - Evolution
OrthoDB151531
GeneTree (enSembl)ENSG00000007001
Phylogenetic Trees/Animal Genes : TreeFamUPP2
HOVERGENO95045
HOGENOMO95045
Homologs : HomoloGeneUPP2
Homology/Alignments : Family Browser (UCSC)UPP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUPP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UPP2
dbVarUPP2
ClinVarUPP2
1000_GenomesUPP2 
Exome Variant ServerUPP2
ExAC (Exome Aggregation Consortium)UPP2 (select the gene name)
Genetic variants : HAPMAP151531
Genomic Variants (DGV)UPP2 [DGVbeta]
DECIPHERUPP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUPP2 
Mutations
ICGC Data PortalUPP2 
TCGA Data PortalUPP2 
Broad Tumor PortalUPP2
OASIS PortalUPP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUPP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUPP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UPP2
DgiDB (Drug Gene Interaction Database)UPP2
DoCM (Curated mutations)UPP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UPP2 (select a term)
intoGenUPP2
Cancer3DUPP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617340   
Orphanet
MedgenUPP2
Genetic Testing Registry UPP2
NextProtO95045 [Medical]
TSGene151531
GENETestsUPP2
Target ValidationUPP2
Huge Navigator UPP2 [HugePedia]
snp3D : Map Gene to Disease151531
BioCentury BCIQUPP2
ClinGenUPP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151531
Chemical/Pharm GKB GenePA134866434
Clinical trialUPP2
Miscellaneous
canSAR (ICR)UPP2 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUPP2
EVEXUPP2
GoPubMedUPP2
iHOPUPP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:43:18 CEST 2017

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