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UROC1 (urocanate hydratase 1)

Identity

Alias_namesurocanase domain containing 1
Alias_symbol (synonym)FLJ31300
HMFN0320
Other aliasUROCD
HGNC (Hugo) UROC1
LocusID (NCBI) 131669
Atlas_Id 75515
Location 3q21.3  [Link to chromosome band 3q21]
Location_base_pair Starts at 126481165 and ends at 126517773 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SLC30A7 (1p21.2) / UROC1 (3q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UROC1   26444
Cards
Entrez_Gene (NCBI)UROC1  131669  urocanate hydratase 1
AliasesHMFN0320; UROCD
GeneCards (Weizmann)UROC1
Ensembl hg19 (Hinxton)ENSG00000159650 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159650 [Gene_View]  chr3:126481165-126517773 [Contig_View]  UROC1 [Vega]
ICGC DataPortalENSG00000159650
TCGA cBioPortalUROC1
AceView (NCBI)UROC1
Genatlas (Paris)UROC1
WikiGenes131669
SOURCE (Princeton)UROC1
Genetics Home Reference (NIH)UROC1
Genomic and cartography
GoldenPath hg38 (UCSC)UROC1  -     chr3:126481165-126517773 -  3q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UROC1  -     3q21.3   [Description]    (hg19-Feb_2009)
EnsemblUROC1 - 3q21.3 [CytoView hg19]  UROC1 - 3q21.3 [CytoView hg38]
Mapping of homologs : NCBIUROC1 [Mapview hg19]  UROC1 [Mapview hg38]
OMIM276880   613012   
Gene and transcription
Genbank (Entrez)AB075869 AK055862 BC115405 BC115406 BX108463
RefSeq transcript (Entrez)NM_001165974 NM_144639
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UROC1
Cluster EST : UnigeneHs.331148 [ NCBI ]
CGAP (NCI)Hs.331148
Alternative Splicing GalleryENSG00000159650
Gene ExpressionUROC1 [ NCBI-GEO ]   UROC1 [ EBI - ARRAY_EXPRESS ]   UROC1 [ SEEK ]   UROC1 [ MEM ]
Gene Expression Viewer (FireBrowse)UROC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131669
GTEX Portal (Tissue expression)UROC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96N76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96N76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96N76
Splice isoforms : SwissVarQ96N76
Catalytic activity : Enzyme4.2.1.49 [ Enzyme-Expasy ]   4.2.1.494.2.1.49 [ IntEnz-EBI ]   4.2.1.49 [ BRENDA ]   4.2.1.49 [ KEGG ]   
PhosPhoSitePlusQ96N76
Domaine pattern : Prosite (Expaxy)UROCANASE (PS01233)   
Domains : Interpro (EBI)Urocanase    Urocanase_CS   
Domain families : Pfam (Sanger)Urocanase (PF01175)   
Domain families : Pfam (NCBI)pfam01175   
Conserved Domain (NCBI)UROC1
DMDM Disease mutations131669
Blocks (Seattle)UROC1
SuperfamilyQ96N76
Human Protein AtlasENSG00000159650
Peptide AtlasQ96N76
HPRD08712
IPIIPI00043499   IPI00470790   
Protein Interaction databases
DIP (DOE-UCLA)Q96N76
IntAct (EBI)Q96N76
FunCoupENSG00000159650
BioGRIDUROC1
STRING (EMBL)UROC1
ZODIACUROC1
Ontologies - Pathways
QuickGOQ96N76
Ontology : AmiGOcytosol  cytosol  histidine catabolic process  histidine catabolic process  urocanate hydratase activity  urocanate hydratase activity  histidine catabolic process to glutamate and formamide  histidine catabolic process to glutamate and formate  
Ontology : EGO-EBIcytosol  cytosol  histidine catabolic process  histidine catabolic process  urocanate hydratase activity  urocanate hydratase activity  histidine catabolic process to glutamate and formamide  histidine catabolic process to glutamate and formate  
Pathways : KEGGHistidine metabolism   
NDEx NetworkUROC1
Atlas of Cancer Signalling NetworkUROC1
Wikipedia pathwaysUROC1
Orthology - Evolution
OrthoDB131669
GeneTree (enSembl)ENSG00000159650
Phylogenetic Trees/Animal Genes : TreeFamUROC1
HOVERGENQ96N76
HOGENOMQ96N76
Homologs : HomoloGeneUROC1
Homology/Alignments : Family Browser (UCSC)UROC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUROC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UROC1
dbVarUROC1
ClinVarUROC1
1000_GenomesUROC1 
Exome Variant ServerUROC1
ExAC (Exome Aggregation Consortium)UROC1 (select the gene name)
Genetic variants : HAPMAP131669
Genomic Variants (DGV)UROC1 [DGVbeta]
DECIPHERUROC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUROC1 
Mutations
ICGC Data PortalUROC1 
TCGA Data PortalUROC1 
Broad Tumor PortalUROC1
OASIS PortalUROC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUROC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUROC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UROC1
DgiDB (Drug Gene Interaction Database)UROC1
DoCM (Curated mutations)UROC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UROC1 (select a term)
intoGenUROC1
Cancer3DUROC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM276880    613012   
Orphanet18685   
MedgenUROC1
Genetic Testing Registry UROC1
NextProtQ96N76 [Medical]
TSGene131669
GENETestsUROC1
Target ValidationUROC1
Huge Navigator UROC1 [HugePedia]
snp3D : Map Gene to Disease131669
BioCentury BCIQUROC1
ClinGenUROC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD131669
Chemical/Pharm GKB GenePA134879207
Clinical trialUROC1
Miscellaneous
canSAR (ICR)UROC1 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUROC1
EVEXUROC1
GoPubMedUROC1
iHOPUROC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:43:20 CEST 2017

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