USF2 (upstream transcription factor 2, c-fos interacting)

2007-02-01  

Identity

HGNC
LOCATION
19q13.12
LOCUSID
ALIAS
FIP,bHLHb12
FUSION GENES

Other Information

Locus ID:

NCBI: 7392
MIM: 600390
HGNC: 12594
Ensembl: ENSG00000105698

Variants:

dbSNP: 7392
ClinVar: 7392
TCGA: ENSG00000105698
COSMIC: USF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105698ENST00000222305Q15853
ENSG00000105698ENST00000343550Q15853
ENSG00000105698ENST00000379134Q15853
ENSG00000105698ENST00000594064B4DLJ1
ENSG00000105698ENST00000595068Q15853
ENSG00000105698ENST00000596380M0R1C6
ENSG00000105698ENST00000597671M0QZ39
ENSG00000105698ENST00000598058M0QY46
ENSG00000105698ENST00000599471M0QXT0
ENSG00000105698ENST00000599625M0QYU7
ENSG00000105698ENST00000602164V9GYR5

Expression (GTEx)

0
50
100
150
200
250

References

Pubmed IDYearTitleCitations
190748282008Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth.79
197306832009The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.59
129707522003Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor.44
229662062012Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia.30
181654392008Upstream stimulatory factor-2 regulates steroidogenic factor-1 expression in endometriosis.24
157674392005TFII-I regulates induction of chromosomally integrated human immunodeficiency virus type 1 long terminal repeat in cooperation with USF.20
129173342003USF1 and USF2 mediate inhibition of human trophoblast differentiation and CYP19 gene expression by Mash-2 and hypoxia.19
190899092009HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells.16
239910992013STAT3 or USF2 contributes to HIF target gene specificity.15
152423502004Upstream stimulatory factors, USF1 and USF2, bind to the human haem oxygenase-1 proximal promoter in vivo and regulate its transcription.14

Citation

Dessen P

USF2 (upstream transcription factor 2, c-fos interacting)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46357/usf2