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USF2 (upstream transcription factor 2, c-fos interacting)

Identity

Alias_symbol (synonym)FIP
bHLHb12
Other alias
HGNC (Hugo) USF2
LocusID (NCBI) 7392
Atlas_Id 46357
Location 19q13.12  [Link to chromosome band 19q13]
Location_base_pair Starts at 35759896 and ends at 35770718 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDC5L (6p21.1) / USF2 (19q13.12)TNNI3 (19q13.42) / USF2 (19q13.12)USF2 (19q13.12) / CDC5L (6p21.1)
USF2 (19q13.12) / IRX3 (16q12.2)USF2 (19q13.12) / USF2 (19q13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USF2   12594
Cards
Entrez_Gene (NCBI)USF2  7392  upstream transcription factor 2, c-fos interacting
AliasesFIP; bHLHb12
GeneCards (Weizmann)USF2
Ensembl hg19 (Hinxton)ENSG00000105698 [Gene_View]  chr19:35759896-35770718 [Contig_View]  USF2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105698 [Gene_View]  chr19:35759896-35770718 [Contig_View]  USF2 [Vega]
ICGC DataPortalENSG00000105698
TCGA cBioPortalUSF2
AceView (NCBI)USF2
Genatlas (Paris)USF2
WikiGenes7392
SOURCE (Princeton)USF2
Genetics Home Reference (NIH)USF2
Genomic and cartography
GoldenPath hg19 (UCSC)USF2  -     chr19:35759896-35770718 +  19q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)USF2  -     19q13.12   [Description]    (hg38-Dec_2013)
EnsemblUSF2 - 19q13.12 [CytoView hg19]  USF2 - 19q13.12 [CytoView hg38]
Mapping of homologs : NCBIUSF2 [Mapview hg19]  USF2 [Mapview hg38]
OMIM600390   
Gene and transcription
Genbank (Entrez)AI240594 AK297022 AY147880 BC042655 BC049821
RefSeq transcript (Entrez)NM_001321150 NM_003367 NM_207291
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_029241 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)USF2
Cluster EST : UnigeneHs.454534 [ NCBI ]
CGAP (NCI)Hs.454534
Alternative Splicing GalleryENSG00000105698
Gene ExpressionUSF2 [ NCBI-GEO ]   USF2 [ EBI - ARRAY_EXPRESS ]   USF2 [ SEEK ]   USF2 [ MEM ]
Gene Expression Viewer (FireBrowse)USF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7392
GTEX Portal (Tissue expression)USF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15853   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15853  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15853
Splice isoforms : SwissVarQ15853
PhosPhoSitePlusQ15853
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)USF2
DMDM Disease mutations7392
Blocks (Seattle)USF2
SuperfamilyQ15853
Human Protein AtlasENSG00000105698
Peptide AtlasQ15853
HPRD02668
IPIIPI00020037   IPI00216376   IPI00216377   IPI00910387   IPI00432448   
Protein Interaction databases
DIP (DOE-UCLA)Q15853
IntAct (EBI)Q15853
FunCoupENSG00000105698
BioGRIDUSF2
STRING (EMBL)USF2
ZODIACUSF2
Ontologies - Pathways
QuickGOQ15853
Ontology : AmiGOregulation of transcription from RNA polymerase II promoter by glucose  positive regulation of transcription from RNA polymerase II promoter by glucose  positive regulation of transcription from RNA polymerase II promoter by glucose  transcription factor activity, sequence-specific DNA binding  transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding  protein binding  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  lactation  late viral transcription  protein homodimerization activity  intracellular membrane-bounded organelle  bHLH transcription factor binding  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  lipid homeostasis  
Ontology : EGO-EBIregulation of transcription from RNA polymerase II promoter by glucose  positive regulation of transcription from RNA polymerase II promoter by glucose  positive regulation of transcription from RNA polymerase II promoter by glucose  transcription factor activity, sequence-specific DNA binding  transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding  protein binding  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  lactation  late viral transcription  protein homodimerization activity  intracellular membrane-bounded organelle  bHLH transcription factor binding  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  lipid homeostasis  
NDEx NetworkUSF2
Atlas of Cancer Signalling NetworkUSF2
Wikipedia pathwaysUSF2
Orthology - Evolution
OrthoDB7392
GeneTree (enSembl)ENSG00000105698
Phylogenetic Trees/Animal Genes : TreeFamUSF2
HOVERGENQ15853
HOGENOMQ15853
Homologs : HomoloGeneUSF2
Homology/Alignments : Family Browser (UCSC)USF2
Gene fusions - Rearrangements
Fusion : MitelmanUSF2/IRX3 [19q13.12/16q12.2]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USF2
dbVarUSF2
ClinVarUSF2
1000_GenomesUSF2 
Exome Variant ServerUSF2
ExAC (Exome Aggregation Consortium)USF2 (select the gene name)
Genetic variants : HAPMAP7392
Genomic Variants (DGV)USF2 [DGVbeta]
DECIPHER (Syndromes)19:35759896-35770718  ENSG00000105698
CONAN: Copy Number AnalysisUSF2 
Mutations
ICGC Data PortalUSF2 
TCGA Data PortalUSF2 
Broad Tumor PortalUSF2
OASIS PortalUSF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USF2
DgiDB (Drug Gene Interaction Database)USF2
DoCM (Curated mutations)USF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USF2 (select a term)
intoGenUSF2
Cancer3DUSF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600390   
Orphanet
MedgenUSF2
Genetic Testing Registry USF2
NextProtQ15853 [Medical]
TSGene7392
GENETestsUSF2
Huge Navigator USF2 [HugePedia]
snp3D : Map Gene to Disease7392
BioCentury BCIQUSF2
ClinGenUSF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7392
Chemical/Pharm GKB GenePA37224
Clinical trialUSF2
Miscellaneous
canSAR (ICR)USF2 (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSF2
EVEXUSF2
GoPubMedUSF2
iHOPUSF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:33:32 CET 2017

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