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USP11 (ubiquitin specific peptidase 11)

Identity

Alias_namesubiquitin specific protease 11
Alias_symbol (synonym)UHX1
Other alias
HGNC (Hugo) USP11
LocusID (NCBI) 8237
Atlas_Id 45825
Location Xp11.3  [Link to chromosome band Xp11]
Location_base_pair Starts at 47232915 and ends at 47248328 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ASAP2 (2p25.1) / USP11 (Xp11.23)PRR14L (22q12.2) / USP11 (Xp11.23)USP11 (Xp11.23) / DYNC2H1 (11q22.3)
USP11 (Xp11.23) / PRODH (22q11.21)USP11 (Xp11.23) / SAV1 (14q22.1)USP11 (Xp11.23) / SIRPA (20p13)
USP11 (Xp11.23) / USP11 (Xp11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP11   12609
Cards
Entrez_Gene (NCBI)USP11  8237  ubiquitin specific peptidase 11
AliasesUHX1
GeneCards (Weizmann)USP11
Ensembl hg19 (Hinxton)ENSG00000102226 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102226 [Gene_View]  chrX:47232915-47248328 [Contig_View]  USP11 [Vega]
ICGC DataPortalENSG00000102226
TCGA cBioPortalUSP11
AceView (NCBI)USP11
Genatlas (Paris)USP11
WikiGenes8237
SOURCE (Princeton)USP11
Genetics Home Reference (NIH)USP11
Genomic and cartography
GoldenPath hg38 (UCSC)USP11  -     chrX:47232915-47248328 +  Xp11.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP11  -     Xp11.3   [Description]    (hg19-Feb_2009)
EnsemblUSP11 - Xp11.3 [CytoView hg19]  USP11 - Xp11.3 [CytoView hg38]
Mapping of homologs : NCBIUSP11 [Mapview hg19]  USP11 [Mapview hg38]
OMIM300050   
Gene and transcription
Genbank (Entrez)AB073597 AK055588 AK098394 AK294635 BC000350
RefSeq transcript (Entrez)NM_004651
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP11
Cluster EST : UnigeneHs.171501 [ NCBI ]
CGAP (NCI)Hs.171501
Alternative Splicing GalleryENSG00000102226
Gene ExpressionUSP11 [ NCBI-GEO ]   USP11 [ EBI - ARRAY_EXPRESS ]   USP11 [ SEEK ]   USP11 [ MEM ]
Gene Expression Viewer (FireBrowse)USP11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8237
GTEX Portal (Tissue expression)USP11
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51784   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51784  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51784
Splice isoforms : SwissVarP51784
PhosPhoSitePlusP51784
Domaine pattern : Prosite (Expaxy)DUSP (PS51283)    USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)Pept_C19_DUSP    Peptidase_C19_UCH    Ub_USP-typ    USP_C    USP_CS    USP_dom   
Domain families : Pfam (Sanger)DUSP (PF06337)    Ubiquitin_3 (PF14836)    UCH (PF00443)    USP7_C2 (PF14533)   
Domain families : Pfam (NCBI)pfam06337    pfam14836    pfam00443    pfam14533   
Domain families : Smart (EMBL)DUSP (SM00695)  
Conserved Domain (NCBI)USP11
DMDM Disease mutations8237
Blocks (Seattle)USP11
PDB (SRS)4MEL   
PDB (PDBSum)4MEL   
PDB (IMB)4MEL   
PDB (RSDB)4MEL   
Structural Biology KnowledgeBase4MEL   
SCOP (Structural Classification of Proteins)4MEL   
CATH (Classification of proteins structures)4MEL   
SuperfamilyP51784
Human Protein AtlasENSG00000102226
Peptide AtlasP51784
HPRD02081
IPIIPI00184533   IPI00646574   IPI01015533   
Protein Interaction databases
DIP (DOE-UCLA)P51784
IntAct (EBI)P51784
FunCoupENSG00000102226
BioGRIDUSP11
STRING (EMBL)USP11
ZODIACUSP11
Ontologies - Pathways
QuickGOP51784
Ontology : AmiGOcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  chromosome  cytosol  cytosol  ubiquitin-dependent protein catabolic process  protein deubiquitination  protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  
Ontology : EGO-EBIcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  chromosome  cytosol  cytosol  ubiquitin-dependent protein catabolic process  protein deubiquitination  protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  
NDEx NetworkUSP11
Atlas of Cancer Signalling NetworkUSP11
Wikipedia pathwaysUSP11
Orthology - Evolution
OrthoDB8237
GeneTree (enSembl)ENSG00000102226
Phylogenetic Trees/Animal Genes : TreeFamUSP11
HOVERGENP51784
HOGENOMP51784
Homologs : HomoloGeneUSP11
Homology/Alignments : Family Browser (UCSC)USP11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP11
dbVarUSP11
ClinVarUSP11
1000_GenomesUSP11 
Exome Variant ServerUSP11
ExAC (Exome Aggregation Consortium)USP11 (select the gene name)
Genetic variants : HAPMAP8237
Genomic Variants (DGV)USP11 [DGVbeta]
DECIPHERUSP11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP11 
Mutations
ICGC Data PortalUSP11 
TCGA Data PortalUSP11 
Broad Tumor PortalUSP11
OASIS PortalUSP11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch USP11
DgiDB (Drug Gene Interaction Database)USP11
DoCM (Curated mutations)USP11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP11 (select a term)
intoGenUSP11
Cancer3DUSP11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300050   
Orphanet
MedgenUSP11
Genetic Testing Registry USP11
NextProtP51784 [Medical]
TSGene8237
GENETestsUSP11
Target ValidationUSP11
Huge Navigator USP11 [HugePedia]
snp3D : Map Gene to Disease8237
BioCentury BCIQUSP11
ClinGenUSP11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8237
Chemical/Pharm GKB GenePA37235
Clinical trialUSP11
Miscellaneous
canSAR (ICR)USP11 (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP11
EVEXUSP11
GoPubMedUSP11
iHOPUSP11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:36 CEST 2017

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