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USP12 (ubiquitin specific peptidase 12)

Identity

Alias_namesUSP12L1
ubiquitin specific protease 12 like 1
ubiquitin specific protease 12
Other aliasUBH1
HGNC (Hugo) USP12
LocusID (NCBI) 219333
Atlas_Id 53833
Location 13q12.13  [Link to chromosome band 13q12]
Location_base_pair Starts at 27640287 and ends at 27746033 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
JPX (Xq13.2) / USP12 (13q12.13)USP12 (13q12.13) / E2F3 (6p22.3)USP12 (13q12.13) / POLR2A (17p13.1)
USP12 (13q12.13) / SRCAP (16p11.2)USP12 13q12.13 / E2F3 6p22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP12   20485
Cards
Entrez_Gene (NCBI)USP12  219333  ubiquitin specific peptidase 12
AliasesUBH1; USP12L1
GeneCards (Weizmann)USP12
Ensembl hg19 (Hinxton)ENSG00000152484 [Gene_View]  chr13:27640287-27746033 [Contig_View]  USP12 [Vega]
Ensembl hg38 (Hinxton)ENSG00000152484 [Gene_View]  chr13:27640287-27746033 [Contig_View]  USP12 [Vega]
ICGC DataPortalENSG00000152484
TCGA cBioPortalUSP12
AceView (NCBI)USP12
Genatlas (Paris)USP12
WikiGenes219333
SOURCE (Princeton)USP12
Genetics Home Reference (NIH)USP12
Genomic and cartography
GoldenPath hg19 (UCSC)USP12  -     chr13:27640287-27746033 -  13q12.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)USP12  -     13q12.13   [Description]    (hg38-Dec_2013)
EnsemblUSP12 - 13q12.13 [CytoView hg19]  USP12 - 13q12.13 [CytoView hg38]
Mapping of homologs : NCBIUSP12 [Mapview hg19]  USP12 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF022789 AK289685 AL049221 BC026072 DQ894074
RefSeq transcript (Entrez)NM_182488
RefSeq genomic (Entrez)NC_000013 NC_018924 NT_024524 NW_004929388
Consensus coding sequences : CCDS (NCBI)USP12
Cluster EST : UnigeneHs.42400 [ NCBI ]
CGAP (NCI)Hs.42400
Alternative Splicing GalleryENSG00000152484
Gene ExpressionUSP12 [ NCBI-GEO ]   USP12 [ EBI - ARRAY_EXPRESS ]   USP12 [ SEEK ]   USP12 [ MEM ]
Gene Expression Viewer (FireBrowse)USP12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)219333
GTEX Portal (Tissue expression)USP12
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75317   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75317  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75317
Splice isoforms : SwissVarO75317
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusO75317
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)Peptidase_C19_UCH    USP_CS    USP_dom   
Domain families : Pfam (Sanger)UCH (PF00443)   
Domain families : Pfam (NCBI)pfam00443   
Conserved Domain (NCBI)USP12
DMDM Disease mutations219333
Blocks (Seattle)USP12
SuperfamilyO75317
Human Protein AtlasENSG00000152484
Peptide AtlasO75317
HPRD15631
IPIIPI00290893   
Protein Interaction databases
DIP (DOE-UCLA)O75317
IntAct (EBI)O75317
FunCoupENSG00000152484
BioGRIDUSP12
STRING (EMBL)USP12
ZODIACUSP12
Ontologies - Pathways
QuickGOO75317
Ontology : AmiGOcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  protein binding  cellular_component  ubiquitin-dependent protein catabolic process  protein deubiquitination  
Ontology : EGO-EBIcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  protein binding  cellular_component  ubiquitin-dependent protein catabolic process  protein deubiquitination  
NDEx NetworkUSP12
Atlas of Cancer Signalling NetworkUSP12
Wikipedia pathwaysUSP12
Orthology - Evolution
OrthoDB219333
GeneTree (enSembl)ENSG00000152484
Phylogenetic Trees/Animal Genes : TreeFamUSP12
HOVERGENO75317
HOGENOMO75317
Homologs : HomoloGeneUSP12
Homology/Alignments : Family Browser (UCSC)USP12
Gene fusions - Rearrangements
Fusion : MitelmanUSP12/E2F3 [13q12.13/6p22.3]  
Fusion: TCGAUSP12 13q12.13 E2F3 6p22.3 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP12
dbVarUSP12
ClinVarUSP12
1000_GenomesUSP12 
Exome Variant ServerUSP12
ExAC (Exome Aggregation Consortium)USP12 (select the gene name)
Genetic variants : HAPMAP219333
Genomic Variants (DGV)USP12 [DGVbeta]
DECIPHER (Syndromes)13:27640287-27746033  ENSG00000152484
CONAN: Copy Number AnalysisUSP12 
Mutations
ICGC Data PortalUSP12 
TCGA Data PortalUSP12 
Broad Tumor PortalUSP12
OASIS PortalUSP12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP12
DgiDB (Drug Gene Interaction Database)USP12
DoCM (Curated mutations)USP12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP12 (select a term)
intoGenUSP12
Cancer3DUSP12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenUSP12
Genetic Testing Registry USP12
NextProtO75317 [Medical]
TSGene219333
GENETestsUSP12
Huge Navigator USP12 [HugePedia]
snp3D : Map Gene to Disease219333
BioCentury BCIQUSP12
ClinGenUSP12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD219333
Chemical/Pharm GKB GenePA37236
Clinical trialUSP12
Miscellaneous
canSAR (ICR)USP12 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP12
EVEXUSP12
GoPubMedUSP12
iHOPUSP12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:24:29 CEST 2017

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