USP14 (ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase))

Identity

Other names	TGT
HGNC	USP14
Location	18p11.32
Location_base_pair	Starts at 148483 and ends at 203739 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	USP14   12612
Entrez_Gene	USP14  9097  ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
	Cards
GeneCards	USP14
Ensembl	ENSG00000101557 [Gene_View]  USP14 [Vega]
Genatlas	USP14
	Genomic and cartography
GoldenPath	USP14  -  18p11.32   chr18:148483-203739 +  18p11.32   [Description]    (hg18-March_2006)
Ensembl	USP14 - 18p11.32 [CytoView]
NCBI	Mapview
OMIM	607274 Disease map [OMIM]
HomoloGene	USP14
	Gene and transcription
Genbank	AK095516 [ ENTREZ ]
Genbank	AK098497 [ ENTREZ ]
Genbank	AK315438 [ ENTREZ ]
Genbank	BC003556 [ ENTREZ ]
Genbank	BG717018 [ ENTREZ ]
RefSeq	NM_001037334 [ SRS ]    NM_001037334 [ ENTREZ ]
RefSeq	NM_005151 [ SRS ]    NM_005151 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010859 [ SRS ]    NT_010859 [ ENTREZ ]
RefSeq	NW_001838461 [ SRS ]    NW_001838461 [ ENTREZ ]
RefSeq	NW_926940 [ SRS ]    NW_926940 [ ENTREZ ]
CCDS	USP14 CCDS - NCBI
AceView	USP14 AceView - NCBI
Unigene	Hs.707058 [ SRS ]    Hs.707058 [ NCBI ]
Fast-db	405 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P54578 [ SRS]    P54578 [ EXPASY ]     P54578 [ INTERPRO ]     P54578 [ UNIPROT ] P54578 [ VarSplice FASTA ]
Prosite	PS00299 UBIQUITIN_1 [ SRS ]    PS00299 UBIQUITIN_1 [ Expasy ]
Prosite	PS50053 UBIQUITIN_2 [ SRS ]    PS50053 UBIQUITIN_2 [ Expasy ]
Prosite	PS00972 UCH_2_1 [ SRS ]    PS00972 UCH_2_1 [ Expasy ]
Prosite	PS00973 UCH_2_2 [ SRS ]    PS00973 UCH_2_2 [ Expasy ]
Prosite	PS50235 UCH_2_3 [ SRS ]    PS50235 UCH_2_3 [ Expasy ]
Interpro	IPR001394 Peptidase_C19 [ SRS ]    IPR001394 Peptidase_C19 [ EBI ]
Interpro	IPR000626 Ubiquitin [ SRS ]    IPR000626 Ubiquitin [ EBI ]
CluSTr	P54578
Pfam	PF00443 UCH [ SRS ]    PF00443 UCH [ Sanger ]    pfam00443 [ NCBI-CDD ]
Smart	SM00213 UBQ [EMBL]
Blocks	P54578
PDB	2AYN [ SRS ]    2AYN [ PdbSum ],   2AYN [ IMB ]   2AYN [ RSDB ]
PDB	2AYO [ SRS ]    2AYO [ PdbSum ],   2AYO [ IMB ]   2AYO [ RSDB ]
HPRD	06279
	Protein Interaction databases
DIP	P54578
IntAct	P54578
	Polymorphism : SNP, mutations, diseases
OMIM	607274    [ map ]
GENETests	607274
SNP	USP14 [dbSNP-NCBI]
SNP	NM_001037334 [SNP-NCI]
SNP	NM_005151 [SNP-NCI]
SNP	USP14 [GeneSNPs - Utah]  USP14] [HGBASE - SRS]
HAPMAP	USP14 [HAPMAP]
COSMIC	USP14 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	USP14
Genetic Association	USP14
CDC HuGE	USP14
	General knowledge
Family Browser	USP14 [UCSC Family Browser]
SOURCE	NM_001037334
SOURCE	NM_005151
SMD	Hs.707058
SAGE	Hs.707058
Enzyme	3.1.2.15 [ Enzyme-Expasy ]   3.1.2.15 [ Enzyme-SRS ]   3.1.2.15 [ IntEnz-EBI ]   3.1.2.15 [ BRENDA ]   3.1.2.15 [ KEGG ]
GO	cysteine-type endopeptidase activity [Amigo]  cysteine-type endopeptidase activity
GO	ubiquitin thiolesterase activity [Amigo]  ubiquitin thiolesterase activity
GO	protein modification process [Amigo]  protein modification process
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	tRNA guanylyltransferase activity [Amigo]  tRNA guanylyltransferase activity
PubGene	USP14
TreeFam	USP14
CTD	9097 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	USP14 Related clones (RZPD - Berlin)
	PubMed
PubMed	11 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:18:40 2008