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USP27X (ubiquitin specific peptidase 27, X-linked)

Identity

Other aliasMRX105
USP22L
USP27
HGNC (Hugo) USP27X
LocusID (NCBI) 389856
Atlas_Id 57107
Location Xp11.23  [Link to chromosome band Xp11]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP27X   13486
Cards
Entrez_Gene (NCBI)USP27X  389856  ubiquitin specific peptidase 27, X-linked
AliasesMRX105; USP22L; USP27
GeneCards (Weizmann)USP27X
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  - [Contig_View]  USP27X [Vega]
TCGA cBioPortalUSP27X
AceView (NCBI)USP27X
Genatlas (Paris)USP27X
WikiGenes389856
SOURCE (Princeton)USP27X
Genetics Home Reference (NIH)USP27X
Genomic and cartography
GoldenPath hg38 (UCSC)USP27X  -  
GoldenPath hg19 (UCSC)USP27X  -  
EnsemblUSP27X - [CytoView hg19]  USP27X - [CytoView hg38]
Mapping of homologs : NCBIUSP27X [Mapview hg19]  USP27X [Mapview hg38]
OMIM300975   300984   
Gene and transcription
Genbank (Entrez)AW290976 AY672104
RefSeq transcript (Entrez)NM_001145073
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP27X
Cluster EST : UnigeneHs.143587 [ NCBI ]
CGAP (NCI)Hs.143587
Gene ExpressionUSP27X [ NCBI-GEO ]   USP27X [ EBI - ARRAY_EXPRESS ]   USP27X [ SEEK ]   USP27X [ MEM ]
Gene Expression Viewer (FireBrowse)USP27X [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389856
GTEX Portal (Tissue expression)USP27X
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NNY8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NNY8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NNY8
Splice isoforms : SwissVarA6NNY8
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusA6NNY8
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)Peptidase_C19_UCH    USP_CS    USP_dom   
Domain families : Pfam (Sanger)UCH (PF00443)   
Domain families : Pfam (NCBI)pfam00443   
Conserved Domain (NCBI)USP27X
DMDM Disease mutations389856
Blocks (Seattle)USP27X
SuperfamilyA6NNY8
Peptide AtlasA6NNY8
IPIIPI00399220   
Protein Interaction databases
DIP (DOE-UCLA)A6NNY8
IntAct (EBI)A6NNY8
BioGRIDUSP27X
STRING (EMBL)USP27X
ZODIACUSP27X
Ontologies - Pathways
QuickGOA6NNY8
Ontology : AmiGOthiol-dependent ubiquitin-specific protease activity  nucleus  cytosol  ubiquitin-dependent protein catabolic process  protein deubiquitination  positive regulation of apoptotic process  protein stabilization  Lys63-specific deubiquitinase activity  protein K63-linked deubiquitination  protein K48-linked deubiquitination  Lys48-specific deubiquitinase activity  
Ontology : EGO-EBIthiol-dependent ubiquitin-specific protease activity  nucleus  cytosol  ubiquitin-dependent protein catabolic process  protein deubiquitination  positive regulation of apoptotic process  protein stabilization  Lys63-specific deubiquitinase activity  protein K63-linked deubiquitination  protein K48-linked deubiquitination  Lys48-specific deubiquitinase activity  
NDEx NetworkUSP27X
Atlas of Cancer Signalling NetworkUSP27X
Wikipedia pathwaysUSP27X
Orthology - Evolution
OrthoDB389856
Phylogenetic Trees/Animal Genes : TreeFamUSP27X
HOVERGENA6NNY8
HOGENOMA6NNY8
Homologs : HomoloGeneUSP27X
Homology/Alignments : Family Browser (UCSC)USP27X
Gene fusions - Rearrangements
Tumor Fusion PortalUSP27X
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP27X [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP27X
dbVarUSP27X
ClinVarUSP27X
1000_GenomesUSP27X 
Exome Variant ServerUSP27X
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP389856
Genomic Variants (DGV)USP27X [DGVbeta]
DECIPHERUSP27X [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP27X 
Mutations
ICGC Data PortalUSP27X 
TCGA Data PortalUSP27X 
Broad Tumor PortalUSP27X
OASIS PortalUSP27X [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP27X  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP27X
BioMutasearch USP27X
DgiDB (Drug Gene Interaction Database)USP27X
DoCM (Curated mutations)USP27X (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP27X (select a term)
intoGenUSP27X
Cancer3DUSP27X(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300975    300984   
Orphanet
DisGeNETUSP27X
MedgenUSP27X
Genetic Testing Registry USP27X
NextProtA6NNY8 [Medical]
TSGene389856
GENETestsUSP27X
Target ValidationUSP27X
Huge Navigator USP27X [HugePedia]
snp3D : Map Gene to Disease389856
BioCentury BCIQUSP27X
ClinGenUSP27X
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD389856
Chemical/Pharm GKB GenePA134993614
Clinical trialUSP27X
Miscellaneous
canSAR (ICR)USP27X (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP27X
EVEXUSP27X
GoPubMedUSP27X
iHOPUSP27X
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:41:02 CET 2017

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