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USP33 (ubiquitin specific peptidase 33)

Identity

Alias_namesubiquitin specific protease 33
Alias_symbol (synonym)KIAA1097
VDU1
Other alias
HGNC (Hugo) USP33
LocusID (NCBI) 23032
Atlas_Id 51144
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 77695989 and ends at 77759879 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RAPGEF6 (5q31.1) / USP33 (1p31.1)USP33 (1p31.1) / USP33 (1p31.1)ZFYVE9 (1p32.3) / USP33 (1p31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP33   20059
Cards
Entrez_Gene (NCBI)USP33  23032  ubiquitin specific peptidase 33
AliasesVDU1
GeneCards (Weizmann)USP33
Ensembl hg19 (Hinxton)ENSG00000077254 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000077254 [Gene_View]  chr1:77695989-77759879 [Contig_View]  USP33 [Vega]
ICGC DataPortalENSG00000077254
TCGA cBioPortalUSP33
AceView (NCBI)USP33
Genatlas (Paris)USP33
WikiGenes23032
SOURCE (Princeton)USP33
Genetics Home Reference (NIH)USP33
Genomic and cartography
GoldenPath hg38 (UCSC)USP33  -     chr1:77695989-77759879 -  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP33  -     1p31.1   [Description]    (hg19-Feb_2009)
EnsemblUSP33 - 1p31.1 [CytoView hg19]  USP33 - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBIUSP33 [Mapview hg19]  USP33 [Mapview hg38]
OMIM615146   
Gene and transcription
Genbank (Entrez)AB029020 AF383172 AF383173 AI569971 AK022864
RefSeq transcript (Entrez)NM_015017 NM_201624 NM_201626
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP33
Cluster EST : UnigeneHs.480597 [ NCBI ]
CGAP (NCI)Hs.480597
Alternative Splicing GalleryENSG00000077254
Gene ExpressionUSP33 [ NCBI-GEO ]   USP33 [ EBI - ARRAY_EXPRESS ]   USP33 [ SEEK ]   USP33 [ MEM ]
Gene Expression Viewer (FireBrowse)USP33 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23032
GTEX Portal (Tissue expression)USP33
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TEY7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TEY7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TEY7
Splice isoforms : SwissVarQ8TEY7
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusQ8TEY7
Domaine pattern : Prosite (Expaxy)DUSP (PS51283)    USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)    ZF_UBP (PS50271)   
Domains : Interpro (EBI)Pept_C19_DUSP    Peptidase_C19_UCH    USP_CS    USP_dom    Znf_RING/FYVE/PHD    Znf_UBP   
Domain families : Pfam (Sanger)DUSP (PF06337)    UCH (PF00443)    zf-UBP (PF02148)   
Domain families : Pfam (NCBI)pfam06337    pfam00443    pfam02148   
Domain families : Smart (EMBL)DUSP (SM00695)  ZnF_UBP (SM00290)  
Conserved Domain (NCBI)USP33
DMDM Disease mutations23032
Blocks (Seattle)USP33
PDB (SRS)2UZG   
PDB (PDBSum)2UZG   
PDB (IMB)2UZG   
PDB (RSDB)2UZG   
Structural Biology KnowledgeBase2UZG   
SCOP (Structural Classification of Proteins)2UZG   
CATH (Classification of proteins structures)2UZG   
SuperfamilyQ8TEY7
Human Protein AtlasENSG00000077254
Peptide AtlasQ8TEY7
HPRD10297
IPIIPI00236901   IPI00377264   IPI00402757   IPI00977588   IPI00976933   IPI00975608   IPI00980324   IPI00976300   IPI00980731   
Protein Interaction databases
DIP (DOE-UCLA)Q8TEY7
IntAct (EBI)Q8TEY7
FunCoupENSG00000077254
BioGRIDUSP33
STRING (EMBL)USP33
ZODIACUSP33
Ontologies - Pathways
QuickGOQ8TEY7
Ontology : AmiGOG-protein coupled receptor binding  cysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleoplasm  cytoplasm  autophagosome  Golgi apparatus  centrosome  cytosol  focal adhesion  ubiquitin-dependent protein catabolic process  endocytosis  axon guidance  zinc ion binding  regulation of G-protein coupled receptor protein signaling pathway  cellular response to starvation  regulation of autophagy  cell migration  protein deubiquitination  protein deubiquitination  protein deubiquitination  Ral GTPase binding  VCB complex  negative regulation of protein binding  positive regulation of protein binding  thiol-dependent ubiquitinyl hydrolase activity  ubiquitin binding  cell body  perinuclear region of cytoplasm  protein stabilization  centrosome duplication  protein K63-linked deubiquitination  protein K48-linked deubiquitination  
Ontology : EGO-EBIG-protein coupled receptor binding  cysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleoplasm  cytoplasm  autophagosome  Golgi apparatus  centrosome  cytosol  focal adhesion  ubiquitin-dependent protein catabolic process  endocytosis  axon guidance  zinc ion binding  regulation of G-protein coupled receptor protein signaling pathway  cellular response to starvation  regulation of autophagy  cell migration  protein deubiquitination  protein deubiquitination  protein deubiquitination  Ral GTPase binding  VCB complex  negative regulation of protein binding  positive regulation of protein binding  thiol-dependent ubiquitinyl hydrolase activity  ubiquitin binding  cell body  perinuclear region of cytoplasm  protein stabilization  centrosome duplication  protein K63-linked deubiquitination  protein K48-linked deubiquitination  
NDEx NetworkUSP33
Atlas of Cancer Signalling NetworkUSP33
Wikipedia pathwaysUSP33
Orthology - Evolution
OrthoDB23032
GeneTree (enSembl)ENSG00000077254
Phylogenetic Trees/Animal Genes : TreeFamUSP33
HOVERGENQ8TEY7
HOGENOMQ8TEY7
Homologs : HomoloGeneUSP33
Homology/Alignments : Family Browser (UCSC)USP33
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP33
dbVarUSP33
ClinVarUSP33
1000_GenomesUSP33 
Exome Variant ServerUSP33
ExAC (Exome Aggregation Consortium)USP33 (select the gene name)
Genetic variants : HAPMAP23032
Genomic Variants (DGV)USP33 [DGVbeta]
DECIPHERUSP33 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP33 
Mutations
ICGC Data PortalUSP33 
TCGA Data PortalUSP33 
Broad Tumor PortalUSP33
OASIS PortalUSP33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP33  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP33
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP33
DgiDB (Drug Gene Interaction Database)USP33
DoCM (Curated mutations)USP33 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP33 (select a term)
intoGenUSP33
Cancer3DUSP33(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615146   
Orphanet
MedgenUSP33
Genetic Testing Registry USP33
NextProtQ8TEY7 [Medical]
TSGene23032
GENETestsUSP33
Target ValidationUSP33
Huge Navigator USP33 [HugePedia]
snp3D : Map Gene to Disease23032
BioCentury BCIQUSP33
ClinGenUSP33
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23032
Chemical/Pharm GKB GenePA134955343
Clinical trialUSP33
Miscellaneous
canSAR (ICR)USP33 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP33
EVEXUSP33
GoPubMedUSP33
iHOPUSP33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:41 CEST 2017

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