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USP34 (ubiquitin specific peptidase 34)

Identity

Alias_namesubiquitin specific protease 34
Alias_symbol (synonym)KIAA0570
KIAA0729
Other alias-
HGNC (Hugo) USP34
LocusID (NCBI) 9736
Atlas_Id 75557
Location 2p15  [Link to chromosome band 2p15]
Location_base_pair Starts at 61187455 and ends at 61470714 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BAG1 (9p13.3) / USP34 (2p15)C3 (19p13.3) / USP34 (2p15)GALNT13 (2q23.3) / USP34 (2p15)
HBA2 (16p13.3) / USP34 (2p15)HINT1 (5q23.3) / USP34 (2p15)UBAP2 (9p13.3) / USP34 (2p15)
USP34 (2p15) / BCAT2 (19q13.33)USP34 (2p15) / CARKD (13q34)USP34 (2p15) / CCT4 (2p15)
USP34 (2p15) / FAM161A (2p15)USP34 (2p15) / HERPUD1 (16q13)USP34 (2p15) / HSDL2 (9q32)
USP34 (2p15) / RFC4 (3q27.3)USP34 (2p15) / TUBGCP3 (13q34)USP34 (2p15) / USP34 (2p15)
USP34 (2p15) / WDR92 (2p14)USP34 (2p15) / ZNF638 (2p13.2)USP34 FAM161A
USP34 WDR92

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP34   20066
Cards
Entrez_Gene (NCBI)USP34  9736  ubiquitin specific peptidase 34
Aliases
GeneCards (Weizmann)USP34
Ensembl hg19 (Hinxton)ENSG00000115464 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115464 [Gene_View]  chr2:61187455-61470714 [Contig_View]  USP34 [Vega]
ICGC DataPortalENSG00000115464
TCGA cBioPortalUSP34
AceView (NCBI)USP34
Genatlas (Paris)USP34
WikiGenes9736
SOURCE (Princeton)USP34
Genetics Home Reference (NIH)USP34
Genomic and cartography
GoldenPath hg38 (UCSC)USP34  -     chr2:61187455-61470714 -  2p15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP34  -     2p15   [Description]    (hg19-Feb_2009)
EnsemblUSP34 - 2p15 [CytoView hg19]  USP34 - 2p15 [CytoView hg38]
Mapping of homologs : NCBIUSP34 [Mapview hg19]  USP34 [Mapview hg38]
OMIM615295   
Gene and transcription
Genbank (Entrez)AB011142 AB018272 AJ586138 AK001193 AK022637
RefSeq transcript (Entrez)NM_014709
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP34
Cluster EST : UnigeneHs.644708 [ NCBI ]
CGAP (NCI)Hs.644708
Alternative Splicing GalleryENSG00000115464
Gene ExpressionUSP34 [ NCBI-GEO ]   USP34 [ EBI - ARRAY_EXPRESS ]   USP34 [ SEEK ]   USP34 [ MEM ]
Gene Expression Viewer (FireBrowse)USP34 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9736
GTEX Portal (Tissue expression)USP34
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ70CQ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ70CQ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ70CQ2
Splice isoforms : SwissVarQ70CQ2
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusQ70CQ2
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)ARM-type_fold    Peptidase_C19_UCH    USP_CS    USP_dom   
Domain families : Pfam (Sanger)UCH (PF00443)   
Domain families : Pfam (NCBI)pfam00443   
Conserved Domain (NCBI)USP34
DMDM Disease mutations9736
Blocks (Seattle)USP34
SuperfamilyQ70CQ2
Human Protein AtlasENSG00000115464
Peptide AtlasQ70CQ2
HPRD11665
IPIIPI00297593   IPI00787401   IPI00894492   IPI00914601   IPI00982046   IPI00941592   IPI00927157   
Protein Interaction databases
DIP (DOE-UCLA)Q70CQ2
IntAct (EBI)Q70CQ2
FunCoupENSG00000115464
BioGRIDUSP34
STRING (EMBL)USP34
ZODIACUSP34
Ontologies - Pathways
QuickGOQ70CQ2
Ontology : AmiGOcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  protein binding  cytosol  ubiquitin-dependent protein catabolic process  Wnt signaling pathway  protein deubiquitination  protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  protein K48-linked deubiquitination  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  protein binding  cytosol  ubiquitin-dependent protein catabolic process  Wnt signaling pathway  protein deubiquitination  protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  protein K48-linked deubiquitination  positive regulation of canonical Wnt signaling pathway  
NDEx NetworkUSP34
Atlas of Cancer Signalling NetworkUSP34
Wikipedia pathwaysUSP34
Orthology - Evolution
OrthoDB9736
GeneTree (enSembl)ENSG00000115464
Phylogenetic Trees/Animal Genes : TreeFamUSP34
HOVERGENQ70CQ2
HOGENOMQ70CQ2
Homologs : HomoloGeneUSP34
Homology/Alignments : Family Browser (UCSC)USP34
Gene fusions - Rearrangements
Fusion: TCGAUSP34 FAM161A
Fusion: TCGAUSP34 WDR92
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP34 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP34
dbVarUSP34
ClinVarUSP34
1000_GenomesUSP34 
Exome Variant ServerUSP34
ExAC (Exome Aggregation Consortium)USP34 (select the gene name)
Genetic variants : HAPMAP9736
Genomic Variants (DGV)USP34 [DGVbeta]
DECIPHERUSP34 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP34 
Mutations
ICGC Data PortalUSP34 
TCGA Data PortalUSP34 
Broad Tumor PortalUSP34
OASIS PortalUSP34 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP34  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP34
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP34
DgiDB (Drug Gene Interaction Database)USP34
DoCM (Curated mutations)USP34 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP34 (select a term)
intoGenUSP34
Cancer3DUSP34(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615295   
Orphanet
MedgenUSP34
Genetic Testing Registry USP34
NextProtQ70CQ2 [Medical]
TSGene9736
GENETestsUSP34
Target ValidationUSP34
Huge Navigator USP34 [HugePedia]
snp3D : Map Gene to Disease9736
BioCentury BCIQUSP34
ClinGenUSP34
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9736
Chemical/Pharm GKB GenePA134897042
Clinical trialUSP34
Miscellaneous
canSAR (ICR)USP34 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP34
EVEXUSP34
GoPubMedUSP34
iHOPUSP34
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:48:26 CEST 2017

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