USP36 (ubiquitin specific peptidase 36)

2008-09-01 Affiliation

Identity

HGNC

USP36

LOCATION

17q25.3

LOCUSID

57602

ALIAS

DUB1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 57602
MIM: 612543
HGNC: 20062
Ensembl: ENSG00000055483

Variants:

dbSNP: 57602
ClinVar: 57602
TCGA: ENSG00000055483
COSMIC: USP36

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000055483	ENST00000312010	Q9P275
ENSG00000055483	ENST00000312010	A0A024R8V6
ENSG00000055483	ENST00000449938	E9PEW0
ENSG00000055483	ENST00000542802	Q9P275
ENSG00000055483	ENST00000542802	A0A024R8V6
ENSG00000055483	ENST00000586066	K7EMM6
ENSG00000055483	ENST00000586531	K7EPT1
ENSG00000055483	ENST00000586896	K7EQS0
ENSG00000055483	ENST00000587010	K7EKL7
ENSG00000055483	ENST00000587379	K7EIT7
ENSG00000055483	ENST00000587783	K7ERC1
ENSG00000055483	ENST00000588086	A0A075B784
ENSG00000055483	ENST00000588130	K7EIH0
ENSG00000055483	ENST00000588365	K7EJI3
ENSG00000055483	ENST00000589225	Q9P275
ENSG00000055483	ENST00000589225	A0A024R8V6
ENSG00000055483	ENST00000589424	K7ELR5
ENSG00000055483	ENST00000590546	Q8IXW9
ENSG00000055483	ENST00000591052	K7ERP8
ENSG00000055483	ENST00000591942	U3KQ92
ENSG00000055483	ENST00000592231	K7EKN3
ENSG00000055483	ENST00000592275	K7ELT3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
25775507	2015	The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc.	39
22622177	2012	The deubiquitinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins.	24
19208757	2009	Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36.	23
22865700	2012	Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitus.	16
19679658	2009	Nucleophosmin/B23 regulates ubiquitin dynamics in nucleoli by recruiting deubiquitylating enzyme USP36.	15
23773437	2013	Molecular mechanisms and functions of cytokine-inducible deubiquitinating enzymes.	13
18566677	2008	Differential display identifies overexpression of the USP36 gene, encoding a deubiquitinating enzyme, in ovarian cancer.	9
21268071	2011	Protein stability of mitochondrial superoxide dismutase SOD2 is regulated by USP36.	9
15809067	2005	Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated.	7
31550441	2019	Ubiquitin-specific protease USP36 knockdown impairs Parkin-dependent mitophagy via downregulation of Beclin-1-associated autophagy-related ATG14L.	4

Citation

Dessen P

USP36 (ubiquitin specific peptidase 36)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50353/usp36