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USP40 (ubiquitin specific peptidase 40)

Identity

Alias_namesubiquitin specific protease 40
Alias_symbol (synonym)FLJ10785
Other alias-
HGNC (Hugo) USP40
LocusID (NCBI) 55230
Atlas_Id 75561
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 234384165 and ends at 234474236 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARMC8 (3q22.3) / USP40 (2q37.1)UBE4B (1p36.22) / USP40 (2q37.1)USP40 (2q37.1) / ARMC8 (3q22.3)
USP40 (2q37.1) / E2F5 (8q21.2)USP40 (2q37.1) / PPIH (1p34.2)USP40 (2q37.1) / TUBG2 (17q21.2)
USP40 (2q37.1) / USP40 (2q37.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP40   20069
Cards
Entrez_Gene (NCBI)USP40  55230  ubiquitin specific peptidase 40
Aliases
GeneCards (Weizmann)USP40
Ensembl hg19 (Hinxton)ENSG00000085982 [Gene_View]  chr2:234384165-234474236 [Contig_View]  USP40 [Vega]
Ensembl hg38 (Hinxton)ENSG00000085982 [Gene_View]  chr2:234384165-234474236 [Contig_View]  USP40 [Vega]
ICGC DataPortalENSG00000085982
TCGA cBioPortalUSP40
AceView (NCBI)USP40
Genatlas (Paris)USP40
WikiGenes55230
SOURCE (Princeton)USP40
Genetics Home Reference (NIH)USP40
Genomic and cartography
GoldenPath hg19 (UCSC)USP40  -     chr2:234384165-234474236 -  2q37.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)USP40  -     2q37.1   [Description]    (hg38-Dec_2013)
EnsemblUSP40 - 2q37.1 [CytoView hg19]  USP40 - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBIUSP40 [Mapview hg19]  USP40 [Mapview hg38]
OMIM610570   
Gene and transcription
Genbank (Entrez)AI375976 AJ583821 AK001647 AK124094 AK295112
RefSeq transcript (Entrez)NM_018218
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929306
Consensus coding sequences : CCDS (NCBI)USP40
Cluster EST : UnigeneHs.96513 [ NCBI ]
CGAP (NCI)Hs.96513
Alternative Splicing GalleryENSG00000085982
Gene ExpressionUSP40 [ NCBI-GEO ]   USP40 [ EBI - ARRAY_EXPRESS ]   USP40 [ SEEK ]   USP40 [ MEM ]
Gene Expression Viewer (FireBrowse)USP40 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55230
GTEX Portal (Tissue expression)USP40
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NVE5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NVE5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NVE5
Splice isoforms : SwissVarQ9NVE5
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusQ9NVE5
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)Peptidase_C19_UCH    USP_CS    USP_dom   
Domain families : Pfam (Sanger)UCH (PF00443)   
Domain families : Pfam (NCBI)pfam00443   
Conserved Domain (NCBI)USP40
DMDM Disease mutations55230
Blocks (Seattle)USP40
SuperfamilyQ9NVE5
Human Protein AtlasENSG00000085982
Peptide AtlasQ9NVE5
HPRD07166
IPIIPI00947085   IPI00373874   IPI00398007   IPI00908421   IPI00917245   IPI00917413   IPI00916382   IPI00915798   
Protein Interaction databases
DIP (DOE-UCLA)Q9NVE5
IntAct (EBI)Q9NVE5
FunCoupENSG00000085982
BioGRIDUSP40
STRING (EMBL)USP40
ZODIACUSP40
Ontologies - Pathways
QuickGOQ9NVE5
Ontology : AmiGOcysteine-type endopeptidase activity  ubiquitin-specific protease activity  nucleus  cytoplasm  protein deubiquitination  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of proteasomal protein catabolic process  
Ontology : EGO-EBIcysteine-type endopeptidase activity  ubiquitin-specific protease activity  nucleus  cytoplasm  protein deubiquitination  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of proteasomal protein catabolic process  
NDEx NetworkUSP40
Atlas of Cancer Signalling NetworkUSP40
Wikipedia pathwaysUSP40
Orthology - Evolution
OrthoDB55230
GeneTree (enSembl)ENSG00000085982
Phylogenetic Trees/Animal Genes : TreeFamUSP40
HOVERGENQ9NVE5
HOGENOMQ9NVE5
Homologs : HomoloGeneUSP40
Homology/Alignments : Family Browser (UCSC)USP40
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP40 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP40
dbVarUSP40
ClinVarUSP40
1000_GenomesUSP40 
Exome Variant ServerUSP40
ExAC (Exome Aggregation Consortium)USP40 (select the gene name)
Genetic variants : HAPMAP55230
Genomic Variants (DGV)USP40 [DGVbeta]
DECIPHER (Syndromes)2:234384165-234474236  ENSG00000085982
CONAN: Copy Number AnalysisUSP40 
Mutations
ICGC Data PortalUSP40 
TCGA Data PortalUSP40 
Broad Tumor PortalUSP40
OASIS PortalUSP40 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP40  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP40
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP40
DgiDB (Drug Gene Interaction Database)USP40
DoCM (Curated mutations)USP40 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP40 (select a term)
intoGenUSP40
Cancer3DUSP40(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610570   
Orphanet
MedgenUSP40
Genetic Testing Registry USP40
NextProtQ9NVE5 [Medical]
TSGene55230
GENETestsUSP40
Huge Navigator USP40 [HugePedia]
snp3D : Map Gene to Disease55230
BioCentury BCIQUSP40
ClinGenUSP40
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55230
Chemical/Pharm GKB GenePA134909324
Clinical trialUSP40
Miscellaneous
canSAR (ICR)USP40 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP40
EVEXUSP40
GoPubMedUSP40
iHOPUSP40
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:51:05 CET 2017

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