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USP43 (ubiquitin specific peptidase 43)

Identity

Alias_namesubiquitin specific protease 43
Alias_symbol (synonym)FLJ30626
Other alias-
HGNC (Hugo) USP43
LocusID (NCBI) 124739
Atlas_Id 54762
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 9645537 and ends at 9729686 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RAB6A (11q13.4) / USP43 (17p13.1)USP43 (17p13.1) / CNTLN (9p22.2)USP43 (17p13.1) / ENDOV (17q25.3)
USP43 17p13.1 / ENDOV 17q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP43   20072
Cards
Entrez_Gene (NCBI)USP43  124739  ubiquitin specific peptidase 43
Aliases
GeneCards (Weizmann)USP43
Ensembl hg19 (Hinxton)ENSG00000154914 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154914 [Gene_View]  chr17:9645537-9729686 [Contig_View]  USP43 [Vega]
ICGC DataPortalENSG00000154914
TCGA cBioPortalUSP43
AceView (NCBI)USP43
Genatlas (Paris)USP43
WikiGenes124739
SOURCE (Princeton)USP43
Genetics Home Reference (NIH)USP43
Genomic and cartography
GoldenPath hg38 (UCSC)USP43  -     chr17:9645537-9729686 +  17p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP43  -     17p13.1   [Description]    (hg19-Feb_2009)
EnsemblUSP43 - 17p13.1 [CytoView hg19]  USP43 - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBIUSP43 [Mapview hg19]  USP43 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AJ583817 AK055188 AK090821 BC039653 BC136368
RefSeq transcript (Entrez)NM_001267576 NM_153210
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP43
Cluster EST : UnigeneHs.709621 [ NCBI ]
CGAP (NCI)Hs.709621
Alternative Splicing GalleryENSG00000154914
Gene ExpressionUSP43 [ NCBI-GEO ]   USP43 [ EBI - ARRAY_EXPRESS ]   USP43 [ SEEK ]   USP43 [ MEM ]
Gene Expression Viewer (FireBrowse)USP43 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)124739
GTEX Portal (Tissue expression)USP43
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ70EL4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ70EL4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ70EL4
Splice isoforms : SwissVarQ70EL4
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusQ70EL4
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)Peptidase_C19_UCH    USP_CS    USP_dom   
Domain families : Pfam (Sanger)UCH (PF00443)   
Domain families : Pfam (NCBI)pfam00443   
Conserved Domain (NCBI)USP43
DMDM Disease mutations124739
Blocks (Seattle)USP43
SuperfamilyQ70EL4
Human Protein AtlasENSG00000154914
Peptide AtlasQ70EL4
IPIIPI00739286   IPI00176488   IPI00166377   
Protein Interaction databases
DIP (DOE-UCLA)Q70EL4
IntAct (EBI)Q70EL4
FunCoupENSG00000154914
BioGRIDUSP43
STRING (EMBL)USP43
ZODIACUSP43
Ontologies - Pathways
QuickGOQ70EL4
Ontology : AmiGOnucleus  nucleoplasm  ubiquitin-dependent protein catabolic process  protein deubiquitination  ISG15-specific protease activity  translesion synthesis  thiol-dependent ubiquitinyl hydrolase activity  
Ontology : EGO-EBInucleus  nucleoplasm  ubiquitin-dependent protein catabolic process  protein deubiquitination  ISG15-specific protease activity  translesion synthesis  thiol-dependent ubiquitinyl hydrolase activity  
NDEx NetworkUSP43
Atlas of Cancer Signalling NetworkUSP43
Wikipedia pathwaysUSP43
Orthology - Evolution
OrthoDB124739
GeneTree (enSembl)ENSG00000154914
Phylogenetic Trees/Animal Genes : TreeFamUSP43
HOVERGENQ70EL4
HOGENOMQ70EL4
Homologs : HomoloGeneUSP43
Homology/Alignments : Family Browser (UCSC)USP43
Gene fusions - Rearrangements
Fusion : MitelmanRAB6A/USP43 [11q13.4/17p13.1]  [t(11;17)(q13;p13)]  
Fusion : MitelmanUSP43/ENDOV [17p13.1/17q25.3]  [t(17;17)(p13;q25)]  
Fusion: TCGAUSP43 17p13.1 ENDOV 17q25.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP43 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP43
dbVarUSP43
ClinVarUSP43
1000_GenomesUSP43 
Exome Variant ServerUSP43
ExAC (Exome Aggregation Consortium)USP43 (select the gene name)
Genetic variants : HAPMAP124739
Genomic Variants (DGV)USP43 [DGVbeta]
DECIPHERUSP43 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP43 
Mutations
ICGC Data PortalUSP43 
TCGA Data PortalUSP43 
Broad Tumor PortalUSP43
OASIS PortalUSP43 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP43  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP43
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP43
DgiDB (Drug Gene Interaction Database)USP43
DoCM (Curated mutations)USP43 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP43 (select a term)
intoGenUSP43
Cancer3DUSP43(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenUSP43
Genetic Testing Registry USP43
NextProtQ70EL4 [Medical]
TSGene124739
GENETestsUSP43
Target ValidationUSP43
Huge Navigator USP43 [HugePedia]
snp3D : Map Gene to Disease124739
BioCentury BCIQUSP43
ClinGenUSP43
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD124739
Chemical/Pharm GKB GenePA134865304
Clinical trialUSP43
Miscellaneous
canSAR (ICR)USP43 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP43
EVEXUSP43
GoPubMedUSP43
iHOPUSP43
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:42 CEST 2017

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