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USP44 (ubiquitin specific peptidase 44)

Identity

Alias_namesubiquitin specific protease 44
Alias_symbol (synonym)FLJ14528
Other alias-
HGNC (Hugo) USP44
LocusID (NCBI) 84101
Atlas_Id 52539
Location 12q22  [Link to chromosome band 12q22]
Location_base_pair Starts at 95516560 and ends at 95548844 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PRRC2A (6p21.33) / USP44 (12q22)USP44 (12q22) / P3H1 (1p34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP44   20064
Cards
Entrez_Gene (NCBI)USP44  84101  ubiquitin specific peptidase 44
Aliases
GeneCards (Weizmann)USP44
Ensembl hg19 (Hinxton)ENSG00000136014 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136014 [Gene_View]  chr12:95516560-95548844 [Contig_View]  USP44 [Vega]
ICGC DataPortalENSG00000136014
TCGA cBioPortalUSP44
AceView (NCBI)USP44
Genatlas (Paris)USP44
WikiGenes84101
SOURCE (Princeton)USP44
Genetics Home Reference (NIH)USP44
Genomic and cartography
GoldenPath hg38 (UCSC)USP44  -     chr12:95516560-95548844 -  12q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP44  -     12q22   [Description]    (hg19-Feb_2009)
EnsemblUSP44 - 12q22 [CytoView hg19]  USP44 - 12q22 [CytoView hg38]
Mapping of homologs : NCBIUSP44 [Mapview hg19]  USP44 [Mapview hg38]
OMIM610993   
Gene and transcription
Genbank (Entrez)AA101229 AK027434 AK315697 AL136825 AM392541
RefSeq transcript (Entrez)NM_001042403 NM_001278393 NM_001347936 NM_001347937 NM_032147
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP44
Cluster EST : UnigeneHs.710121 [ NCBI ]
CGAP (NCI)Hs.710121
Alternative Splicing GalleryENSG00000136014
Gene ExpressionUSP44 [ NCBI-GEO ]   USP44 [ EBI - ARRAY_EXPRESS ]   USP44 [ SEEK ]   USP44 [ MEM ]
Gene Expression Viewer (FireBrowse)USP44 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84101
GTEX Portal (Tissue expression)USP44
Human Protein AtlasENSG00000136014-USP44 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0E7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0E7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0E7
Splice isoforms : SwissVarQ9H0E7
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusQ9H0E7
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)    ZF_UBP (PS50271)   
Domains : Interpro (EBI)Peptidase_C19_UCH    USP_CS    USP_dom    Znf_RING/FYVE/PHD    Znf_UBP   
Domain families : Pfam (Sanger)UCH (PF00443)    zf-UBP (PF02148)   
Domain families : Pfam (NCBI)pfam00443    pfam02148   
Domain families : Smart (EMBL)ZnF_UBP (SM00290)  
Conserved Domain (NCBI)USP44
DMDM Disease mutations84101
Blocks (Seattle)USP44
SuperfamilyQ9H0E7
Human Protein Atlas [tissue]ENSG00000136014-USP44 [tissue]
Peptide AtlasQ9H0E7
HPRD15636
IPIIPI00030306   IPI01022557   IPI01022768   IPI01021117   
Protein Interaction databases
DIP (DOE-UCLA)Q9H0E7
IntAct (EBI)Q9H0E7
FunCoupENSG00000136014
BioGRIDUSP44
STRING (EMBL)USP44
ZODIACUSP44
Ontologies - Pathways
QuickGOQ9H0E7
Ontology : AmiGOthiol-dependent ubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  cell cycle  zinc ion binding  protein deubiquitination  protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  regulation of spindle checkpoint  regulation of mitotic cell cycle spindle assembly checkpoint  negative regulation of ubiquitin protein ligase activity  
Ontology : EGO-EBIthiol-dependent ubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  cell cycle  zinc ion binding  protein deubiquitination  protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  regulation of spindle checkpoint  regulation of mitotic cell cycle spindle assembly checkpoint  negative regulation of ubiquitin protein ligase activity  
NDEx NetworkUSP44
Atlas of Cancer Signalling NetworkUSP44
Wikipedia pathwaysUSP44
Orthology - Evolution
OrthoDB84101
GeneTree (enSembl)ENSG00000136014
Phylogenetic Trees/Animal Genes : TreeFamUSP44
HOVERGENQ9H0E7
HOGENOMQ9H0E7
Homologs : HomoloGeneUSP44
Homology/Alignments : Family Browser (UCSC)USP44
Gene fusions - Rearrangements
Fusion: Tumor Portal USP44
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP44 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP44
dbVarUSP44
ClinVarUSP44
1000_GenomesUSP44 
Exome Variant ServerUSP44
ExAC (Exome Aggregation Consortium)ENSG00000136014
GNOMAD BrowserENSG00000136014
Genetic variants : HAPMAP84101
Genomic Variants (DGV)USP44 [DGVbeta]
DECIPHERUSP44 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP44 
Mutations
ICGC Data PortalUSP44 
TCGA Data PortalUSP44 
Broad Tumor PortalUSP44
OASIS PortalUSP44 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP44  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP44
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP44
DgiDB (Drug Gene Interaction Database)USP44
DoCM (Curated mutations)USP44 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP44 (select a term)
intoGenUSP44
Cancer3DUSP44(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610993   
Orphanet
MedgenUSP44
Genetic Testing Registry USP44
NextProtQ9H0E7 [Medical]
TSGene84101
GENETestsUSP44
Target ValidationUSP44
Huge Navigator USP44 [HugePedia]
snp3D : Map Gene to Disease84101
BioCentury BCIQUSP44
ClinGenUSP44
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84101
Chemical/Pharm GKB GenePA134931457
Clinical trialUSP44
Miscellaneous
canSAR (ICR)USP44 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP44
EVEXUSP44
GoPubMedUSP44
iHOPUSP44
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 13:16:57 CET 2017

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