USP44 (ubiquitin specific peptidase 44)

2012-01-01  

Identity

HGNC
LOCATION
12q22
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 84101
MIM: 610993
HGNC: 20064
Ensembl: ENSG00000136014

Variants:

dbSNP: 84101
ClinVar: 84101
TCGA: ENSG00000136014
COSMIC: USP44

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136014ENST00000258499Q9H0E7
ENSG00000136014ENST00000258499A0A024RBD7
ENSG00000136014ENST00000393091Q9H0E7
ENSG00000136014ENST00000393091A0A024RBD7
ENSG00000136014ENST00000537435Q9H0E7
ENSG00000136014ENST00000537435A0A024RBD7
ENSG00000136014ENST00000549639F8VVD6
ENSG00000136014ENST00000551837F8VRW0
ENSG00000136014ENST00000552440F8VRI7

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DeubiquitinationREACTOMER-HSA-5688426
Ub-specific processing proteasesREACTOMER-HSA-5689880

References

Pubmed IDYearTitleCitations
378162582024RNA-binding protein NOVA1 promotes acute T-lymphocyte leukemia progression by stabilizing USP44 mRNA.0
378162582024RNA-binding protein NOVA1 promotes acute T-lymphocyte leukemia progression by stabilizing USP44 mRNA.0
372044802023Integrated network findings reveal ubiquitin-specific protease 44 overexpression suppresses tumorigenicity of liver cancer.1
377522332023MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex.3
372044802023Integrated network findings reveal ubiquitin-specific protease 44 overexpression suppresses tumorigenicity of liver cancer.1
377522332023MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex.3
350790212022USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma.33
364836012022USP44 accelerates the growth of T-cell acute lymphoblastic leukemia through interacting with WDR5 and repressing its ubiquitination.1
350790212022USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma.33
364836012022USP44 accelerates the growth of T-cell acute lymphoblastic leukemia through interacting with WDR5 and repressing its ubiquitination.1
329565922021USP44 hypermethylation promotes cell proliferation and metastasis in breast cancer.8
336474552021CRADD and USP44 mutations in intellectual disability, mild lissencephaly, brain atrophy, developmental delay, strabismus, behavioural problems and skeletal anomalies.5
329565922021USP44 hypermethylation promotes cell proliferation and metastasis in breast cancer.8
336474552021CRADD and USP44 mutations in intellectual disability, mild lissencephaly, brain atrophy, developmental delay, strabismus, behavioural problems and skeletal anomalies.5
319680132020USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA.20

Citation

Dessen P

USP44 (ubiquitin specific peptidase 44)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52539/usp44