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USP45 (ubiquitin specific peptidase 45)

Identity

Alias_namesubiquitin specific protease 45
Alias_symbol (synonym)MGC14793
Other alias-
HGNC (Hugo) USP45
LocusID (NCBI) 85015
Atlas_Id 55158
Location 6q16.2  [Link to chromosome band 6q16]
Location_base_pair Starts at 99482264 and ends at 99515489 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
USP45 (6q16.2) / THOC1 (18p11.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)USP45   20080
Cards
Entrez_Gene (NCBI)USP45  85015  ubiquitin specific peptidase 45
Aliases
GeneCards (Weizmann)USP45
Ensembl hg19 (Hinxton)ENSG00000123552 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123552 [Gene_View]  ENSG00000123552 [Sequence]  chr6:99482264-99515489 [Contig_View]  USP45 [Vega]
ICGC DataPortalENSG00000123552
TCGA cBioPortalUSP45
AceView (NCBI)USP45
Genatlas (Paris)USP45
WikiGenes85015
SOURCE (Princeton)USP45
Genetics Home Reference (NIH)USP45
Genomic and cartography
GoldenPath hg38 (UCSC)USP45  -     chr6:99482264-99515489 -  6q16.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP45  -     6q16.2   [Description]    (hg19-Feb_2009)
EnsemblUSP45 - 6q16.2 [CytoView hg19]  USP45 - 6q16.2 [CytoView hg38]
Mapping of homologs : NCBIUSP45 [Mapview hg19]  USP45 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AJ583819 AK021831 AK123299 AK310643 AL713747
RefSeq transcript (Entrez)NM_001080481 NM_001346021 NM_001346022 NM_001346023 NM_001346024 NM_001346025 NM_001346026 NM_001346027 NM_001346028 NM_001346029 NM_001346030 NM_001346033 NM_032929
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP45
Cluster EST : UnigeneHs.677065 [ NCBI ]
CGAP (NCI)Hs.677065
Alternative Splicing GalleryENSG00000123552
Gene ExpressionUSP45 [ NCBI-GEO ]   USP45 [ EBI - ARRAY_EXPRESS ]   USP45 [ SEEK ]   USP45 [ MEM ]
Gene Expression Viewer (FireBrowse)USP45 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85015
GTEX Portal (Tissue expression)USP45
Human Protein AtlasENSG00000123552-USP45 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ70EL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ70EL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ70EL2
Splice isoforms : SwissVarQ70EL2
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusQ70EL2
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)    ZF_UBP (PS50271)   
Domains : Interpro (EBI)Peptidase_C19_UCH    USP_CS    USP_dom    Znf_RING/FYVE/PHD    Znf_UBP   
Domain families : Pfam (Sanger)UCH (PF00443)    zf-UBP (PF02148)   
Domain families : Pfam (NCBI)pfam00443    pfam02148   
Conserved Domain (NCBI)USP45
DMDM Disease mutations85015
Blocks (Seattle)USP45
SuperfamilyQ70EL2
Human Protein Atlas [tissue]ENSG00000123552-USP45 [tissue]
Peptide AtlasQ70EL2
IPIIPI00738106   IPI00736634   IPI00553181   IPI00966333   IPI00552770   IPI00967505   IPI00966628   IPI00964467   IPI00967279   IPI00964474   
Protein Interaction databases
DIP (DOE-UCLA)Q70EL2
IntAct (EBI)Q70EL2
FunCoupENSG00000123552
BioGRIDUSP45
STRING (EMBL)USP45
ZODIACUSP45
Ontologies - Pathways
QuickGOQ70EL2
Ontology : AmiGOthiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  nucleus  nucleoplasm  cytoplasm  DNA repair  ubiquitin-dependent protein catabolic process  zinc ion binding  protein deubiquitination  protein deubiquitination  global genome nucleotide-excision repair  
Ontology : EGO-EBIthiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  nucleus  nucleoplasm  cytoplasm  DNA repair  ubiquitin-dependent protein catabolic process  zinc ion binding  protein deubiquitination  protein deubiquitination  global genome nucleotide-excision repair  
NDEx NetworkUSP45
Atlas of Cancer Signalling NetworkUSP45
Wikipedia pathwaysUSP45
Orthology - Evolution
OrthoDB85015
GeneTree (enSembl)ENSG00000123552
Phylogenetic Trees/Animal Genes : TreeFamUSP45
HOVERGENQ70EL2
HOGENOMQ70EL2
Homologs : HomoloGeneUSP45
Homology/Alignments : Family Browser (UCSC)USP45
Gene fusions - Rearrangements
Fusion : QuiverUSP45
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP45 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP45
dbVarUSP45
ClinVarUSP45
1000_GenomesUSP45 
Exome Variant ServerUSP45
ExAC (Exome Aggregation Consortium)ENSG00000123552
GNOMAD BrowserENSG00000123552
Varsome BrowserUSP45
Genetic variants : HAPMAP85015
Genomic Variants (DGV)USP45 [DGVbeta]
DECIPHERUSP45 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP45 
Mutations
ICGC Data PortalUSP45 
TCGA Data PortalUSP45 
Broad Tumor PortalUSP45
OASIS PortalUSP45 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP45  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUSP45
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP45
DgiDB (Drug Gene Interaction Database)USP45
DoCM (Curated mutations)USP45 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP45 (select a term)
intoGenUSP45
Cancer3DUSP45(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETUSP45
MedgenUSP45
Genetic Testing Registry USP45
NextProtQ70EL2 [Medical]
TSGene85015
GENETestsUSP45
Target ValidationUSP45
Huge Navigator USP45 [HugePedia]
snp3D : Map Gene to Disease85015
BioCentury BCIQUSP45
ClinGenUSP45
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85015
Chemical/Pharm GKB GenePA134889604
Clinical trialUSP45
Miscellaneous
canSAR (ICR)USP45 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP45
EVEXUSP45
GoPubMedUSP45
iHOPUSP45
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:49:08 CET 2018

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