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USP47 (ubiquitin specific peptidase 47)

Identity

Alias (NCBI)TRFP
HGNC (Hugo) USP47
HGNC Previous nameTrf (TATA binding protein-related factor)-proximal homolog (Drosophila)
 ubiquitin specific protease 47
LocusID (NCBI) 55031
Atlas_Id 51474
Location 11p15.3  [Link to chromosome band 11p15]
Location_base_pair Starts at 11841972 and ends at 11961887 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AFAP1L1 (5q32) / USP47 (11p15.3)AKAP13 (15q25.3) / USP47 (11p15.3)RPS8 (1p34.1) / USP47 (11p15.3)
SEMA3A (7q21.11) / USP47 (11p15.3)USP47 (11p15.3) / DFNB31 (9q32)USP47 (11p15.3) / USP47 (11p15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)USP47   20076
Cards
Entrez_Gene (NCBI)USP47  55031  ubiquitin specific peptidase 47
AliasesTRFP
GeneCards (Weizmann)USP47
Ensembl hg19 (Hinxton)ENSG00000170242 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170242 [Gene_View]  ENSG00000170242 [Sequence]  chr11:11841972-11961887 [Contig_View]  USP47 [Vega]
ICGC DataPortalENSG00000170242
TCGA cBioPortalUSP47
AceView (NCBI)USP47
Genatlas (Paris)USP47
WikiGenes55031
SOURCE (Princeton)USP47
Genetics Home Reference (NIH)USP47
Genomic and cartography
GoldenPath hg38 (UCSC)USP47  -     chr11:11841972-11961887 +  11p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)USP47  -     11p15.3   [Description]    (hg19-Feb_2009)
GoldenPathUSP47 - 11p15.3 [CytoView hg19]  USP47 - 11p15.3 [CytoView hg38]
ImmunoBaseENSG00000170242
genome Data Viewer NCBIUSP47 [Mapview hg19]  
OMIM614460   
Gene and transcription
Genbank (Entrez)AF059318 AI126428 AI693144 AK000734 AK027283
RefSeq transcript (Entrez)NM_001282659 NM_001330208 NM_001372091 NM_001372092 NM_001372093 NM_001372094 NM_001372095 NM_001372096 NM_001372097 NM_001372098 NM_001372099 NM_001372100 NM_001372101 NM_001372102 NM_001372103 NM_017944
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)USP47
Alternative Splicing GalleryENSG00000170242
Gene ExpressionUSP47 [ NCBI-GEO ]   USP47 [ EBI - ARRAY_EXPRESS ]   USP47 [ SEEK ]   USP47 [ MEM ]
Gene Expression Viewer (FireBrowse)USP47 [ Firebrowse - Broad ]
GenevisibleExpression of USP47 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55031
GTEX Portal (Tissue expression)USP47
Human Protein AtlasENSG00000170242-USP47 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96K76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96K76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96K76
Splice isoforms : SwissVarQ96K76
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ96K76
Domaine pattern : Prosite (Expaxy)USP_1 (PS00972)    USP_2 (PS00973)    USP_3 (PS50235)   
Domains : Interpro (EBI)Papain-like_cys_pep_sf    Peptidase_C19_UCH    Ubiquitin-like_domsf    USP_CS    USP_dom   
Domain families : Pfam (Sanger)UCH (PF00443)   
Domain families : Pfam (NCBI)pfam00443   
Conserved Domain (NCBI)USP47
DMDM Disease mutations55031
Blocks (Seattle)USP47
SuperfamilyQ96K76
Human Protein Atlas [tissue]ENSG00000170242-USP47 [tissue]
Peptide AtlasQ96K76
IPIIPI00607554   IPI00165528   IPI00607731   IPI00023584   IPI00985193   IPI00470871   
Protein Interaction databases
DIP (DOE-UCLA)Q96K76
IntAct (EBI)Q96K76
FunCoupENSG00000170242
BioGRIDUSP47
STRING (EMBL)USP47
ZODIACUSP47
Ontologies - Pathways
QuickGOQ96K76
Ontology : AmiGOcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  base-excision repair  ubiquitin-dependent protein catabolic process  cellular response to DNA damage stimulus  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  protein deubiquitination  SCF ubiquitin ligase complex  positive regulation of cell growth  regulation of protein stability  cellular response to UV  monoubiquitinated protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  response to drug  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of transcription, DNA-templated  WD40-repeat domain binding  positive regulation of canonical Wnt signaling pathway  ubiquitinyl hydrolase activity  negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  
Ontology : EGO-EBIcysteine-type endopeptidase activity  thiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  base-excision repair  ubiquitin-dependent protein catabolic process  cellular response to DNA damage stimulus  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  protein deubiquitination  SCF ubiquitin ligase complex  positive regulation of cell growth  regulation of protein stability  cellular response to UV  monoubiquitinated protein deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  response to drug  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of transcription, DNA-templated  WD40-repeat domain binding  positive regulation of canonical Wnt signaling pathway  ubiquitinyl hydrolase activity  negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  
NDEx NetworkUSP47
Atlas of Cancer Signalling NetworkUSP47
Wikipedia pathwaysUSP47
Orthology - Evolution
OrthoDB55031
GeneTree (enSembl)ENSG00000170242
Phylogenetic Trees/Animal Genes : TreeFamUSP47
HOGENOMQ96K76
Homologs : HomoloGeneUSP47
Homology/Alignments : Family Browser (UCSC)USP47
Gene fusions - Rearrangements
Fusion : QuiverUSP47
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUSP47 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)USP47
dbVarUSP47
ClinVarUSP47
MonarchUSP47
1000_GenomesUSP47 
Exome Variant ServerUSP47
GNOMAD BrowserENSG00000170242
Varsome BrowserUSP47
Genetic variants : HAPMAP55031
Genomic Variants (DGV)USP47 [DGVbeta]
DECIPHERUSP47 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUSP47 
Mutations
ICGC Data PortalUSP47 
TCGA Data PortalUSP47 
Broad Tumor PortalUSP47
OASIS PortalUSP47 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUSP47  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUSP47
Mutations and Diseases : HGMDUSP47
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch USP47
DgiDB (Drug Gene Interaction Database)USP47
DoCM (Curated mutations)USP47 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)USP47 (select a term)
intoGenUSP47
Cancer3DUSP47(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614460   
Orphanet
DisGeNETUSP47
MedgenUSP47
Genetic Testing Registry USP47
NextProtQ96K76 [Medical]
TSGene55031
GENETestsUSP47
Target ValidationUSP47
Huge Navigator USP47 [HugePedia]
snp3D : Map Gene to Disease55031
BioCentury BCIQUSP47
ClinGenUSP47
Clinical trials, drugs, therapy
Protein Interactions : CTD55031
Pharm GKB GenePA134880952
Clinical trialUSP47
Miscellaneous
canSAR (ICR)USP47 (select the gene name)
HarmonizomeUSP47
DataMed IndexUSP47
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUSP47
EVEXUSP47
GoPubMedUSP47
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:38:32 CEST 2020
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