USP5 (ubiquitin specific peptidase 5 (isopeptidase T))

Identity

Other names	ISOT
HGNC	USP5
Location	12p13
Location_base_pair	Starts at 6831546 and ends at 6846056 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	USP5   12628
Entrez_Gene	USP5  8078  ubiquitin specific peptidase 5 (isopeptidase T)
	Cards
GeneCards	USP5
Ensembl	ENSG00000111667 [Gene_View]  USP5 [Vega]
Genatlas	USP5
	Genomic and cartography
GoldenPath	USP5  -  12p13   chr12:6831546-6846056 +  12p13.31   [Description]    (hg18-March_2006)
Ensembl	USP5 - 12p13.31 [CytoView]
NCBI	Mapview
OMIM	601447 Disease map [OMIM]
HomoloGene	USP5
	Gene and transcription
Genbank	AI289395 [ ENTREZ ]
Genbank	AK308021 [ ENTREZ ]
Genbank	AU099996 [ ENTREZ ]
Genbank	BC004889 [ ENTREZ ]
Genbank	BC005139 [ ENTREZ ]
RefSeq	NM_001098536 [ SRS ]    NM_001098536 [ ENTREZ ]
RefSeq	NM_003481 [ SRS ]    NM_003481 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	AC_000144 [ SRS ]    AC_000144 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NT_009759 [ SRS ]    NT_009759 [ ENTREZ ]
RefSeq	NW_001838050 [ SRS ]    NW_001838050 [ ENTREZ ]
RefSeq	NW_925295 [ SRS ]    NW_925295 [ ENTREZ ]
CCDS	USP5 CCDS - NCBI
AceView	USP5 AceView - NCBI
Unigene	Hs.631661 [ SRS ]    Hs.631661 [ NCBI ]
Fast-db	1395 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P45974 [ SRS]    P45974 [ EXPASY ]     P45974 [ INTERPRO ]     P45974 [ UNIPROT ] P45974 [ VarSplice FASTA ]
Prosite	PS50030 UBA [ SRS ]    PS50030 UBA [ Expasy ]
Prosite	PS00972 UCH_2_1 [ SRS ]    PS00972 UCH_2_1 [ Expasy ]
Prosite	PS00973 UCH_2_2 [ SRS ]    PS00973 UCH_2_2 [ Expasy ]
Prosite	PS50235 UCH_2_3 [ SRS ]    PS50235 UCH_2_3 [ Expasy ]
Prosite	PS50271 ZF_UBP [ SRS ]    PS50271 ZF_UBP [ Expasy ]
Interpro	IPR001394 Peptidase_C19 [ SRS ]    IPR001394 Peptidase_C19 [ EBI ]
Interpro	IPR000449 UBA/transl_elong_EF1B_N [ SRS ]    IPR000449 UBA/transl_elong_EF1B_N [ EBI ]
Interpro	IPR015940 UBA/transl_elong_EF1B_N_euk [ SRS ]    IPR015940 UBA/transl_elong_EF1B_N_euk [ EBI ]
Interpro	IPR016652 Ubiquitinyl_hydrolase [ SRS ]    IPR016652 Ubiquitinyl_hydrolase [ EBI ]
Interpro	IPR001607 Znf_UBP [ SRS ]    IPR001607 Znf_UBP [ EBI ]
CluSTr	P45974
Pfam	PF00627 UBA [ SRS ]    PF00627 UBA [ Sanger ]    pfam00627 [ NCBI-CDD ]
Pfam	PF00443 UCH [ SRS ]    PF00443 UCH [ Sanger ]    pfam00443 [ NCBI-CDD ]
Pfam	PF02148 zf-UBP [ SRS ]    PF02148 zf-UBP [ Sanger ]    pfam02148 [ NCBI-CDD ]
Smart	SM00165 UBA [EMBL]
Smart	SM00290 ZnF_UBP [EMBL]
Blocks	P45974
PDB	2DAG [ SRS ]    2DAG [ PdbSum ],   2DAG [ IMB ]   2DAG [ RSDB ]
PDB	2DAK [ SRS ]    2DAK [ PdbSum ],   2DAK [ IMB ]   2DAK [ RSDB ]
PDB	2G43 [ SRS ]    2G43 [ PdbSum ],   2G43 [ IMB ]   2G43 [ RSDB ]
PDB	2G45 [ SRS ]    2G45 [ PdbSum ],   2G45 [ IMB ]   2G45 [ RSDB ]
HPRD	03265
	Protein Interaction databases
DIP	P45974
IntAct	P45974
	Polymorphism : SNP, mutations, diseases
OMIM	601447    [ map ]
GENETests	601447
SNP	USP5 [dbSNP-NCBI]
SNP	NM_001098536 [SNP-NCI]
SNP	NM_003481 [SNP-NCI]
SNP	USP5 [GeneSNPs - Utah]  USP5] [HGBASE - SRS]
HAPMAP	USP5 [HAPMAP]
COSMIC	USP5 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	USP5
Genetic Association	USP5
CDC HuGE	USP5
	General knowledge
Family Browser	USP5 [UCSC Family Browser]
SOURCE	NM_001098536
SOURCE	NM_003481
SMD	Hs.631661
SAGE	Hs.631661
Enzyme	3.1.2.15 [ Enzyme-Expasy ]   3.1.2.15 [ Enzyme-SRS ]   3.1.2.15 [ IntEnz-EBI ]   3.1.2.15 [ BRENDA ]   3.1.2.15 [ KEGG ]
GO	cysteine-type endopeptidase activity [Amigo]  cysteine-type endopeptidase activity
GO	protein binding [Amigo]  protein binding
GO	lysosome [Amigo]  lysosome
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	zinc ion binding [Amigo]  zinc ion binding
GO	ubiquitin-specific protease 5 activity [Amigo]  ubiquitin-specific protease 5 activity
GO	metal ion binding [Amigo]  metal ion binding
PubGene	USP5
TreeFam	USP5
CTD	8078 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	USP5 Related clones (RZPD - Berlin)
	PubMed
PubMed	19 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:18:45 2008