USP54 (ubiquitin specific peptidase 54)

2018-02-01  

Identity

HGNC
USP54
LOCATION
10q22.2
LOCUSID
159195
ALIAS
C10orf29,bA137L10.3,bA137L10.4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 159195
HGNC: 23513
Ensembl: ENSG00000166348

Variants:

dbSNP: 159195
ClinVar: 159195
TCGA: ENSG00000166348
COSMIC: USP54

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166348ENST00000339859Q70EL1
ENSG00000166348ENST00000413442X6RH50
ENSG00000166348ENST00000418501H7C296
ENSG00000166348ENST00000422491Q70EL1
ENSG00000166348ENST00000424265H7C1E9
ENSG00000166348ENST00000433394X6RHN7
ENSG00000166348ENST00000451492X6RGF2
ENSG00000166348ENST00000466048R4GN32

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
277690712016The deubiquitinase USP54 is overexpressed in colorectal cancer stem cells and promotes intestinal tumorigenesis.8

Citation

Dessen P

USP54 (ubiquitin specific peptidase 54)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57279/usp54