Identity
HGNC
LOCATION
Xp11.4
LOCUSID
ALIAS
DFFRX,FAF,FAM,MRX99,MRXS99F
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8239
MIM: 300072
HGNC: 12632
Ensembl: ENSG00000124486
Variants:
dbSNP: 8239
ClinVar: 8239
TCGA: ENSG00000124486
COSMIC: USP9X
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000124486 | ENST00000324545 | Q93008 |
| ENSG00000124486 | ENST00000378308 | Q93008 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36330954 | 2023 | Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma. | 3 |
| 36525374 | 2023 | USP9X promotes lipopolysaccharide-stimulated acute lung injury by deubiquitination of NLRP3. | 3 |
| 36995092 | 2023 | KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle. | 1 |
| 37030295 | 2023 | USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities. | 1 |
| 37260183 | 2023 | Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition. | 2 |
| 37314216 | 2023 | USP9X deubiquitinates and stabilizes CDC123 to promote breast carcinogenesis through regulating cell cycle. | 0 |
| 37454738 | 2023 | Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival. | 2 |
| 36330954 | 2023 | Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma. | 3 |
| 36525374 | 2023 | USP9X promotes lipopolysaccharide-stimulated acute lung injury by deubiquitination of NLRP3. | 3 |
| 36995092 | 2023 | KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle. | 1 |
| 37030295 | 2023 | USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities. | 1 |
| 37260183 | 2023 | Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition. | 2 |
| 37314216 | 2023 | USP9X deubiquitinates and stabilizes CDC123 to promote breast carcinogenesis through regulating cell cycle. | 0 |
| 37454738 | 2023 | Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival. | 2 |
| 34606682 | 2022 | DDX3 interacts with USP9X and participates in deubiquitination of the anti-apoptotic protein MCL1. | 3 |
Citation
Dessen P
USP9X (ubiquitin specific peptidase 9 X-linked)
Atlas Genet Cytogenet Oncol Haematol. 2009-09-01
Online version: http://atlasgeneticsoncology.org/gene/51119/usp9x
