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UTP20 (UTP20, small subunit processome component)

Identity

Alias_namesUTP20
Alias_symbol (synonym)DRIM
1A6/DRIM
Other alias
HGNC (Hugo) UTP20
LocusID (NCBI) 27340
Atlas_Id 40363
Location 12q23.2  [Link to chromosome band 12q23]
Location_base_pair Starts at 101280127 and ends at 101386619 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CHPT1 (12q23.2) / UTP20 (12q23.2)UTP20 (12q23.2) / ANKS1B (12q23.1)UTP20 (12q23.2) / UTP20 (12q23.2)
UTP20 12q23.2 / ANKS1B 12q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)UTP20   17897
Cards
Entrez_Gene (NCBI)UTP20  27340  UTP20, small subunit processome component
Aliases1A6/DRIM; DRIM
GeneCards (Weizmann)UTP20
Ensembl hg19 (Hinxton)ENSG00000120800 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120800 [Gene_View]  chr12:101280127-101386619 [Contig_View]  UTP20 [Vega]
ICGC DataPortalENSG00000120800
TCGA cBioPortalUTP20
AceView (NCBI)UTP20
Genatlas (Paris)UTP20
WikiGenes27340
SOURCE (Princeton)UTP20
Genetics Home Reference (NIH)UTP20
Genomic and cartography
GoldenPath hg38 (UCSC)UTP20  -     chr12:101280127-101386619 +  12q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UTP20  -     12q23.2   [Description]    (hg19-Feb_2009)
EnsemblUTP20 - 12q23.2 [CytoView hg19]  UTP20 - 12q23.2 [CytoView hg38]
Mapping of homologs : NCBIUTP20 [Mapview hg19]  UTP20 [Mapview hg38]
OMIM612822   
Gene and transcription
Genbank (Entrez)AA306482 AF072718 AJ006778 AK000333 AK297739
RefSeq transcript (Entrez)NM_014503
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UTP20
Cluster EST : UnigeneHs.295732 [ NCBI ]
CGAP (NCI)Hs.295732
Alternative Splicing GalleryENSG00000120800
Gene ExpressionUTP20 [ NCBI-GEO ]   UTP20 [ EBI - ARRAY_EXPRESS ]   UTP20 [ SEEK ]   UTP20 [ MEM ]
Gene Expression Viewer (FireBrowse)UTP20 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27340
GTEX Portal (Tissue expression)UTP20
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75691   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75691  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75691
Splice isoforms : SwissVarO75691
PhosPhoSitePlusO75691
Domains : Interpro (EBI)ARM-like    ARM-type_fold    DRIM   
Domain families : Pfam (Sanger)DRIM (PF07539)   
Domain families : Pfam (NCBI)pfam07539   
Conserved Domain (NCBI)UTP20
DMDM Disease mutations27340
Blocks (Seattle)UTP20
SuperfamilyO75691
Human Protein AtlasENSG00000120800
Peptide AtlasO75691
HPRD09928
IPIIPI00004970   
Protein Interaction databases
DIP (DOE-UCLA)O75691
IntAct (EBI)O75691
FunCoupENSG00000120800
BioGRIDUTP20
STRING (EMBL)UTP20
ZODIACUTP20
Ontologies - Pathways
QuickGOO75691
Ontology : AmiGOendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  protein binding  nucleoplasm  nucleoplasm  nucleolus  nucleolus  cytoplasm  plasma membrane  rRNA processing  rRNA processing  negative regulation of cell proliferation  90S preribosome  90S preribosome  preribosome, small subunit precursor  small-subunit processome  small-subunit processome  
Ontology : EGO-EBIendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  protein binding  nucleoplasm  nucleoplasm  nucleolus  nucleolus  cytoplasm  plasma membrane  rRNA processing  rRNA processing  negative regulation of cell proliferation  90S preribosome  90S preribosome  preribosome, small subunit precursor  small-subunit processome  small-subunit processome  
NDEx NetworkUTP20
Atlas of Cancer Signalling NetworkUTP20
Wikipedia pathwaysUTP20
Orthology - Evolution
OrthoDB27340
GeneTree (enSembl)ENSG00000120800
Phylogenetic Trees/Animal Genes : TreeFamUTP20
HOVERGENO75691
HOGENOMO75691
Homologs : HomoloGeneUTP20
Homology/Alignments : Family Browser (UCSC)UTP20
Gene fusions - Rearrangements
Fusion : MitelmanCHPT1/UTP20 [12q23.2/12q23.2]  [t(12;12)(q23;q23)]  
Fusion : MitelmanUTP20/ANKS1B [12q23.2/12q23.1]  [t(12;12)(q23;q23)]  
Fusion: TCGAUTP20 12q23.2 ANKS1B 12q23.1 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUTP20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UTP20
dbVarUTP20
ClinVarUTP20
1000_GenomesUTP20 
Exome Variant ServerUTP20
ExAC (Exome Aggregation Consortium)UTP20 (select the gene name)
Genetic variants : HAPMAP27340
Genomic Variants (DGV)UTP20 [DGVbeta]
DECIPHERUTP20 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUTP20 
Mutations
ICGC Data PortalUTP20 
TCGA Data PortalUTP20 
Broad Tumor PortalUTP20
OASIS PortalUTP20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUTP20  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUTP20
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UTP20
DgiDB (Drug Gene Interaction Database)UTP20
DoCM (Curated mutations)UTP20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UTP20 (select a term)
intoGenUTP20
Cancer3DUTP20(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612822   
Orphanet
MedgenUTP20
Genetic Testing Registry UTP20
NextProtO75691 [Medical]
TSGene27340
GENETestsUTP20
Target ValidationUTP20
Huge Navigator UTP20 [HugePedia]
snp3D : Map Gene to Disease27340
BioCentury BCIQUTP20
ClinGenUTP20
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27340
Chemical/Pharm GKB GenePA143485666
Clinical trialUTP20
Miscellaneous
canSAR (ICR)UTP20 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUTP20
EVEXUTP20
GoPubMedUTP20
iHOPUTP20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:11:24 CEST 2017

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