UTY (ubiquitously transcribed tetratricopeptide repeat containing, Y-linked)

2018-07-01  

Identity

HGNC
LOCATION
Yq11.221
LOCUSID
ALIAS
KDM6AL,KDM6C,UTY1
FUSION GENES

Other Information

Locus ID:

NCBI: 7404
MIM: 400009
HGNC: 12638
Ensembl: ENSG00000183878

Variants:

dbSNP: 7404
ClinVar: 7404
TCGA: ENSG00000183878
COSMIC: UTY

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183878ENST00000329134O14607
ENSG00000183878ENST00000331397O14607
ENSG00000183878ENST00000362096O14607
ENSG00000183878ENST00000382893A6NCS7
ENSG00000183878ENST00000382896O14607
ENSG00000183878ENST00000537580A0A096LPD8
ENSG00000183878ENST00000538878F5H3N7
ENSG00000183878ENST00000540140F5GWV3
ENSG00000183878ENST00000545955F5H8B4
ENSG00000183878ENST00000612274A0A087X2I9
ENSG00000183878ENST00000617789A0A087X0Y2
ENSG00000183878ENST00000618474A0A087X248
ENSG00000183878ENST00000624098O14607

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HDMs demethylate histonesREACTOMER-HSA-3214842

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
247983372014Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase.47
185116972008Genetic variants of Y chromosome are associated with a protective lipid profile in black men.12
275330812016Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer.6
310973642019Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.0

Citation

Dessen P

UTY (ubiquitously transcribed tetratricopeptide repeat containing, Y-linked)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57388/uty