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UVRAG (UV radiation resistance associated)

Identity

Alias (NCBI)DHTX
VPS38
p63
HGNC (Hugo) UVRAG
HGNC Alias symbVPS38
HGNC Alias namebeclin 1 binding protein
HGNC Previous nameUV radiation resistance associated gene
LocusID (NCBI) 7405
Atlas_Id 42778
Location 11q13.5  [Link to chromosome band 11q13]
Location_base_pair Starts at 75815210 and ends at 76144232 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACER3 (11q13.5)::UVRAG (11q13.5)ARRB1 (11q13.4)::UVRAG (11q13.5)EMSY (11q13.5)::UVRAG (11q13.5)
FAM168A (11q13.4)::UVRAG (11q13.5)LRP5 (11q13.2)::UVRAG (11q13.5)LRTOMT (11q13.4)::UVRAG (11q13.5)
MED27 (9q34.13)::UVRAG (11q13.5)MTHFD1 (14q23.3)::UVRAG (11q13.5)PGM2L1 (11q13.4)::UVRAG (11q13.5)
POLB (8p11.21)::UVRAG (11q13.5)PPME1 (11q13.4)::UVRAG (11q13.5)RAD51B (14q24.1)::UVRAG (11q13.5)
UVRAG (11q13.5)::DGAT2 (11q13.5)UVRAG (11q13.5)::FAM168A (11q13.4)UVRAG (11q13.5)::INTS4 (11q14.1)
UVRAG (11q13.5)::KCNE3 (11q13.4)UVRAG (11q13.5)::KIRREL3 (11q24.2)UVRAG (11q13.5)::LRTOMT (11q13.4)
UVRAG (11q13.5)::MAP6 (11q13.5)UVRAG (11q13.5)::MOGAT2 (11q13.5)UVRAG (11q13.5)::PAK1 (11q13.5)
UVRAG (11q13.5)::RAD51B (14q24.1)UVRAG (11q13.5)::TRIM29 (11q23.3)UVRAG (11q13.5)::ZMAT4 (8p11.21)
cytochrome_b ()::UVRAG (11q13.5)ACER3 11q13.5::UVRAG 11q13.5ARRB1 11q13.4::UVRAG 11q13.5
C11orf30 11q13.5::UVRAG 11q13.5FAM168A 11q13.4::UVRAG 11q13.5LRP5 11q13.2::UVRAG 11q13.5
LRTOMT 11q13.4::UVRAG 11q13.5PGM2L1 11q13.4::UVRAG 11q13.5POLB 8p11.21::UVRAG 11q13.5
PPME1 11q13.4::UVRAG 11q13.5RAD51B 14q24.1::UVRAG 11q13.5UVRAG 11q13.5::DGAT2 11q13.5
UVRAG 11q13.5::FAM168A 11q13.4UVRAG 11q13.5::INTS4 11q14.1UVRAG 11q13.5::KCNE3 11q13.4
UVRAG 11q13.5::KIRREL3 11q24.2UVRAG 11q13.5::LRTOMT 11q13.4UVRAG 11q13.5::MAP6 11q13.5
UVRAG 11q13.5::PAK1 11q13.5UVRAG 11q13.5::RAD51B 14q24.1UVRAG 11q13.5::TRIM29 11q23.3
UVRAG 11q13.5::ZMAT4 8p11.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)UVRAG   12640
Cards
Entrez_Gene (NCBI)UVRAG    UV radiation resistance associated
AliasesDHTX; VPS38; p63
GeneCards (Weizmann)UVRAG
Ensembl hg19 (Hinxton)ENSG00000198382 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198382 [Gene_View]  ENSG00000198382 [Sequence]  chr11:75815210-76144232 [Contig_View]  UVRAG [Vega]
ICGC DataPortalENSG00000198382
TCGA cBioPortalUVRAG
AceView (NCBI)UVRAG
Genatlas (Paris)UVRAG
SOURCE (Princeton)UVRAG
Genetics Home Reference (NIH)UVRAG
Genomic and cartography
GoldenPath hg38 (UCSC)UVRAG  -     chr11:75815210-76144232 +  11q13.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UVRAG  -     11q13.5   [Description]    (hg19-Feb_2009)
GoldenPathUVRAG - 11q13.5 [CytoView hg19]  UVRAG - 11q13.5 [CytoView hg38]
ImmunoBaseENSG00000198382
Genome Data Viewer NCBIUVRAG [Mapview hg19]  
OMIM602493   
Gene and transcription
Genbank (Entrez)AB012958 AK095352 AK222772 AK291011 AK293782
RefSeq transcript (Entrez)NM_001386671 NM_001386672 NM_001386673 NM_001386674 NM_003369
Consensus coding sequences : CCDS (NCBI)UVRAG
Gene ExpressionUVRAG [ NCBI-GEO ]   UVRAG [ EBI - ARRAY_EXPRESS ]   UVRAG [ SEEK ]   UVRAG [ MEM ]
Gene Expression Viewer (FireBrowse)UVRAG [ Firebrowse - Broad ]
GenevisibleExpression of UVRAG in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7405
GTEX Portal (Tissue expression)UVRAG
Human Protein AtlasENSG00000198382-UVRAG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2Y5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2Y5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2Y5
PhosPhoSitePlusQ9P2Y5
Domaine pattern : Prosite (Expaxy)C2 (PS50004)   
Domains : Interpro (EBI)C2_dom    C2_domain_sf    UV_resistance/autophagy_Atg14   
Domain families : Pfam (Sanger)Atg14 (PF10186)   
Domain families : Pfam (NCBI)pfam10186   
Domain families : Smart (EMBL)C2 (SM00239)  
Conserved Domain (NCBI)UVRAG
SuperfamilyQ9P2Y5
AlphaFold pdb e-kbQ9P2Y5   
Human Protein Atlas [tissue]ENSG00000198382-UVRAG [tissue]
HPRD03929
Protein Interaction databases
DIP (DOE-UCLA)Q9P2Y5
IntAct (EBI)Q9P2Y5
BioGRIDUVRAG
STRING (EMBL)UVRAG
ZODIACUVRAG
Ontologies - Pathways
QuickGOQ9P2Y5
Ontology : AmiGOSNARE binding  lytic vacuole  autophagosome membrane  chromosome, centromeric region  protein binding  cytoplasm  lysosome  endosome  early endosome  late endosome  endoplasmic reticulum  centrosome  DNA repair  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  autophagy  spindle organization  chromosome segregation  centrosome cycle  SH3 domain binding  midbody  regulation of cytokinesis  receptor catabolic process  SNARE complex assembly  phagocytic vesicle  viral entry into host cell  maintenance of Golgi location  regulation of protein serine/threonine kinase activity  multivesicular body sorting pathway  autophagosome maturation  double-strand break repair via classical nonhomologous end joining  positive regulation of autophagosome maturation  
Ontology : EGO-EBISNARE binding  lytic vacuole  autophagosome membrane  chromosome, centromeric region  protein binding  cytoplasm  lysosome  endosome  early endosome  late endosome  endoplasmic reticulum  centrosome  DNA repair  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  autophagy  spindle organization  chromosome segregation  centrosome cycle  SH3 domain binding  midbody  regulation of cytokinesis  receptor catabolic process  SNARE complex assembly  phagocytic vesicle  viral entry into host cell  maintenance of Golgi location  regulation of protein serine/threonine kinase activity  multivesicular body sorting pathway  autophagosome maturation  double-strand break repair via classical nonhomologous end joining  positive regulation of autophagosome maturation  
NDEx NetworkUVRAG
Atlas of Cancer Signalling NetworkUVRAG
Wikipedia pathwaysUVRAG
Orthology - Evolution
OrthoDB7405
GeneTree (enSembl)ENSG00000198382
Phylogenetic Trees/Animal Genes : TreeFamUVRAG
Homologs : HomoloGeneUVRAG
Homology/Alignments : Family Browser (UCSC)UVRAG
Gene fusions - Rearrangements
Fusion : MitelmanACER3::UVRAG [11q13.5/11q13.5]  
Fusion : MitelmanARRB1::UVRAG [11q13.4/11q13.5]  
Fusion : MitelmanC11orf30::UVRAG [11q13.5/11q13.5]  
Fusion : MitelmanFAM168A::UVRAG [11q13.4/11q13.5]  
Fusion : MitelmanLRP5::UVRAG [11q13.2/11q13.5]  
Fusion : MitelmanLRTOMT::UVRAG [11q13.4/11q13.5]  
Fusion : MitelmanPGM2L1::UVRAG [11q13.4/11q13.5]  
Fusion : MitelmanPOLB::UVRAG [8p11.21/11q13.5]  
Fusion : MitelmanPPME1::UVRAG [11q13.4/11q13.5]  
Fusion : MitelmanRAD51B::UVRAG [14q24.1/11q13.5]  
Fusion : MitelmanUVRAG::DGAT2 [11q13.5/11q13.5]  
Fusion : MitelmanUVRAG::FAM168A [11q13.5/11q13.4]  
Fusion : MitelmanUVRAG::INTS4 [11q13.5/11q14.1]  
Fusion : MitelmanUVRAG::KCNE3 [11q13.5/11q13.4]  
Fusion : MitelmanUVRAG::KIRREL3 [11q13.5/11q24.2]  
Fusion : MitelmanUVRAG::LRTOMT [11q13.5/11q13.4]  
Fusion : MitelmanUVRAG::MAP6 [11q13.5/11q13.5]  
Fusion : MitelmanUVRAG::PAK1 [11q13.5/11q13.5]  
Fusion : MitelmanUVRAG::RAD51B [11q13.5/14q24.1]  
Fusion : MitelmanUVRAG::TRIM29 [11q13.5/11q23.3]  
Fusion : MitelmanUVRAG::ZMAT4 [11q13.5/8p11.21]  
Fusion Cancer (Beijing)cytochrome_b [UVRAG]  -  11q13.5 [FUSC000405]
Fusion : QuiverUVRAG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUVRAG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UVRAG
dbVarUVRAG
ClinVarUVRAG
MonarchUVRAG
1000_GenomesUVRAG 
Exome Variant ServerUVRAG
GNOMAD BrowserENSG00000198382
Varsome BrowserUVRAG
ACMGUVRAG variants
VarityQ9P2Y5
Genomic Variants (DGV)UVRAG [DGVbeta]
DECIPHERUVRAG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUVRAG 
Mutations
ICGC Data PortalUVRAG 
TCGA Data PortalUVRAG 
Broad Tumor PortalUVRAG
OASIS PortalUVRAG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUVRAG  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUVRAG
Mutations and Diseases : HGMDUVRAG
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaUVRAG
DgiDB (Drug Gene Interaction Database)UVRAG
DoCM (Curated mutations)UVRAG
CIViC (Clinical Interpretations of Variants in Cancer)UVRAG
Cancer3DUVRAG
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602493   
Orphanet
DisGeNETUVRAG
MedgenUVRAG
Genetic Testing Registry UVRAG
NextProtQ9P2Y5 [Medical]
GENETestsUVRAG
Target ValidationUVRAG
Huge Navigator UVRAG [HugePedia]
ClinGenUVRAG
Clinical trials, drugs, therapy
MyCancerGenomeUVRAG
Protein Interactions : CTDUVRAG
Pharm GKB GenePA37264
PharosQ9P2Y5
Clinical trialUVRAG
Miscellaneous
canSAR (ICR)UVRAG
HarmonizomeUVRAG
ARCHS4UVRAG
DataMed IndexUVRAG
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXUVRAG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 18:40:17 CET 2022

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