Atlas of Genetics and Cytogenetics in Oncology and Haematology


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UXS1 (UDP-glucuronate decarboxylase 1)

Identity

Alias_symbol (synonym)FLJ23591
UGD
SDR6E1
Other alias
HGNC (Hugo) UXS1
LocusID (NCBI) 80146
Atlas_Id 75578
Location 2q12.2  [Link to chromosome band 2q12]
Location_base_pair Starts at 106093303 and ends at 106194339 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
UXS1 (2q12.2) / PCBP2 (12q13.13)UXS1 (2q12.2) / VTI1A (10q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UXS1   17729
Cards
Entrez_Gene (NCBI)UXS1  80146  UDP-glucuronate decarboxylase 1
AliasesSDR6E1; UGD
GeneCards (Weizmann)UXS1
Ensembl hg19 (Hinxton)ENSG00000115652 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115652 [Gene_View]  chr2:106093303-106194339 [Contig_View]  UXS1 [Vega]
ICGC DataPortalENSG00000115652
TCGA cBioPortalUXS1
AceView (NCBI)UXS1
Genatlas (Paris)UXS1
WikiGenes80146
SOURCE (Princeton)UXS1
Genetics Home Reference (NIH)UXS1
Genomic and cartography
GoldenPath hg38 (UCSC)UXS1  -     chr2:106093303-106194339 -  2q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UXS1  -     2q12.2   [Description]    (hg19-Feb_2009)
EnsemblUXS1 - 2q12.2 [CytoView hg19]  UXS1 - 2q12.2 [CytoView hg38]
Mapping of homologs : NCBIUXS1 [Mapview hg19]  UXS1 [Mapview hg38]
OMIM609749   
Gene and transcription
Genbank (Entrez)AI217133 AK027244 AK056022 AK057242 AK075120
RefSeq transcript (Entrez)NM_001253875 NM_001253876 NM_025076
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UXS1
Cluster EST : UnigeneHs.743389 [ NCBI ]
CGAP (NCI)Hs.743389
Alternative Splicing GalleryENSG00000115652
Gene ExpressionUXS1 [ NCBI-GEO ]   UXS1 [ EBI - ARRAY_EXPRESS ]   UXS1 [ SEEK ]   UXS1 [ MEM ]
Gene Expression Viewer (FireBrowse)UXS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80146
GTEX Portal (Tissue expression)UXS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBZ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBZ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBZ7
Splice isoforms : SwissVarQ8NBZ7
Catalytic activity : Enzyme4.1.1.35 [ Enzyme-Expasy ]   4.1.1.354.1.1.35 [ IntEnz-EBI ]   4.1.1.35 [ BRENDA ]   4.1.1.35 [ KEGG ]   
PhosPhoSitePlusQ8NBZ7
Domains : Interpro (EBI)NAD(P)-bd_dom    UXS1_N   
Domain families : Pfam (Sanger)GDP_Man_Dehyd (PF16363)    UXS1_N (PF11803)   
Domain families : Pfam (NCBI)pfam16363    pfam11803   
Conserved Domain (NCBI)UXS1
DMDM Disease mutations80146
Blocks (Seattle)UXS1
PDB (SRS)2B69    4GLL    4LK3    4M55   
PDB (PDBSum)2B69    4GLL    4LK3    4M55   
PDB (IMB)2B69    4GLL    4LK3    4M55   
PDB (RSDB)2B69    4GLL    4LK3    4M55   
Structural Biology KnowledgeBase2B69    4GLL    4LK3    4M55   
SCOP (Structural Classification of Proteins)2B69    4GLL    4LK3    4M55   
CATH (Classification of proteins structures)2B69    4GLL    4LK3    4M55   
SuperfamilyQ8NBZ7
Human Protein AtlasENSG00000115652
Peptide AtlasQ8NBZ7
HPRD15642
IPIIPI00657807   IPI00410544   IPI00658111   IPI00910001   IPI00916527   IPI00916638   IPI00916816   IPI00915766   
Protein Interaction databases
DIP (DOE-UCLA)Q8NBZ7
IntAct (EBI)Q8NBZ7
FunCoupENSG00000115652
BioGRIDUXS1
STRING (EMBL)UXS1
ZODIACUXS1
Ontologies - Pathways
QuickGOQ8NBZ7
Ontology : AmiGOcytoplasm  mitochondrion  integral component of membrane  Golgi cisterna membrane  UDP-D-xylose biosynthetic process  protein homodimerization activity  UDP-glucuronate decarboxylase activity  protein tetramerization  extracellular exosome  NAD+ binding  
Ontology : EGO-EBIcytoplasm  mitochondrion  integral component of membrane  Golgi cisterna membrane  UDP-D-xylose biosynthetic process  protein homodimerization activity  UDP-glucuronate decarboxylase activity  protein tetramerization  extracellular exosome  NAD+ binding  
Pathways : KEGGStarch and sucrose metabolism    Amino sugar and nucleotide sugar metabolism   
NDEx NetworkUXS1
Atlas of Cancer Signalling NetworkUXS1
Wikipedia pathwaysUXS1
Orthology - Evolution
OrthoDB80146
GeneTree (enSembl)ENSG00000115652
Phylogenetic Trees/Animal Genes : TreeFamUXS1
HOVERGENQ8NBZ7
HOGENOMQ8NBZ7
Homologs : HomoloGeneUXS1
Homology/Alignments : Family Browser (UCSC)UXS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUXS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UXS1
dbVarUXS1
ClinVarUXS1
1000_GenomesUXS1 
Exome Variant ServerUXS1
ExAC (Exome Aggregation Consortium)UXS1 (select the gene name)
Genetic variants : HAPMAP80146
Genomic Variants (DGV)UXS1 [DGVbeta]
DECIPHERUXS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUXS1 
Mutations
ICGC Data PortalUXS1 
TCGA Data PortalUXS1 
Broad Tumor PortalUXS1
OASIS PortalUXS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUXS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUXS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch UXS1
DgiDB (Drug Gene Interaction Database)UXS1
DoCM (Curated mutations)UXS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UXS1 (select a term)
intoGenUXS1
Cancer3DUXS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609749   
Orphanet
MedgenUXS1
Genetic Testing Registry UXS1
NextProtQ8NBZ7 [Medical]
TSGene80146
GENETestsUXS1
Target ValidationUXS1
Huge Navigator UXS1 [HugePedia]
snp3D : Map Gene to Disease80146
BioCentury BCIQUXS1
ClinGenUXS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80146
Chemical/Pharm GKB GenePA38465
Clinical trialUXS1
Miscellaneous
canSAR (ICR)UXS1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUXS1
EVEXUXS1
GoPubMedUXS1
iHOPUXS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 18 13:43:29 CEST 2017

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