Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8409
MIM: 300234
HGNC: 12641
Ensembl: ENSG00000126756
Variants:
dbSNP: 8409
ClinVar: 8409
TCGA: ENSG00000126756
COSMIC: UXT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000126756 | ENST00000333119 | Q9UBK9 |
| ENSG00000126756 | ENST00000335890 | Q9UBK9 |
| ENSG00000126756 | ENST00000485641 | S4R2Z4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37468105 | 2023 | MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape. | 1 |
| 37468105 | 2023 | MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape. | 1 |
| 34767964 | 2022 | HOXD9 transcriptionally induced UXT facilitate breast cancer progression via epigenetic modification of RND3. | 2 |
| 35217267 | 2022 | Prefoldin and prefoldin-like complex subunits as predictive biomarkers for hepatocellular carcinoma immunotherapy. | 2 |
| 34767964 | 2022 | HOXD9 transcriptionally induced UXT facilitate breast cancer progression via epigenetic modification of RND3. | 2 |
| 35217267 | 2022 | Prefoldin and prefoldin-like complex subunits as predictive biomarkers for hepatocellular carcinoma immunotherapy. | 2 |
| 32744119 | 2021 | Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. | 6 |
| 33010352 | 2021 | The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway. | 7 |
| 33782410 | 2021 | UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy. | 6 |
| 32744119 | 2021 | Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. | 6 |
| 33010352 | 2021 | The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway. | 7 |
| 33782410 | 2021 | UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy. | 6 |
| 31481081 | 2019 | Ubiquitous expressed transcript promotes tumorigenesis by acting as a positive modulator of the polycomb repressive complex 2 in clear cell renal cell carcinoma. | 4 |
| 31481081 | 2019 | Ubiquitous expressed transcript promotes tumorigenesis by acting as a positive modulator of the polycomb repressive complex 2 in clear cell renal cell carcinoma. | 4 |
| 28106301 | 2017 | UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells. | 13 |
Citation
Dessen P
UXT (ubiquitously expressed prefoldin like chaperone)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42779/uxt
