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VAC14 (Vac14, PIKFYVE complex component)

Identity

Other namesArPIKfyve
TAX1BP2
TRX
HGNC (Hugo) VAC14
LocusID (NCBI) 55697
Atlas_Id 53316
Location 16q22.1
Location_base_pair Starts at 70721342 and ends at 70835061 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
COG4 (16q22.1) / VAC14 (16q22.1)MTSS1L (16q22.1) / VAC14 (16q22.1)UBE2G1 (17p13.2) / VAC14 (16q22.1)
VAC14 (16q22.1) / CDH8 (16q21)VAC14 (16q22.1) / CENPT (16q22.1)VAC14 (16q22.1) / VAC14 (16q22.1)
VAC14 (16q22.1) / WWOX (16q23.1)MTSS1L 16q22.1 / VAC14 16q22.1VAC14 16q22.1 / CDH8 16q21
VAC14 16q22.1 / WWOX 16q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VAC14   25507
Cards
Entrez_Gene (NCBI)VAC14  55697  Vac14, PIKFYVE complex component
GeneCards (Weizmann)VAC14
Ensembl hg19 (Hinxton)ENSG00000103043 [Gene_View]  chr16:70721342-70835061 [Contig_View]  VAC14 [Vega]
Ensembl hg38 (Hinxton)ENSG00000103043 [Gene_View]  chr16:70721342-70835061 [Contig_View]  VAC14 [Vega]
ICGC DataPortalENSG00000103043
TCGA cBioPortalVAC14
AceView (NCBI)VAC14
Genatlas (Paris)VAC14
WikiGenes55697
SOURCE (Princeton)VAC14
Genomic and cartography
GoldenPath hg19 (UCSC)VAC14  -     chr16:70721342-70835061 -  16q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)VAC14  -     16q22.1   [Description]    (hg38-Dec_2013)
EnsemblVAC14 - 16q22.1 [CytoView hg19]  VAC14 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBIVAC14 [Mapview hg19]  VAC14 [Mapview hg38]
OMIM604632   
Gene and transcription
Genbank (Entrez)AK001167 AK025479 AK056433 AK090627 AK093941
RefSeq transcript (Entrez)NM_018052
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)VAC14
Cluster EST : UnigeneHs.445061 [ NCBI ]
CGAP (NCI)Hs.445061
Alternative Splicing : Fast-db (Paris)GSHG0011955
Alternative Splicing GalleryENSG00000103043
Gene ExpressionVAC14 [ NCBI-GEO ]   VAC14 [ EBI - ARRAY_EXPRESS ]   VAC14 [ SEEK ]   VAC14 [ MEM ]
Gene Expression Viewer (FireBrowse)VAC14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)55697
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ08AM6 (Uniprot)
NextProtQ08AM6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ08AM6
Splice isoforms : SwissVarQ08AM6 (Swissvar)
PhosPhoSitePlusQ08AM6
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Vac14    Vac14_Fab1-bd    VAC14_Fig4p-bd   
Domain families : Pfam (Sanger)Vac14_Fab1_bd (PF12755)    Vac14_Fig4_bd (PF11916)   
Domain families : Pfam (NCBI)pfam12755    pfam11916   
DMDM Disease mutations55697
Blocks (Seattle)VAC14
SuperfamilyQ08AM6
Human Protein AtlasENSG00000103043
Peptide AtlasQ08AM6
HPRD07660
IPIIPI00025160   IPI00642338   
Protein Interaction databases
DIP (DOE-UCLA)Q08AM6
IntAct (EBI)Q08AM6
FunCoupENSG00000103043
BioGRIDVAC14
STRING (EMBL)VAC14
ZODIACVAC14
Ontologies - Pathways
QuickGOQ08AM6
Ontology : AmiGOGolgi membrane  receptor activity  protein binding  endoplasmic reticulum  phosphatidylinositol biosynthetic process  signal transduction  endosome membrane  viral process  early endosome membrane  late endosome membrane  regulation of lipid kinase activity  PAS complex  
Ontology : EGO-EBIGolgi membrane  receptor activity  protein binding  endoplasmic reticulum  phosphatidylinositol biosynthetic process  signal transduction  endosome membrane  viral process  early endosome membrane  late endosome membrane  regulation of lipid kinase activity  PAS complex  
Pathways : KEGGHTLV-I infection    Viral carcinogenesis   
NDEx Network
Atlas of Cancer Signalling NetworkVAC14
Wikipedia pathwaysVAC14
Orthology - Evolution
OrthoDB55697
GeneTree (enSembl)ENSG00000103043
Phylogenetic Trees/Animal Genes : TreeFamVAC14
Homologs : HomoloGeneVAC14
Homology/Alignments : Family Browser (UCSC)VAC14
Gene fusions - Rearrangements
Fusion: TCGAMTSS1L 16q22.1 VAC14 16q22.1 LUSC
Fusion: TCGAVAC14 16q22.1 CDH8 16q21 SKCM
Fusion: TCGAVAC14 16q22.1 WWOX 16q23.1 BLCA
Polymorphisms : SNP, variants
NCBI Variation ViewerVAC14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VAC14
dbVarVAC14
ClinVarVAC14
1000_GenomesVAC14 
Exome Variant ServerVAC14
ExAC (Exome Aggregation Consortium)VAC14 (select the gene name)
SNP (GeneSNP Utah)VAC14
SNP : HGBaseVAC14
Genetic variants : HAPMAPVAC14
Genomic Variants (DGV)VAC14 [DGVbeta]
Mutations
ICGC Data PortalVAC14 
TCGA Data PortalVAC14 
Broad Tumor PortalVAC14
OASIS PortalVAC14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVAC14 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VAC14
DgiDB (Drug Gene Interaction Database)VAC14
DoCM (Curated mutations)VAC14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VAC14 (select a term)
intoGenVAC14
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:70721342-70835061
CONAN: Copy Number AnalysisVAC14 
Mutations and Diseases : HGMDVAC14
OMIM604632   
MedgenVAC14
Genetic Testing Registry VAC14
NextProtQ08AM6 [Medical]
TSGene55697
GENETestsVAC14
Huge Navigator VAC14 [HugePedia]  VAC14 [HugeCancerGEM]
snp3D : Map Gene to Disease55697
BioCentury BCIQVAC14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55697
Chemical/Pharm GKB GenePA142670633
Clinical trialVAC14
Miscellaneous
canSAR (ICR)VAC14 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVAC14
GoPubMedVAC14
iHOPVAC14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Apr 16 18:09:38 CEST 2016

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