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VAMP3 (vesicle associated membrane protein 3)

Identity

Alias_symbol (synonym)CEB
Other alias
HGNC (Hugo) VAMP3
LocusID (NCBI) 9341
Atlas_Id 42780
Location 1p36.23  [Link to chromosome band 1p36]
Location_base_pair Starts at 7771269 and ends at 7781432 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PANK2 (20p13) / VAMP3 (1p36.23)RERE (1p36.23) / VAMP3 (1p36.23)VAMP3 (1p36.23) / VAMP3 (1p36.23)
RERE 1p36.23 / VAMP3 1p36.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;11)(q14;q23) KMT2A/PICALM::inv(11)(q14q23) KMT2A/PICALM


External links

Nomenclature
HGNC (Hugo)VAMP3   12644
Cards
Entrez_Gene (NCBI)VAMP3  9341  vesicle associated membrane protein 3
AliasesCEB
GeneCards (Weizmann)VAMP3
Ensembl hg19 (Hinxton)ENSG00000049245 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000049245 [Gene_View]  chr1:7771269-7781432 [Contig_View]  VAMP3 [Vega]
ICGC DataPortalENSG00000049245
TCGA cBioPortalVAMP3
AceView (NCBI)VAMP3
Genatlas (Paris)VAMP3
WikiGenes9341
SOURCE (Princeton)VAMP3
Genetics Home Reference (NIH)VAMP3
Genomic and cartography
GoldenPath hg38 (UCSC)VAMP3  -     chr1:7771269-7781432 +  1p36.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VAMP3  -     1p36.23   [Description]    (hg19-Feb_2009)
EnsemblVAMP3 - 1p36.23 [CytoView hg19]  VAMP3 - 1p36.23 [CytoView hg38]
Mapping of homologs : NCBIVAMP3 [Mapview hg19]  VAMP3 [Mapview hg38]
OMIM603657   
Gene and transcription
Genbank (Entrez)AK316558 BC003570 BC005941 BC007050 BT007327
RefSeq transcript (Entrez)NM_004781
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VAMP3
Cluster EST : UnigeneHs.66708 [ NCBI ]
CGAP (NCI)Hs.66708
Alternative Splicing GalleryENSG00000049245
Gene ExpressionVAMP3 [ NCBI-GEO ]   VAMP3 [ EBI - ARRAY_EXPRESS ]   VAMP3 [ SEEK ]   VAMP3 [ MEM ]
Gene Expression Viewer (FireBrowse)VAMP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9341
GTEX Portal (Tissue expression)VAMP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15836   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15836  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15836
Splice isoforms : SwissVarQ15836
PhosPhoSitePlusQ15836
Domaine pattern : Prosite (Expaxy)SYNAPTOBREVIN (PS00417)    V_SNARE (PS50892)   
Domains : Interpro (EBI)Synaptobrevin    Synaptobrevin/VAMP   
Domain families : Pfam (Sanger)Synaptobrevin (PF00957)   
Domain families : Pfam (NCBI)pfam00957   
Conserved Domain (NCBI)VAMP3
DMDM Disease mutations9341
Blocks (Seattle)VAMP3
SuperfamilyQ15836
Human Protein AtlasENSG00000049245
Peptide AtlasQ15836
HPRD04711
Protein Interaction databases
DIP (DOE-UCLA)Q15836
IntAct (EBI)Q15836
FunCoupENSG00000049245
BioGRIDVAMP3
STRING (EMBL)VAMP3
ZODIACVAMP3
Ontologies - Pathways
QuickGOQ15836
Ontology : AmiGOSNARE binding  positive regulation of receptor recycling  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  SNAP receptor activity  protein binding  intracellular  cytosol  plasma membrane  plasma membrane  protein complex assembly  exocytosis  vesicle docking involved in exocytosis  vesicle fusion  cell surface  integral component of membrane  vesicle-mediated transport  apical plasma membrane  syntaxin-1 binding  calcium ion regulated exocytosis  cell junction  transport vesicle  clathrin-coated vesicle  secretory granule  clathrin-coated vesicle membrane  phagocytic vesicle membrane  SNARE complex  trans-Golgi network membrane  substrate adhesion-dependent cell spreading  SNARE complex assembly  retrograde transport, endosome to Golgi  Golgi to plasma membrane protein transport  neuron projection  intracellular membrane-bounded organelle  synapse  perinuclear region of cytoplasm  positive regulation of immunoglobulin secretion  recycling endosome  recycling endosome membrane  membrane organization  membrane fusion  mucus secretion  negative regulation of secretion by cell  regulation of histamine secretion by mast cell  
Ontology : EGO-EBISNARE binding  positive regulation of receptor recycling  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  SNAP receptor activity  protein binding  intracellular  cytosol  plasma membrane  plasma membrane  protein complex assembly  exocytosis  vesicle docking involved in exocytosis  vesicle fusion  cell surface  integral component of membrane  vesicle-mediated transport  apical plasma membrane  syntaxin-1 binding  calcium ion regulated exocytosis  cell junction  transport vesicle  clathrin-coated vesicle  secretory granule  clathrin-coated vesicle membrane  phagocytic vesicle membrane  SNARE complex  trans-Golgi network membrane  substrate adhesion-dependent cell spreading  SNARE complex assembly  retrograde transport, endosome to Golgi  Golgi to plasma membrane protein transport  neuron projection  intracellular membrane-bounded organelle  synapse  perinuclear region of cytoplasm  positive regulation of immunoglobulin secretion  recycling endosome  recycling endosome membrane  membrane organization  membrane fusion  mucus secretion  negative regulation of secretion by cell  regulation of histamine secretion by mast cell  
Pathways : KEGGSNARE interactions in vesicular transport    Phagosome   
NDEx NetworkVAMP3
Atlas of Cancer Signalling NetworkVAMP3
Wikipedia pathwaysVAMP3
Orthology - Evolution
OrthoDB9341
GeneTree (enSembl)ENSG00000049245
Phylogenetic Trees/Animal Genes : TreeFamVAMP3
HOVERGENQ15836
HOGENOMQ15836
Homologs : HomoloGeneVAMP3
Homology/Alignments : Family Browser (UCSC)VAMP3
Gene fusions - Rearrangements
Fusion : MitelmanRERE/VAMP3 [1p36.23/1p36.23]  [t(1;1)(p36;p36)]  
Fusion: TCGARERE 1p36.23 VAMP3 1p36.23 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVAMP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VAMP3
dbVarVAMP3
ClinVarVAMP3
1000_GenomesVAMP3 
Exome Variant ServerVAMP3
ExAC (Exome Aggregation Consortium)VAMP3 (select the gene name)
Genetic variants : HAPMAP9341
Genomic Variants (DGV)VAMP3 [DGVbeta]
DECIPHERVAMP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVAMP3 
Mutations
ICGC Data PortalVAMP3 
TCGA Data PortalVAMP3 
Broad Tumor PortalVAMP3
OASIS PortalVAMP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVAMP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVAMP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VAMP3
DgiDB (Drug Gene Interaction Database)VAMP3
DoCM (Curated mutations)VAMP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VAMP3 (select a term)
intoGenVAMP3
Cancer3DVAMP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603657   
Orphanet
MedgenVAMP3
Genetic Testing Registry VAMP3
NextProtQ15836 [Medical]
TSGene9341
GENETestsVAMP3
Target ValidationVAMP3
Huge Navigator VAMP3 [HugePedia]
snp3D : Map Gene to Disease9341
BioCentury BCIQVAMP3
ClinGenVAMP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9341
Chemical/Pharm GKB GenePA37268
Clinical trialVAMP3
Miscellaneous
canSAR (ICR)VAMP3 (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVAMP3
EVEXVAMP3
GoPubMedVAMP3
iHOPVAMP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:02:21 CEST 2017

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