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VAMP4 (vesicle associated membrane protein 4)

Identity

Other aliasVAMP-4
VAMP24
HGNC (Hugo) VAMP4
LocusID (NCBI) 8674
Atlas_Id 56459
Location 1q24.3  [Link to chromosome band 1q24]
Location_base_pair Starts at 171700156 and ends at 171742239 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;11)(q14;q23) KMT2A/PICALM::inv(11)(q14q23) KMT2A/PICALM


External links

Nomenclature
HGNC (Hugo)VAMP4   12645
Cards
Entrez_Gene (NCBI)VAMP4  8674  vesicle associated membrane protein 4
AliasesVAMP-4; VAMP24
GeneCards (Weizmann)VAMP4
Ensembl hg19 (Hinxton)ENSG00000117533 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117533 [Gene_View]  chr1:171700156-171742239 [Contig_View]  VAMP4 [Vega]
ICGC DataPortalENSG00000117533
TCGA cBioPortalVAMP4
AceView (NCBI)VAMP4
Genatlas (Paris)VAMP4
WikiGenes8674
SOURCE (Princeton)VAMP4
Genetics Home Reference (NIH)VAMP4
Genomic and cartography
GoldenPath hg38 (UCSC)VAMP4  -     chr1:171700156-171742239 -  1q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VAMP4  -     1q24.3   [Description]    (hg19-Feb_2009)
EnsemblVAMP4 - 1q24.3 [CytoView hg19]  VAMP4 - 1q24.3 [CytoView hg38]
Mapping of homologs : NCBIVAMP4 [Mapview hg19]  VAMP4 [Mapview hg38]
OMIM606909   
Gene and transcription
Genbank (Entrez)AF044310 AF052100 AK056124 AK123624 AK290441
RefSeq transcript (Entrez)NM_001185127 NM_003762 NM_201994
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VAMP4
Cluster EST : UnigeneHs.6651 [ NCBI ]
CGAP (NCI)Hs.6651
Alternative Splicing GalleryENSG00000117533
Gene ExpressionVAMP4 [ NCBI-GEO ]   VAMP4 [ EBI - ARRAY_EXPRESS ]   VAMP4 [ SEEK ]   VAMP4 [ MEM ]
Gene Expression Viewer (FireBrowse)VAMP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8674
GTEX Portal (Tissue expression)VAMP4
Human Protein AtlasENSG00000117533-VAMP4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75379   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75379  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75379
Splice isoforms : SwissVarO75379
PhosPhoSitePlusO75379
Domaine pattern : Prosite (Expaxy)SYNAPTOBREVIN (PS00417)    V_SNARE (PS50892)   
Domains : Interpro (EBI)Synaptobrevin   
Domain families : Pfam (Sanger)Synaptobrevin (PF00957)   
Domain families : Pfam (NCBI)pfam00957   
Conserved Domain (NCBI)VAMP4
DMDM Disease mutations8674
Blocks (Seattle)VAMP4
SuperfamilyO75379
Human Protein Atlas [tissue]ENSG00000117533-VAMP4 [tissue]
Peptide AtlasO75379
HPRD06070
IPIIPI00299667   IPI00219648   
Protein Interaction databases
DIP (DOE-UCLA)O75379
IntAct (EBI)O75379
FunCoupENSG00000117533
BioGRIDVAMP4
STRING (EMBL)VAMP4
ZODIACVAMP4
Ontologies - Pathways
QuickGOO75379
Ontology : AmiGOGolgi membrane  SNARE binding  microtubule cytoskeleton organization  SNAP receptor activity  protein binding  lysosome  endosome  Golgi apparatus  plasma membrane  exocytosis  ER to Golgi vesicle-mediated transport  synaptic vesicle  cell surface  transport vesicle  integral component of synaptic vesicle membrane  clathrin-coated vesicle membrane  SNARE complex  trans-Golgi network membrane  SNARE complex assembly  Golgi to plasma membrane protein transport  membrane organization  Golgi ribbon formation  
Ontology : EGO-EBIGolgi membrane  SNARE binding  microtubule cytoskeleton organization  SNAP receptor activity  protein binding  lysosome  endosome  Golgi apparatus  plasma membrane  exocytosis  ER to Golgi vesicle-mediated transport  synaptic vesicle  cell surface  transport vesicle  integral component of synaptic vesicle membrane  clathrin-coated vesicle membrane  SNARE complex  trans-Golgi network membrane  SNARE complex assembly  Golgi to plasma membrane protein transport  membrane organization  Golgi ribbon formation  
Pathways : KEGGSNARE interactions in vesicular transport   
NDEx NetworkVAMP4
Atlas of Cancer Signalling NetworkVAMP4
Wikipedia pathwaysVAMP4
Orthology - Evolution
OrthoDB8674
GeneTree (enSembl)ENSG00000117533
Phylogenetic Trees/Animal Genes : TreeFamVAMP4
HOVERGENO75379
HOGENOMO75379
Homologs : HomoloGeneVAMP4
Homology/Alignments : Family Browser (UCSC)VAMP4
Gene fusions - Rearrangements
Tumor Fusion PortalVAMP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVAMP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VAMP4
dbVarVAMP4
ClinVarVAMP4
1000_GenomesVAMP4 
Exome Variant ServerVAMP4
ExAC (Exome Aggregation Consortium)ENSG00000117533
GNOMAD BrowserENSG00000117533
Genetic variants : HAPMAP8674
Genomic Variants (DGV)VAMP4 [DGVbeta]
DECIPHERVAMP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVAMP4 
Mutations
ICGC Data PortalVAMP4 
TCGA Data PortalVAMP4 
Broad Tumor PortalVAMP4
OASIS PortalVAMP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVAMP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVAMP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VAMP4
DgiDB (Drug Gene Interaction Database)VAMP4
DoCM (Curated mutations)VAMP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VAMP4 (select a term)
intoGenVAMP4
Cancer3DVAMP4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606909   
Orphanet
DisGeNETVAMP4
MedgenVAMP4
Genetic Testing Registry VAMP4
NextProtO75379 [Medical]
TSGene8674
GENETestsVAMP4
Target ValidationVAMP4
Huge Navigator VAMP4 [HugePedia]
snp3D : Map Gene to Disease8674
BioCentury BCIQVAMP4
ClinGenVAMP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8674
Chemical/Pharm GKB GenePA37269
Clinical trialVAMP4
Miscellaneous
canSAR (ICR)VAMP4 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVAMP4
EVEXVAMP4
GoPubMedVAMP4
iHOPVAMP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:41:12 CET 2017

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