Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

VASN (vasorin)

Identity

Alias_namesSLITL2
slit-like 2 (Drosophila)
Other alias
HGNC (Hugo) VASN
LocusID (NCBI) 114990
Atlas_Id 53945
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 4371848 and ends at 4383528 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
VASN (16p13.3) / RBFOX1 (16p13.3)VASN 16p13.3 / RBFOX1 16p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VASN   18517
Cards
Entrez_Gene (NCBI)VASN  114990  vasorin
AliasesSLITL2
GeneCards (Weizmann)VASN
Ensembl hg19 (Hinxton)ENSG00000168140 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168140 [Gene_View]  chr16:4371848-4383528 [Contig_View]  VASN [Vega]
ICGC DataPortalENSG00000168140
TCGA cBioPortalVASN
AceView (NCBI)VASN
Genatlas (Paris)VASN
WikiGenes114990
SOURCE (Princeton)VASN
Genetics Home Reference (NIH)VASN
Genomic and cartography
GoldenPath hg38 (UCSC)VASN  -     chr16:4371848-4383528 +  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VASN  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblVASN - 16p13.3 [CytoView hg19]  VASN - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIVASN [Mapview hg19]  VASN [Mapview hg38]
OMIM608843   
Gene and transcription
Genbank (Entrez)AY166584 AY358298 AY358299 BC013767 BC068575
RefSeq transcript (Entrez)NM_138440
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_052966 NT_187608
Consensus coding sequences : CCDS (NCBI)VASN
Cluster EST : UnigeneHs.372579 [ NCBI ]
CGAP (NCI)Hs.372579
Alternative Splicing GalleryENSG00000168140
Gene ExpressionVASN [ NCBI-GEO ]   VASN [ EBI - ARRAY_EXPRESS ]   VASN [ SEEK ]   VASN [ MEM ]
Gene Expression Viewer (FireBrowse)VASN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114990
GTEX Portal (Tissue expression)VASN
Human Protein AtlasENSG00000168140-VASN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6EMK4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6EMK4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6EMK4
Splice isoforms : SwissVarQ6EMK4
PhosPhoSitePlusQ6EMK4
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    FN3 (PS50853)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    EGF-like_CS    EGF-like_dom    FN3_dom    Ig-like_fold    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)EGF (PF00008)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00008    pfam13855   
Domain families : Smart (EMBL)EGF (SM00181)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)VASN
DMDM Disease mutations114990
Blocks (Seattle)VASN
SuperfamilyQ6EMK4
Human Protein Atlas [tissue]ENSG00000168140-VASN [tissue]
Peptide AtlasQ6EMK4
HPRD10587
IPIIPI00395488   
Protein Interaction databases
DIP (DOE-UCLA)Q6EMK4
IntAct (EBI)Q6EMK4
FunCoupENSG00000168140
BioGRIDVASN
STRING (EMBL)VASN
ZODIACVASN
Ontologies - Pathways
QuickGOQ6EMK4
Ontology : AmiGOprotein binding  extracellular space  mitochondrion  lysosomal membrane  plasma membrane  cell surface  negative regulation of epithelial to mesenchymal transition  integral component of membrane  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  cadherin binding  transforming growth factor beta binding  extracellular exosome  cellular response to hypoxia  cellular response to redox state  
Ontology : EGO-EBIprotein binding  extracellular space  mitochondrion  lysosomal membrane  plasma membrane  cell surface  negative regulation of epithelial to mesenchymal transition  integral component of membrane  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  cadherin binding  transforming growth factor beta binding  extracellular exosome  cellular response to hypoxia  cellular response to redox state  
NDEx NetworkVASN
Atlas of Cancer Signalling NetworkVASN
Wikipedia pathwaysVASN
Orthology - Evolution
OrthoDB114990
GeneTree (enSembl)ENSG00000168140
Phylogenetic Trees/Animal Genes : TreeFamVASN
HOVERGENQ6EMK4
HOGENOMQ6EMK4
Homologs : HomoloGeneVASN
Homology/Alignments : Family Browser (UCSC)VASN
Gene fusions - Rearrangements
Fusion : MitelmanVASN/RBFOX1 [16p13.3/16p13.3]  
Fusion: TCGA_MDACCVASN 16p13.3 RBFOX1 16p13.3 GBM
Tumor Fusion PortalVASN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVASN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VASN
dbVarVASN
ClinVarVASN
1000_GenomesVASN 
Exome Variant ServerVASN
ExAC (Exome Aggregation Consortium)ENSG00000168140
GNOMAD BrowserENSG00000168140
Genetic variants : HAPMAP114990
Genomic Variants (DGV)VASN [DGVbeta]
DECIPHERVASN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVASN 
Mutations
ICGC Data PortalVASN 
TCGA Data PortalVASN 
Broad Tumor PortalVASN
OASIS PortalVASN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVASN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVASN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VASN
DgiDB (Drug Gene Interaction Database)VASN
DoCM (Curated mutations)VASN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VASN (select a term)
intoGenVASN
Cancer3DVASN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608843   
Orphanet
DisGeNETVASN
MedgenVASN
Genetic Testing Registry VASN
NextProtQ6EMK4 [Medical]
TSGene114990
GENETestsVASN
Target ValidationVASN
Huge Navigator VASN [HugePedia]
snp3D : Map Gene to Disease114990
BioCentury BCIQVASN
ClinGenVASN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114990
Chemical/Pharm GKB GenePA134974883
Clinical trialVASN
Miscellaneous
canSAR (ICR)VASN (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVASN
EVEXVASN
GoPubMedVASN
iHOPVASN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:41:14 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.