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VASP (vasodilator-stimulated phosphoprotein)

Identity

Other alias-
HGNC (Hugo) VASP
LocusID (NCBI) 7408
Atlas_Id 46391
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 46010688 and ends at 46030240 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LOC100507412 (-) / VASP (19q13.32)VASP (19q13.32) / CYP2S1 (19q13.2)VASP 19q13.32 / CYP2S1 19q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VASP   12652
Cards
Entrez_Gene (NCBI)VASP  7408  vasodilator-stimulated phosphoprotein
Aliases
GeneCards (Weizmann)VASP
Ensembl hg19 (Hinxton)ENSG00000125753 [Gene_View]  chr19:46010688-46030240 [Contig_View]  VASP [Vega]
Ensembl hg38 (Hinxton)ENSG00000125753 [Gene_View]  chr19:46010688-46030240 [Contig_View]  VASP [Vega]
ICGC DataPortalENSG00000125753
TCGA cBioPortalVASP
AceView (NCBI)VASP
Genatlas (Paris)VASP
WikiGenes7408
SOURCE (Princeton)VASP
Genetics Home Reference (NIH)VASP
Genomic and cartography
GoldenPath hg19 (UCSC)VASP  -     chr19:46010688-46030240 +  19q13.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)VASP  -     19q13.32   [Description]    (hg38-Dec_2013)
EnsemblVASP - 19q13.32 [CytoView hg19]  VASP - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIVASP [Mapview hg19]  VASP [Mapview hg38]
OMIM601703   
Gene and transcription
Genbank (Entrez)AK314812 AL556269 BC026019 BC038224 BG751094
RefSeq transcript (Entrez)NM_001008736 NM_003370
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)VASP
Cluster EST : UnigeneHs.515469 [ NCBI ]
CGAP (NCI)Hs.515469
Alternative Splicing GalleryENSG00000125753
Gene ExpressionVASP [ NCBI-GEO ]   VASP [ EBI - ARRAY_EXPRESS ]   VASP [ SEEK ]   VASP [ MEM ]
Gene Expression Viewer (FireBrowse)VASP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7408
GTEX Portal (Tissue expression)VASP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50552   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50552  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50552
Splice isoforms : SwissVarP50552
PhosPhoSitePlusP50552
Domaine pattern : Prosite (Expaxy)WH1 (PS50229)   
Domains : Interpro (EBI)PH_dom-like    Vasodilator_phosphoprotein    VASP_tetra    WH1/EVH1_dom   
Domain families : Pfam (Sanger)VASP_tetra (PF08776)    WH1 (PF00568)   
Domain families : Pfam (NCBI)pfam08776    pfam00568   
Domain families : Smart (EMBL)WH1 (SM00461)  
Conserved Domain (NCBI)VASP
DMDM Disease mutations7408
Blocks (Seattle)VASP
PDB (SRS)1EGX    1JNG    1USD    1USE    2PAV    2PBD    3CHW   
PDB (PDBSum)1EGX    1JNG    1USD    1USE    2PAV    2PBD    3CHW   
PDB (IMB)1EGX    1JNG    1USD    1USE    2PAV    2PBD    3CHW   
PDB (RSDB)1EGX    1JNG    1USD    1USE    2PAV    2PBD    3CHW   
Structural Biology KnowledgeBase1EGX    1JNG    1USD    1USE    2PAV    2PBD    3CHW   
SCOP (Structural Classification of Proteins)1EGX    1JNG    1USD    1USE    2PAV    2PBD    3CHW   
CATH (Classification of proteins structures)1EGX    1JNG    1USD    1USE    2PAV    2PBD    3CHW   
SuperfamilyP50552
Human Protein AtlasENSG00000125753
Peptide AtlasP50552
HPRD03415
IPIIPI00301058   
Protein Interaction databases
DIP (DOE-UCLA)P50552
IntAct (EBI)P50552
FunCoupENSG00000125753
BioGRIDVASP
STRING (EMBL)VASP
ZODIACVASP
Ontologies - Pathways
QuickGOP50552
Ontology : AmiGOneural tube closure  actin binding  protein binding  profilin binding  cytoplasm  cytosol  plasma membrane  bicellular tight junction  focal adhesion  axon guidance  actin polymerization or depolymerization  actin cytoskeleton  SH3 domain binding  positive regulation of actin filament polymerization  lamellipodium membrane  filopodium membrane  cell junction assembly  protein homotetramerization  extracellular exosome  
Ontology : EGO-EBIneural tube closure  actin binding  protein binding  profilin binding  cytoplasm  cytosol  plasma membrane  bicellular tight junction  focal adhesion  axon guidance  actin polymerization or depolymerization  actin cytoskeleton  SH3 domain binding  positive regulation of actin filament polymerization  lamellipodium membrane  filopodium membrane  cell junction assembly  protein homotetramerization  extracellular exosome  
Pathways : KEGGRap1 signaling pathway    Focal adhesion    Fc gamma R-mediated phagocytosis    Leukocyte transendothelial migration   
NDEx NetworkVASP
Atlas of Cancer Signalling NetworkVASP
Wikipedia pathwaysVASP
Orthology - Evolution
OrthoDB7408
GeneTree (enSembl)ENSG00000125753
Phylogenetic Trees/Animal Genes : TreeFamVASP
HOVERGENP50552
HOGENOMP50552
Homologs : HomoloGeneVASP
Homology/Alignments : Family Browser (UCSC)VASP
Gene fusions - Rearrangements
Fusion : MitelmanVASP/CYP2S1 [19q13.32/19q13.2]  
Fusion: TCGAVASP 19q13.32 CYP2S1 19q13.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVASP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VASP
dbVarVASP
ClinVarVASP
1000_GenomesVASP 
Exome Variant ServerVASP
ExAC (Exome Aggregation Consortium)VASP (select the gene name)
Genetic variants : HAPMAP7408
Genomic Variants (DGV)VASP [DGVbeta]
DECIPHER (Syndromes)19:46010688-46030240  ENSG00000125753
CONAN: Copy Number AnalysisVASP 
Mutations
ICGC Data PortalVASP 
TCGA Data PortalVASP 
Broad Tumor PortalVASP
OASIS PortalVASP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVASP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVASP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VASP
DgiDB (Drug Gene Interaction Database)VASP
DoCM (Curated mutations)VASP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VASP (select a term)
intoGenVASP
Cancer3DVASP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601703   
Orphanet
MedgenVASP
Genetic Testing Registry VASP
NextProtP50552 [Medical]
TSGene7408
GENETestsVASP
Huge Navigator VASP [HugePedia]
snp3D : Map Gene to Disease7408
BioCentury BCIQVASP
ClinGenVASP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7408
Chemical/Pharm GKB GenePA37276
Clinical trialVASP
Miscellaneous
canSAR (ICR)VASP (select the gene name)
Probes
Litterature
PubMed156 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVASP
EVEXVASP
GoPubMedVASP
iHOPVASP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:24:41 CEST 2017

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